294 bp reverse orf at  [05:59]

-> Mtbook page 681

Function

unknown

Protein

98 aminoacids, 11,3 kDa

>Rv1959c VSSRYLLSPAAQAHLEEIWDCTYDRWGVDQAEQYLRELQHAIDRAAANPRIGRACDEIRPGYRKLSAGSHTLFYRVTGEGTIDVVRVLHQRMDVDRNL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1959c, Tigr MT2008

249 bp reverse orf at  [05:59]

-> Mtbook page 681

Function

unknown

Protein

83 aminoacids, 9,2 kDa

>Rv1960c VGKNTSFVLDEHYSAFIDGEIAAGRYRSASEVIRSALRLLEDRETQLRALREALEAGERSGSSTPFDFDGFLGRKRADASRGR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1960c, Tigr MT2009

492 bp forward orf at  [05:59]

-> Mtbook page 681

Function

unknown

Protein

164 aminoacids, 17,8 kDa

>Rv1961 VFLPTNAQYQLLVVGVSPWDTPSPSGRISWGSAWPHQARRAQTCQRVRRHWMIDTTEAAYRLTYQPDGTSITVRENLVDILARELLGPIRGPQEVLPFSPRSQYLVGHLAPVKLTGAALIDDNAVQARANAEALAEGGGVPAYAADETTPTPTTTPKTAHPSRA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1961, Tigr MT2010

405 bp reverse orf at  [05:59]

-> Mtbook page 681

Function

unknown

Protein

135 aminoacids, 14,5 kDa

>Rv1962c VIYLETSALVKLIRIEVESDALADWLDDRTELRWITSALTEVELSRAIRAVSPEGLPAVPSVLARLDRFEIDAVIRSTAAAYPNPALRSLDAIHLATAQTAGSVAPLTALVTYDNRLKEAAEALSLAVVAPGQAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1962c, Tigr MT2012

1218 bp reverse orf at  [05:59]

-> Mtbook page 681

putative transcriptional regulator

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

406 aminoacids, 44,3 kDa

>Rv1963c MASVAQPVRRRPKDRKKQILDQAVGLFIERGFHSVKLEDIAEAAGVTARALYRHYDNKQALLAEAIRTGQDQYQSARRLTEGETEPTPRPLNADLEDLIAAAVASRALTVLWQREARYLNEDDRTAVRRRINAIVAGMRDSVLLEVPDLSPQHSELRAWAVSSTLTSLGRHSLSLPGEELKKLLYQACMAAARTPPVCELPPLPAGDAARDEADVLFSRYETLLAAGARLFRAQGYPAVNTSEIGKGAGIAGPGLYRSFSSKQAILDALIRRLDEWRCLECIRALRANQQAAQRLRGLVQGHVRISLDAPDLVAVSVTELSHASVEVRDGYLRNQGDREAVWIDLIGKLVPATSVAQGRLLVAAAISFIEDVARTWHLTRYAGVADEISGLALAILTSGAGNLLRA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative transcriptional regulator,
Sanger Rv1963c, Tigr MT2014

795 bp forward orf at  [06:00]

-> Mtbook page 682

part of mce3operon

Function

Classification IV. A
Category IV. Other
Class A. Virulence

Protein

265 aminoacids, 27,5 kDa

>Rv1964 MVIVADKAAGRVADPVLRPVGALGDFFAMTLDTSVCMFKPPFAWREYLLQCWFVARVSTLPGVLMTIPWAVISGFLFNVLLTDIGAADFSGTGCAIFTVNQSAPIVTVLVVAGAGATAMCADLGARTIREELDALRVMGINPIQALAAPRVLAATTVSLALNSVVTATGLIGAFFCSVFLMHVSAGAWVTGLTTLTHTVDVVISMIKATLFGLMAGLIACYKGMSVGGGPAGVGRAVNETVVFAFIVLFVINIVVTAVGIPFMVS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

part of mce3operon,
Sanger Rv1964, Tigr MT2016

813 bp forward orf at  [06:00]

