1428 bp reverse orf at  [07:03]

-> Mtbook page 801

rocE

arginine/ornithine transporter

Function

Classification III. A.1
Category III. Cell processes
Class A. Transport/binding proteins
Group 1. Amino acids

Protein

476 aminoacids, 49,9 kDa

>Rv2320c LPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAGPGVIVSFIIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHPGWVNLPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSADHLKDFVPFGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQETAGLAIILDNVTHGEWASTILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFASTLAAFIPLDSLADMVSIGTLTAFSVVAVGVIVLRVREPDLPRGFKVPGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: rocE, rocE and M. tuberculosis,
arginine/ornithine transporter,
Sanger Rv2320c, Tigr MT2383

543 bp reverse orf at  [07:03]

-> Mtbook page 801

rocD2

ornithine aminotransferase

Function

Classification I. A.2
Category I. Small-molecule metabolism
Class A. Degradation
Group 2. Amino acids and amines

Protein

181 aminoacids, 18,9 kDa

>Rv2321c MIADEIQSGLACTGYPFACDHGGVLPDIYLLGKTLGGGAVPLSAMVADREIFGVVHPGEHGSTFGGNPLAAAIGTPVVSMVVWGECQARSAKLGAHLHQRLADLIGDGAVALRGLGWWADVDIERALAIGTDMSMRLADRGVLLKDTYGAALRFAPPLVITAQEIDCAVRRFADALWEAGS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: rocD2, rocD2 and M. tuberculosis,
ornithine aminotransferase,
Sanger Rv2321c, Tigr MT2384

663 bp reverse orf at  [07:03]

-> Mtbook page 801

rocD1

ornithine aminotransferase

Function

Classification I. A.2
Category I. Small-molecule metabolism
Class A. Degradation
Group 2. Amino acids and amines

Protein

221 aminoacids, 22,7 kDa

>Rv2322c MTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQVDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPAAGSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: rocD1, rocD1 and M. tuberculosis,
ornithine aminotransferase,
Sanger Rv2322c

906 bp reverse orf at  [07:03]

-> Mtbook page 802

Function

unknown

Protein

302 aminoacids, 33 kDa

>Rv2323c MENTQRPSFDCEIRAKYRWFMTDSYVAAARLGSPARRTPRTRRYAMTPPAFFAVAYAINPWMDVTAPVDVQVAQAQWEHLHQTYLRLGHSVDLIEPISGLPDMVYTANGGFIAHDIAVVARFRFPERAGESRAYASWMSSVGYRPVTTRHVNEGQGDLLMVGERVLAGYGFRTDQRAHAEIAAVLGLPVVSLELVDPRFYHLDTALAVLDDHTIAYYPPAFSTAAQEQLSALFPDAIVVGSADAFVFGLNAVSDGLNVVLPVAAMGFAAQLRAAGFEPVGVDLSELLKGGGSVKCCTLEIHP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv2323c, Tigr MT2385

444 bp forward orf at  [07:03]

-> Mtbook page 802

transcriptional regulator (Lrp/AsnC family)

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

148 aminoacids, 16,4 kDa

>Rv2324 MDRLDDTDERILAELAEHARATFAEIGHKVSLSAPAVKRRVDRMLESGVIKGFTTVVDRNALGWNTEAYVQIFCHGRIAPDQLRAAWVNIPEVVSAATVTGTSDAILHVLAHDMRHLEAALERIRSSADVERSESTVVLSNLIDRMPP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

transcriptional regulator (Lrp/AsnC family),
Sanger Rv2324, Tigr MT2386

846 bp reverse orf at  [07:03]

-> Mtbook page 802

Function

unknown

Protein

282 aminoacids, 30 kDa

>Rv2325c MTTTSAPARNGTRRPSRPIVLLIPVPGSSVIHDLWAGTKLLVVFGISVLLTFYPGWVTIGMMAALVLAAARIAHIPRGALPSVPRWLWIVLAIGFLTAALAGGTPVVAVGGVQLGLGGALHFLRITALSVVLLALGAMVSWTTNVAEISPAVATLGRPFRVLRIPVDEWAVALALALRAFPMLIDEFQVLYAARRLRPKRMPPSRKARRQRHARELIDLLAAAITVTLRRADEMGDAITARGGTGQLSAHPGRPKLADWVTLAITAMASGTAVAIESLILHS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv2325c, Tigr MT2387