-> Mtbook page 682

part of mce3operon

Function

Classification IV. A
Category IV. Other
Class A. Virulence

Protein

271 aminoacids, 28,1 kDa

>Rv1965 MTAAKALVSEWNRMGSQMRFFVGTLAGIPDALMHYRGELLRVIAQMGLGTGVLAVIGGTVAIVGFLAMTTGAIVAVQGYNQFASVGVEALTGFASAFFNTREIQPGTVMVALAATVGAGTTAALGAMRINEEIDALEVIGIRSISYLASTRVLAGVVVAVPLFCVGLMTAYLAARVGTTAIYGQGSGVYDHYFNTFLRPTDVLWSSVEVVVVALMIMLVCTYYGYAAHGGPAGVGEAVGRAVRASMVVASIAILVMTLAIYGQSPNFHLAT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

part of mce3operon,
Sanger Rv1965, Tigr MT2017

1275 bp forward orf at  [06:00]

-> Mtbook page 682

mce3

cell invasion protein

Function

Classification IV. A
Category IV. Other
Class A. Virulence

Protein

425 aminoacids, 45 kDa

>Rv1966 MRRGPGRHRLHDAWWTLILFAVIGVAVLVTAVSFTGSLRSTVPVTLAADRSGLVMDSGAKVMMRGVQVGRVAQIGRIEWAQNGASLRLEIDPDQIRYIPANVEAQISATTAFGAKFVDLVMPQNPSRARLSAGAVLHSKNVSTEINTVFENVVDLLNMIDPLKLNAVLTAVADAVRGQGERIGQATTDLNEVLEALNARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVVNHSTQLDALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKYNPEYTCFLQGAKWYLDNGGYAAWGGADGRTLQLDVALLFGNDPYVYPDNLPVVAAKGGPGGRPGCGPLPDATHNFPVRQLVTNTGWGTGLDIRPNPGIGHPCWANYFPVTRAVPEPPSIRQCIPGPAIGPNPAAGEQP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: mce3, mce3 and M. tuberculosis,
cell invasion protein,
Sanger Rv1966, Tigr MT2018

1026 bp forward orf at  [06:00]

-> Mtbook page 683

part of mce3operon

Function

Classification IV. A
Category IV. Other
Class A. Virulence

Protein

342 aminoacids, 36,5 kDa

>Rv1967 MRENLGGVVVRLGVFLAVCLLTAFLLIAVFGEVRFGDGKTYYAEFANVSNLRTGKLVRIAGVEVGKVTRISINPDATVRVQFTADNSVTLTRGTRAVIRYDNLFGDRYLALEEGAGGLAVLRPGHTIPLARTQPALDLDALIGGFKPLFRALNPEQVNALSEQLLHAFAGQGPTIGSLLAQSAAVTNTLADRDRLIGQVITNLNVVLGSLGAHTDRLDQAVTSLSALIHRLAQRKTDISNAVAYTNAAAGSVADLLSQARAPLAKVVRETDRVAGIAAADHDYLDNLLNTLPDKYQALVRQGMYGDFFAFYLCDVVLKVNGKGGQPVYIKLAGQDSGRCAPK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

part of mce3operon,
Sanger Rv1967, Tigr MT2019

1230 bp forward orf at  [06:00]

-> Mtbook page 683

part of mce3operon

Function

Classification IV. A
Category IV. Other
Class A. Virulence

Protein

410 aminoacids, 43,7 kDa

>Rv1968 MKSFAERNRLAIGTVGIVVVAAVALAALQYQRLPFFNQGTRVSAYFADAGGLRTGNTVEVSGYPVGKVSSISLDGPGVLVEFKVDTDVRLGNRTEVAIKTKGLLGSKFLDVTPRGDGRLDSPIPIERTTSPYQLPDALGDLAATISGLHTERLSESLATLAQTFADTPAHFRNAIHGVARLAQTLDERDNQLRSLLANAAKATGVLANRTDQIVGLVRDTNVVLAQLRTQSAALDRIWANISAVAEQLRGFIAENRQQLRPALDKLNGVLAIVENRKERVRQAIPLINTYVMSLGESLSSGPFFKAYVVNLLPGQFVQPFISAAFSDLGLDPATLLPSQLTDPPTGQPGTPPLPMPYPRTGQGGEPRLTLPDAITGNPGDPRYPYRPEPPAPPPGGPPPGPPAQQPGDQP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

part of mce3operon,
Sanger Rv1968, Tigr MT2020

1270 bp forward orf at  [06:01]