2091 bp reverse orf at  [07:03]

-> Mtbook page 802

ABC transporter

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

697 aminoacids, 72,8 kDa

>Rv2326c MCCAVCGPEPGRIGEVTPLGPCPAQHRGGPLRPSELAQASVMAALCAVTAIISVVVPFAAGLALLGTVPTGLLAYRYRLRVLAAATVAAGMIAFLIAGLGGFMGVVHSAYIGGLTGIVKRRGRGTPTVVVSSLIGGFVFGAAMVGMLAAMVRLRHLIFKVMTANVDGIAATLARMHMQGAAADVKRYFAEGLQYWPWVLLGYFNIGIMIVSLIGWWALSRLLERMRGIPDVHKLDPPPGDDVDALIGPVPVRLDKVRFRYPRAGQDALREVSLDVRAGEHLAIIGANGSGKTTLMLILAGRAPTSGTVDRPGTVGLGKLGGTAVVLQHPESQVLGTRVADDVVWGLPLGTTADVGRLLSEVGLEALAERDTGSLSGGELQRLALAAALAREPAMLIADEVTTMVDQQGRDALLAVLSGLTQRHRTALVHITHYDNEADSADRTLSLSDSPDNTDMVHTAAMPAPVIGVDQPQHAPALELVGVGHEYASGTPWAKTALRDINFVVEQGDGVLIHGGNGSGKSTLAWIMAGLTIPTTGACLLDGRPTHEQVGAVALSFQAARLQLMRSRVDLEVASAAGFSASEQDRVAAALTVVGLDPALGARRIDQLSGGQMRRVVLAGLLARAPRALILDEPLAGLDAASQRGLLRLLEDLRRARGLTVVVVSHDFAGMEELCPRTLHLRDGVLESAAASEAGGMS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

ABC transporter,
Sanger Rv2326c, Tigr MT2388

489 bp forward orf at  [07:04]

-> Mtbook page 803

Function

unknown

Protein

163 aminoacids, 17,2 kDa

>Rv2327 MSPSPAAANRSEVGGPLPGLGADLLAVVARLNRLATQRIQMPLPAAQARLLATIEAQGEARIGDLAAVDHCSQPTMTTQVRRLEDAGLVTRTADPGDARAVRIRITPEGIRTLTAVRADRAAAIEPQLALLPPADRRVLADAVDVLRRLLDHAATTPGRATRQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv2327, Tigr MT2389

1146 bp forward orf at  [07:04]

-> Mtbook page 803

PE

Function

Classification IV. C.1.a
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup a

Protein

382 aminoacids, 36,8 kDa

>Rv2328 MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLLKTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSAGAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAATGLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE, PE and M. tuberculosis,
Sanger Rv2328, Tigr MT2390

1545 bp reverse orf at  [07:04]

-> Mtbook page 804

narK1

probable nitrite extrusion protein

Function

Classification III. A.4
Category III. Cell processes
Class A. Transport/binding proteins
Group 4. Anions

Protein

515 aminoacids, 55,1 kDa

>Rv2329c MEQHTLLQREESPRSPAAPSLRRLGGSRHITHWDPEDLGAWEAGNKGIARRNLLWSVVTVHLGYSVWTLWPVLELLMPQDVYGFSTSDKFLLGTIATLFGAFLRMPYALASAIFGGRNWATFSAIVLLIPAIGTTVLLTHPGLPLWPYLVCAALTGLGGGNFASSMSNANAFYPHRLKGSALGIAGGVGNLGVPAIQLVGLLAIATVGERKPYLVCALYVVLVAIAVIGVSLFMNNVEQHRVQVNRLRPIVSAVLSTRDTWLLSLLYLGTFGSFIGFSFVFGQVLQTNFLACGQSPARATLHAVELAFVGPLLAAVARIYGGRLADRVGGSRLTLIVFVAMTLAAGLLISASTLEGRHVGQHRGATMVGYFVCFVALFVLSGLGNGSVYKMIPTIFEACSRSLDLSEAERRDWSRIISGVVIGFVAAFGALGGVGINMALRESYLSTGSGTDAFWIFMMCYAAAAVLTWKVYDRRTVTDMGMLQAALVRQPASTPAELIGPRTQSDRFSGCSISA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: narK1, narK1 and M. tuberculosis,
probable nitrite extrusion protein,
Sanger Rv2329c, Tigr MT2391

525 bp reverse orf at  [07:04]

-> Mtbook page 804

lppP

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

175 aminoacids, 18,8 kDa

>Rv2330c VRRQRSAVPILALLALLALLALIVGLGASGCAWKPPTTRPSPPNTCKDSDGPTADTVRQAIAAVPIVVPGSKWVEITRGHTRNCRLHWVQIIPTIASQSTPQQLLFFDRNIPLGSPTRNPKPYITVLPAGDDTVTVQYQWQIGSDQECCPTGIGTVRFHIGSDGKLEALGSIPHQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lppP, lppP and M. tuberculosis,
lipoprotein,
Sanger Rv2330c, Tigr MT2392

384 bp forward orf at  [07:05]

-> Mtbook page 804

Function

unknown

Protein

128 aminoacids, 13,7 kDa

>Rv2331 VPPVFLPQIGRLTPDAVGEAIGIAADDIPMAARWIGSRPCSLIGQPNTMGDEMGYLGPGLAGQRCVDRLVMGASRSTCSRLPVIASVDERLSVLKPVRPRLHSISFIFKGRPGEVYLTVTGYNFRGVP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv2331, Tigr MT2393

1956 bp forward orf at  [07:05]

-> Mtbook page 804

mez

probable malate oxidoreductase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

652 aminoacids, 70,7 kDa

>Rv2332 MVESGTGIPLPASCWSRTRSRRCMPKDSSPHWIWHSSAARAALYVRGKRRPDGQGRRSCALRNRGRTPATGPGPGQSPSPVGARQPALPSRRPLNPARSRTEVVMSDARVPRIPAALSAPSLNRGVGFTHAQRRRLGLTGRLPSAVLTLDQQAERVWHQLQSLATELGRNLLLEQLHYRHEVLYFKVLADHLPELMPVVYTPTVGEAIQRFSDEYRGQRGLFLSIDEPDEIEEAFNTLGLGPEDVDLIVCTDAEAILGIGDWGVGGIQIAVGKLALYTAGGGVDPRRCLAVSLDVGTDNEQLLADPFYLGNRHARRRGREYDEFVSRYIETAQRLFPRAILHFEDFGPANARKILDTYGTDYCVFNDDMQGTGAVVLAAVYSGLKVTGIPLRDQTIVVFGAGTAGMGIADQIRDAMVADGATLEQAVSQIWPIDRPGLLFDDMDDLRDFQVPYAKNRHQLGVAVGDRVGLSDAIKIASPTILLGCSTVYGAFTKEVVEAMTASCKHPMIFPLSNPTSRMEAIPADVLAWSNGRALLATGSPVAPVEFDETTYVIGQANNVLAFPGIGLGVIVAGARLITRRMLHAAAKAIAHQANPTNPGDSLLPDVQNLRAISTTVAEAVYRAAVQDGVASRTHDDVRQAIVDTMWLPAYD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: mez, mez and M. tuberculosis,
probable malate oxidoreductase,
Sanger Rv2332, Tigr MT2394

1611 bp reverse orf at  [07:05]

-> Mtbook page 805

probable tetracenomycin C resistance protein

Function

Classification III. A.6
Category III. Cell processes
Class A. Transport/binding proteins
Group 6. Efflux proteins

Protein

537 aminoacids, 57,1 kDa

>Rv2333c MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVALLVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable tetracenomycin C resistance protein,
Sanger Rv2333c, Tigr MT2395

930 bp forward orf at  [07:05]

-> Mtbook page 806

cysK

cysteine synthase A

Function

Classification I. D.3
Category I. Small-molecule metabolism
Class D. Amino acid biosynthesis
Group 3. Serine family