-> Mtbook page 683

part of mce3operon

Function

Classification IV. A
Category IV. Other
Class A. Virulence

Protein

423,333333333333 aminoacids, 44,4 kDa

>Rv1969 VTTKLRRARSVLATALVLVAGVILAMRTADAAARTTVVAYFDNSNGVFAGDDVLIRGVPVGKIVKIEPQPLRAKISFWFDRKYRVPADAAAAILSPQLVTGRAIQLTPPYAGGPTMADGTVIPQERTVVPVEWDDLRAQLQRLTALLQPTRPGGVSTLGALINTAADNLRGQGATIRDTIIKLSQAISALGDHSKDIFSTVTNLSTLVTALHDSADLLERLNHNLAAVTSLLADGPDKIGQAAEDLNAVVADVGSFAAEHREAIGTASDKLASITTALVDSLDDIKQTLHISPTVLQNFNNIFEPANGALTGALAGNNMANPIAFLCGAIQAASRLGGEQAAKLCVQYLAPIVKNRQYNYPPLGANLFVGAQARPNEVTYSEDWLRPDYVAPVADTPPDPAAAVTVDPATGLRGMMMPPGGGS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

part of mce3operon,
Sanger Rv1969, Tigr MT2021

1131 bp forward orf at  [06:01]

-> Mtbook page 684

lprM

part of mce3 operon

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

377 aminoacids, 40,2 kDa

>Rv1970 VRIGLTLVMIAAVVASCGWRGLNSLPLPGTQGNGPGSFAVQAQLPDVNNIQPNSRVRVADVTVGHVTKIERQGWHALVTMRLDGDVDLPANATAKIGTTSLLGSYHIELAPPKGEARQGKLRDGSLIALSHGSAYPSTEQTLAALSLVLNGGGLGQVQDITEALSTAFAGREHDLRGLIGQLDTFTAYLNNQSGDIIAATDSLNRLVGKFADQQPVFDRALATIPDALAVLADERDTLVEAAEQLSKFSALTVDSVNKTTANLVTELRQLGPVLESLANSGPALTRSLSLLATFPFPNETFQNFQRGEYANLTAIVDLTLSRIDQGLLTGTRWECHLTQLELQWGRTIGQFPSPCTAGYRGTPGNPLTIAYRWDQGP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lprM, lprM and M. tuberculosis,
part of mce3 operon,
Sanger Rv1970, Tigr MT2022

1311 bp forward orf at  [06:01]

-> Mtbook page 684

part of mce3operon

Function

Classification IV. A
Category IV. Other
Class A. Virulence

Protein

437 aminoacids, 46,7 kDa

>Rv1971 MLHLPRRVIVQLAVFTVIAVGVLAITFLHFVRLPAMLFGVGRYTVTMELVEAGGLYRTGNVTYRGFEVGRVAAVRLTDTGVQAVLALKSGIDIPSDLKAEVHSHTAIGETYVELLPRNAASPPLKNGDVIALADTSVPPDINDLLSAANTALEAIPHENLQTVIDESYTAVAGLGLELSRLIKGSAELAIDARANLDPLVALIDRAGPVLDSQTHTSDAIAAWAAQLAAVTGQLQTHDSAVGDLIDRGGPALGETRQLLERLQPTVPILLANLVSVGQVALTYHNDIEQLLVVFPMAIAAEQAGILANLNTKQAYRGQYLSFNLNLNLPPPCTTGFLPAQQRRIPTFEDYPDRPAGDLYCRVPQDSPFNVRGARNIPCETVPGKRAPTVKLCESDAPYLPLNDGYNWKGDPNATVPGLGSGQDIPQTWQTMLLPPGS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

part of mce3operon,
Sanger Rv1971, Tigr MT2023

573 bp forward orf at  [06:01]

-> Mtbook page 685

Function

unknown

Protein

191 aminoacids, 20,6 kDa

>Rv1972 MSVAVDSDAEDDAVSEIAEAAGVSPAPAKPSMSAPRRMLLFGLVVVVALAVLLCCWGFRVQRARHAQDQRGHFLQAARQCALNLTTIDWRNAEADVRRILDGATGEFYNDFAQRSQPFVEVLRHAKASTVGTITEAGLQTQTADTAQALVAVSVQTSNAGEADPVPRAWRMRITVQRVGDRVKVSDVGFVP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1972, Tigr MT2024

480 bp forward orf at  [06:01]

-> Mtbook page 685

Function

unknown

Protein

160 aminoacids, 16,8 kDa

>Rv1973 VSWSRVIAYGLLPGLALALTCGAGLLKWQDGAVRDAAVARAESVRAATDGTTALLSYRPDTVQHDLESARSRLTGTFLDAYTQLTHDVVIPGAQQKQISAVATVAAAASVSTSADRAVVLLFVNQTITVGKDAPTTAASSVRVTLDNINGRWLISQFEPI*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1973

375 bp forward orf at  [06:01]

-> Mtbook page 685

Function

unknown

Protein

125 aminoacids, 13,5 kDa

>Rv1974 VQRQSLMPQQTLAAGVFVGALLCGVVTAAVPPHARADVVAYLVNVTVRPGYNFANADAALSYGHGLCEKVSRGRPYAQIIADVKADFDTRDQYQASYLLSQAVNELCPALIWQLRNSAVDNRRSG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1974, Tigr MT2025

663 bp forward orf at  [06:02]

-> Mtbook page 685

Function

unknown

Protein

221 aminoacids, 23,7 kDa

>Rv1975 MSRRASATCALSATTAVAIMAAPAARADDKRLNDGVVANVYTVQRQAGCTNDVTINPQLQLAAQWHTLDLLNNRHLNDDTGSDGSTPQDRAHAAGFRGKVAETVAINPAVAISGIELINQWYYNPAFFAIMSDCANTQIGVWSENSPDRTVVVAVYGQPDRPSAMPPRGAVTGPPSPVAAQENVPIDPSPDYDASDEIEYGINWLPWILRGVYPPPAMPPQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1975, Tigr MT2026

405 bp reverse orf at  [06:02]

-> Mtbook page 685

Function

unknown

Protein

135 aminoacids, 15 kDa

>Rv1976c VRWIVDGMNVIGSRPDGWWRDRHRAMVMLVERLEGWAITKARGDDVTVVFERPPSTAIPSSVVEVAHAPKAAANSADDEIVRLVRSGAQPQEIRVVTSDKALTDRVRDLGAAVYPAERFRDLIDPRGSNAARRTQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1976c, Tigr MT2028

1044 bp forward orf at  [06:02]

-> Mtbook page 686

probable zinc metallopeptidase

Function

Classification II. B.3
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 3. Proteins, peptides and glycopeptides

Protein

348 aminoacids, 38,3 kDa

>Rv1977 MSQTPATTRKTFPEISSRAWEHPADRTALSALRRLKGFDQILKLMSGMLRERQHRLLYLASAARVGPRQFADLDALLDECVDVLDASAKPELYVMQSPIADAFTIGMGKPFTVITSGLYDLVTHDEMRFVMGHELGHALSGHAVYRTMMMHLLRLARSFGVLPVGGWALRAIVAALLEWQRKSELSGDRAGLLCAQDLDTALRVEMKLAGGCRLDKLDSEAFLAQAREYETSGDMRDGVLKLLNLELQTHPFSVLRAAALTHWVDTGGYAKVIAGEYPRRADDGNAKFADDLGAAARYYRDGFDQSNDPLIKGIRDGFGGIVEGVGRAASNAADSLGRKITEWRQPSK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable zinc metallopeptidase,
Sanger Rv1977, Tigr MT2029

846 bp forward orf at  [06:02]

-> Mtbook page 686

similar to methyltransferases

Function

Classification IV. H
Category IV. Other
Class H. Miscellaneous transferases (61)

Protein

282 aminoacids, 30,6 kDa

>Rv1978 MGEANIREQAIATMPRGGPDASWLDRRFQTDALEYLDRDDVPDEVKQKIIGVLDRVGTLTNLHEKYARIALKLVSDIPNPRILELGAGHGKLSAKILELHPTATVTISDLDPTSVANIAAGELGTHPRARTQVIDATAIDGHDHSYDLAVFALAFHHLPPTVACKAIAEATRVGKRFLIIDLKRQKPLSFTLSSVLLLPLHLLLLPWSSMRSSMHDGFISALRAYSPSALQTLARAADPGMQVEILPAPTRLFPPSLAVVFSRSSSAPTESSECSADRQPGE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

similar to methyltransferases,
Sanger Rv1978, Tigr MT2030

1443 bp reverse orf at  [06:02]