Protein

310 aminoacids, 32,8 kDa

>Rv2334 MSIAEDITQLIGRTPLVRLRRVTDGAVADIVAKLEFFNPANSVKDRIGVAMLQAAEQAGLIKPDTIILEPTSGNTGIALAMVCAARGYRCVLTMPETMSLERRMLLRAYGAELILTPGADGMSGAIAKAEELAKTDQRYFVPQQFENPANPAIHRVTTAEEVWRDTDGKVDIVVAGVGTGGTITGVAQVIKERKPSARFVAVEPAASPVLSGGQKGPHPIQGIGAGFVPPVLDQDLVDEIITVGNEDALNVARRLAREEGLLVGISSGAATVAALQVARRPENAGKLIVVVLPDFGERYLSTPLFADVAD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: cysK, cysK and M. tuberculosis,
cysteine synthase A,
Sanger Rv2334, Tigr MT2397

687 bp forward orf at  [07:05]

-> Mtbook page 806

cysE

serine acetyltransferase

Function

Classification I. D.3
Category I. Small-molecule metabolism
Class D. Amino acid biosynthesis
Group 3. Serine family

Protein

229 aminoacids, 23,8 kDa

>Rv2335 MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHPGAVIGARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVVVGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: cysE, cysE and M. tuberculosis,
serine acetyltransferase,
Sanger Rv2335

966 bp forward orf at  [07:06]

-> Mtbook page 806

Function

unknown

Protein

322 aminoacids, 35,3 kDa

>Rv2336 MDVPHEQPALSSSKSNRFTSQRQTTGVGTTTVERLEPRLSPASRHITEAKAFGTECHVSSFTREQDPDRAVRVEQIHGEAYVAAGHVYESALDELGRLDNSNAEFILDKARGSTRETEVIYLHAVPAEPLSGSQGEGGLRIVGISAVGSIDDLSAFKAAKPSMGLAHQRKLYDAIEDLGHGGVKEIAALSVTADAPPTVSYSLIREVLRLYHRTGEKLIITFAMPAYAKMVMNFGRFAMPQVGEPFYAHRNNDPRTSNDLLLVPSIVEPSNFLENISRGVVTADDGPTARRRFATLCYMTDGLDDYFMPLTRQVLSEGIQDI*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv2336, Tigr MT2399

1116 bp reverse orf at  [07:06]

-> Mtbook page 807

Function

unknown

Protein

372 aminoacids, 41,3 kDa

>Rv2337c MRAGRWGPGMTGLDPAEFLSLVEAAALAPSADNRREVQLEHAGRRVRLWGDQTWRSAPEHRRIMSLVAIGAAVENVKLRAGRLGFETKVCWFPDSGNPGLVAEIDVDRLPQTRVDPIEGAIERRRTNRRVRFRGPPLSQGELGALSAEATGIDGIQLHWFDSPETRKQILRLVRLAETERFRSRELHEELFSAVRFDIGWTASSDDGLPPGSLEVEAWMRPMFRGLRHWRVLRLLRTVGMHHALGLRAAYLPCRLAPHVGALTTSLDLASGALTAGAVFERIWLRTTLLGAELQPFAASAVLSLPACEWVAPHVRAALVGGWNLLAPGHWPMMVFRIGHARAPSVRTMRQSVEAYCYAPAERSGSDSESRFA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv2337c, Tigr MT2400

954 bp reverse orf at  [07:06]

-> Mtbook page 807

moeW

molybdopterin biosynthesis

Function

Classification I. G.4
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 4. Molybdopterin

Protein

318 aminoacids, 35,3 kDa

>Rv2338c MRAGADAPDSGRVKESAPWSYDEAFCRNLGLISPTEQQRLRNSRVAIAGMGGVGGIDMVALARMGIGKFTIADPDVFEIRNSNRQYGAMRSTNGQAKAEVMRNIVHDINPEAEIRAFCEPIGKENAATFLEGADVLVDGIDAFEIDLRRLLYREAQQRGIYALGAGPLGFSTAWVVFDPKGMTFDRYFDLSDAMNTVDKFVAFIAGIAPSATHRRSIDLSYVDIENRTGPSVGLACHLASGVVAAEVLKILLGHGRVYAAPYFHQFDAYRSIYVRKRLRCGNRHPLQRVKRRLLARYINRRSAGVIPGLRYHRTEPSY*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: moeW, moeW and M. tuberculosis,
molybdopterin biosynthesis,
Sanger Rv2338c, Tigr MT2401

2886 bp forward orf at  [07:06]

-> Mtbook page 808

mmpL9

conserved large membrane protein

Function

Classification II. C.4
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 4. Conserved membrane proteins

Protein

962 aminoacids, 104,6 kDa

>Rv2339 MVPGEVHMSDTPSGPHPIIPRTIRLAAIPILLCWLGFTVFVSVAVPPLEAIGETRAVAVAPDDAQSMRAMRRAGKVFNEFDSNSIAMVVLESDQPLGEKAHRYYDHLVDTLVLDQSHIQHIQDFWRDPLTAAGAVSADGKAAYVQLYLAGNMGEALANESVEAVRKIVANSTPPEGIRTYVTGPAALFADQIAAGDRSMKLITGLTFAVITVLLLLVYRSIATTLLILPMVFIGLGATRGTIAFLGYHGMVGLSTFVVNILTALAIAAGTDYAIFLVGRYQEARHIGQNREASFYTMYRGTANVILGSGLTIAGATYCLSFARLTLFHTMGPPLAIGMLVSVAAALTLAPAIIAIAGRFGLLDPKRRLKTRGWRRVGTAVVRWPGPILATSVALALVGLLALPGYRPGYNDRYYLRAGTPVNRGYAAADRHFGPARMNPEMLLVESDQDMRNPAGMLVIDKIAKEVLHVSGVERVQAITRPQGVPLEHASIPFQISMMGATQTMSLPYMRERMADMLTMSDEMLVAINSMEQMLDLVQQLNDVTHEMAATTREIKATTSELRDHLADIDDFVRPLRSYFYWEHHCFDIPLCSATRSLFDTLDGVDTLTDQLRALTDDMNKMEALTPQFLALLPPMITTMKTMRTMMLTMRSTISGVQDQMADMQDHATAMGQAFDTAKSGDSFYLPPEAFDNAEFQQGMKLFLSPNGKAVRFVISHESDPASTEGIDRIEAIRAATKDAIKATPLQGAKIYIGGTAATYQDIRDGTKYDILIVGIAAVCLVFIVMLMITQSLIASLVIVGTVLLSLGTAFGLSVLIWQHFVGLQVHWTIVAMSVIVLLAVGSDYNLLLVSRFKEEVGAGLKTGIIRAMAGTGAVVTSAGLVFAFTMASMAVSELRVIGQVGTTIGLGLLFDTLVVRSFMTPSIAALLGRWFWWPNMIHSRPTVPEAHTRQGARRIQPHLHRG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: mmpL9, mmpL9 and M. tuberculosis,
conserved large membrane protein,
Sanger Rv2339, Tigr MT2402

1239 bp reverse orf at  [07:07]

-> Mtbook page 808

PE

Function

Classification IV. C.1.a
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup a

Protein

413 aminoacids, 38,7 kDa

>Rv2340c MSHVTAAPNVLAASAGELAAIGSTMRAANAAAAAPTAGVLAAGGDDVSAGIAALFGARAQAYQAISAQAALFHDRFVQILQEGAAAYAMAEAANALPLQKAQGVVSELAQDRTGGTGTGQSRGAGGFGGVGQAGGKGWDGGPIGNGQVGEQHGAGQLGSTDGNPGVAGAAHGSGVSASHGSGATGAAGVADPGGSGAGVGSAAGNGTGAGSADAVGGAGTGRDIVGSVRGDGGVGMASGDGGLSTGAAGASAEGGLMPGFGGAPWVGGHWGLGGEGHSGAIGGVGEQVAPAVATAPAVSPATTSAVAAESGSTPATKAQAMHATTNPGNAAHQGNPADPGNSARRADGGRDEQLLLLPLTSLRGLRHTLKKLSGLRARNGLLTASGDNASGSGRPWDRDQLLRALGLRPPGHE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE, PE and M. tuberculosis,
Sanger Rv2340c

417 bp forward orf at  [07:07]

-> Mtbook page 809

lppQ

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

139 aminoacids, 14,1 kDa

>Rv2341 MPVGGRQHVFEKLASILGLVAAPLMLLGLSACGRSAGKTSEPTCPTEPIDAADSSTTPDPSCVVRATEINGNGSRIQTWTGSYDAAATQSGGVCGGTCNFHATVRFTVDEGQISGSVDQVYQAAMVAIATRPTSPSLAP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lppQ, lppQ and M. tuberculosis,
lipoprotein,
Sanger Rv2341, Tigr MT2406

255 bp forward orf at  [07:07]