-> Mtbook page 686

unknown permease

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

481 aminoacids, 51,1 kDa

>Rv1979c VVGPRTRGYAIHKLGFCSVVMLGINSIIGAGIFLTPGEVIGLAGPFAPMAYVLAGIFAGVVAIVFATAARYVRTNGASYAYTTAAFGRRIGIYVGVTHAITASIAWGVLASFFVSTLLRVAFPDKAWADAEQLFSVKTLTFLGFIGVLLAINLFGNRAIKWANGTSTVGKAFALSAFIVGGLWIITTQHVNNYATAWSAYSATPYSLLGVAEIGKGTFSSMALATIVALYAFTGFESIANAAEEMDAPDRNLPRAIPIAIFSVGAIYLLTLTVAMLLGSNKIAASDDTVKLAAAIGNATFRTIIVVGALISMFGINVAASFGAPRLWTALADSGVLPTRLSRKNQYDVPMVSFAITASLALAFPLALRFDNLHLTGLAVIARFVQFIIVPIALIALARSQAVEHAAVRRNAFTDKVLPLVAIVVSVGLAVSYDYRCIFLVRGGPNYFSIALIVITFVVVPAMAYLHYYRIIRRVGDRPSTR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

unknown permease,
Sanger Rv1979c, Tigr MT2031

684 bp reverse orf at  [06:02]

-> Mtbook page 687

mpt64

secreted immunogenic protein Mpb64/Mpt64

Function

Classification II. C.2
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 2. Surface polysaccharides, lipopolysaccharides, proteins and antigens

Protein

228 aminoacids, 24,8 kDa

>Rv1980c VRIKIFMLVTAVVLLCCSGVATAAPKTYCEELKGTDTGQACQIQMSDPAYNINISLPSYYPDQKSLENYIAQTRDKFLSAATSSTPREAPYELNITSATYQSAIPPRGTQAVVLKVYQNAGGTHPTTTYKAFDWDQAYRKPITYDTLWQADTDPLPVVFPIVQGELSKQTGQQVSIAPNAGLDPVNYQNFAVTNDGVIFFFNPGELLPEAAGPTQVLVPRSAIDSMLA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: mpt64, mpt64 and M. tuberculosis,
secreted immunogenic protein Mpb64/Mpt64,
Sanger Rv1980c, Tigr MT2032

966 bp reverse orf at  [06:03]

-> Mtbook page 687

nrdF

ribonucleotide reductase small subunit

Function

Classification I. F.3
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 3. 2'-deoxyribonucleotide metabolism

Protein

322 aminoacids, 36,6 kDa

>Rv1981c MTGKLVERVHAINWNRLLDAKDLQVWERLTGNFWLPEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLDTAQATVGAVAMIDDAVTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQRKAQIIVDYYRGDDALKRKASSVMLESFLFYSGFYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKCQRGLADLTDAERADHREYTCELLHTLYANEIDYAHDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAVRAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDWDF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: nrdF, nrdF and M. tuberculosis,
ribonucleotide reductase small subunit,
Sanger Rv1981c, Tigr MT2033

417 bp reverse orf at  [06:03]

-> Mtbook page 687

Function

unknown

Protein

139 aminoacids, 14,7 kDa

>Rv1982c MIVDTSAVVALVQGERPHATLVAAALAGAHSPVMSAPTVAECLIVLTARHGPVARTIFERLRSEIGLSVSSFTAEHAAATQRAFLRYGKGRHRAALNFGDCMTYATAQLGHQPLLAVGNDFPQTDLEFRGVVGYWPGVA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1982c, Tigr MT2034

1674 bp forward orf at  [06:03]

-> Mtbook page 688

PE_PGRS

Function

Classification IV. C.1.b
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup b

Protein

558 aminoacids, 53,7 kDa

>Rv1983 VSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGVDRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE_PGRS, PE_PGRS and M. tuberculosis,
Sanger Rv1983, Tigr MT2036

651 bp reverse orf at  [06:03]

-> Mtbook page 688

probable secreted protein

Function

Classification II. C.2
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 2. Surface polysaccharides, lipopolysaccharides, proteins and antigens