-> Mtbook page 809

Function

unknown

Protein

85 aminoacids, 9,2 kDa

>Rv2342 LIGYVAVLGLGYVLGAKAGRRRYEQIASTYRALTGSPVARSMIEGGRRKIANRISPDAGFVTLAEIDNQTAVVQRGVERQPKTAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv2342, Tigr MT2407

1917 bp reverse orf at  [07:07]

-> Mtbook page 809

dnaG

DNA primase

Function

Classification II. A.5
Category II. Macromolecule metabolism
Class A. Synthesis and modification of macromolecules
Group 5. DNA replication, repair, recombination and restriction/ modification

Protein

639 aminoacids, 69,6 kDa

>Rv2343c MSGRISDRDIAAIREGARIEDVVGDYVQLRRAGADSLKGLCPFHNEKSPSFHVRPNHGHFHCFGCGEGGDVYAFIQKIEHVSFVEAVELLADRIGHTISYTGAATSVQRDRGSRSRLLAANAAAAAFYAQALQSDEAAPARQYLTERSFDAAAARKFGCGFAPSGWDSLTKHLQRKGFEFEELEAAGLSRQGRHGPMDRFHRRLLWPIRTSAGEVVGFGARRLFDDDAMEAKYVNTPETLLYKKSSVMFGIDLAKRDIAKGHQAVVVEGYTDVMAMHLAGVTTAVASCGTAFGGEHLAMLRRLMMDDSFFRGELIYVFDGDEAGRAAALKAFDGEQKLAGQSFVAVAPDGMDPCDLRLKCGDAALRDLVARRTPLFEFAIRAAIAEMDLDSAEGRVAALRRCVPMVGQIKDPTLRDEYARQLAGWVGWADVAQVIGRVRGEAKRTKHPRLGRLGSTTIARAAQRPTAGPPTELAVRPDPRDPTLWPQREALKSALQYPALAGPVFDALTVEGFTHPEYAAVRAAIDTAGGTSAGLSGAQWLDMVRQQTTSTVTSALISELGVEAIQVDDDKLPRYIAGVLARLQEVWLGRQIAEVKSKLQRMSPIEQGDEYHALFGDLVAMEAYRRSLLEQASGDDLTA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: dnaG, dnaG and M. tuberculosis,
DNA primase,
Sanger Rv2343c, Tigr MT2408

1293 bp reverse orf at  [07:08]

-> Mtbook page 810

dgt

probable deoxyguanosine triphosphate hydrolase

Function

Classification I. F.5
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 5. Miscellaneous nucleoside/nucleotide reactions

Protein

431 aminoacids, 46,9 kDa

>Rv2344c VSASEHDPYDDFDRQRRVAEAPKTAGLPGTEGQYRSDFARDRARVLHSAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDLDLVELAGLAHDIGHPPYGHNGERALDEVAASHGGFEGNAQNFRILTSLEPKVVDAQGLSAGLNLTRASLDAVTKYPWMRGDGLGSQRRKFGFYDDDRESAVWVRQGAPPERACLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLAAEEDAAALARLGEREFSRVSADELMAAARRLSRLPVVAAVGKYDATLSASVALKRLTSELVGRFASAAIATTRAAAGPGPLVRFRADLQVPDLVRAEVAVLKILALQFIMSDPRHLETQARQRERIHRVAHRLYSGAPQTLDPVYAAAFNTAADDAARLRVVVDQIASYTEGRLERIDADQLGVSRNALD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: dgt, dgt and M. tuberculosis,
probable deoxyguanosine triphosphate hydrolase,
Sanger Rv2344c, Tigr MT2409

1980 bp forward orf at  [07:08]

-> Mtbook page 810

precursor of probable membrane protein

Function

Classification II. C.2
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 2. Surface polysaccharides, lipopolysaccharides, proteins and antigens

Protein

660 aminoacids, 70 kDa

>Rv2345 MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTSSGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSALNWAQRTTRTSELGNYDALLAVATTGREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSSRVVLLVTVGIIVIVVAVLLVVMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNELALAIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLRDLVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDAVRAAESALGQARALLDAVDSAATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRARGAADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRAYTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIPTSFGGSSNAPGSSPDGGFLGGGGRF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

precursor of probable membrane protein,
Sanger Rv2345, Tigr MT2410