Protein

217 aminoacids, 21,8 kDa

>Rv1984c MTPRSLVRIVGVVVATTLALVSAPAGGRAAHADPCSDIAVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGVYAVNYPASDDYRASASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTSAMPPAVADHVAAVALFGEPSSGFSSMLWGGGSLPTIGPLYSSKTINLCAPDDPICTGGGNIMAHVSYVQSGMTSQAATFAANRLDHAG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable secreted protein,
Sanger Rv1984c, Tigr MT2037

909 bp reverse orf at  [06:03]

-> Mtbook page 688

transcriptional regulator (LysR family)

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

303 aminoacids, 32,8 kDa

>Rv1985c MVDPQLDGPQLAALAAVVELGSFDAAAERLHVTPSAVSQRIKSLEQQVGQVLVVREKPCRATTAGIPLLRLAAQTALLESEALAEMGGNASLKRTRITIAVNADSMATWFSAVFDGLGDVLLDVRIEDQDHSARLLREGVAMGAVTTERNPVPGCRVHPLGEMRYLPVASRPFVQRHLSDGFTAAAAAKAPSLAWNRDDGLQDMLVRKAFRRAITRPTHFVPTTEGFTAAARAGLGWGMFPEKLAASPLADGSFVRVCDIHLDVPLYWQCWKLDSPIIARITDTVRAAASGLYRGQQRRRRPG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

transcriptional regulator (LysR family),
Sanger Rv1985c, Tigr MT2039

597 bp forward orf at  [06:03]

-> Mtbook page 689

membrane protein, LYSE/YGGA family

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

199 aminoacids, 20,7 kDa

>Rv1986 VNSPLVVGFLACFTLIAAIGAQNAFVLRQGIQREHVLPVVALCTVSDIVLIAAGIAGFGALIGAHPRALNVVKFGGAAFLIGYGLLAARRAWRPVALIPSGATPVRLAEVLVTCAAFTFLNPHVYLDTVVLLGALANEHSDQRWLFGLGAVTASAVWFATLGFGAGRLRGLFTNPGSWRILDGLIAVMMVALGISLTVT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

membrane protein, LYSE/YGGA family,
Sanger Rv1986, Tigr MT2040

426 bp forward orf at  [06:04]

-> Mtbook page 689

probable secreted protein

Function

Classification II. C.2
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 2. Surface polysaccharides, lipopolysaccharides, proteins and antigens

Protein

142 aminoacids, 14,9 kDa

>Rv1987 MAGLNIYVRRWRTALHATVSALIVAILGLAITPVASAATARATLSVTSTWQTGFIARFTITNSSTAPLTDWKLEFDLPAGESVLHTWNSTVARSGTHYVLSPANWNRIIAPGGSATGGLRGGLTGSYSPPSSCLLNGQYPCT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable secreted protein,
Sanger Rv1987, Tigr MT2041

537 bp forward orf at  [06:04]

-> Mtbook page 689

possible rRNAmethyltransferase

Function

Classification IV. H
Category IV. Other
Class H. Miscellaneous transferases (61)

Protein

179 aminoacids, 19,6 kDa

>Rv1988 VSALGRSRRAWGWHRLHDEWAARVVSAAAVRPGELVFDIGAGEGALTAHLVRAGARVVAVELHPRRVGVLRERFPGITVVHADAASIRLPGRPFRVVANPPYGISSRLLRTLLAPNSGLVAADLVLQRALVCKFASRNARRFTLTVGLMLPRRAFLPPPHVDSAVLVVRRRKCGDWQGR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible rRNAmethyltransferase,
Sanger Rv1988, Tigr MT2042

558 bp reverse orf at  [06:04]

-> Mtbook page 690

Function

unknown

Protein

186 aminoacids, 20,2 kDa

>Rv1989c VSDALDEGLVQRIDARGTIEWSETCYRYTGAHRDALSGEGARRFGGRWNPPLLFPAIYLADSAQACMVEVERAAQAASTTAEKMLEAAYRLHTIDVTDLAVLDLTTPQAREAVGLENDDIYGDDWSGCQAVGHAAWFLHMQGVLVPAAGGVGLVVTAYEQRTRPGQLQLRQSVDLTPALYQELRAT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1989c, Tigr MT2043

339 bp reverse orf at  [06:04]

-> Mtbook page 690

putative transcriptional regulator

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

113 aminoacids, 12,5 kDa

>Rv1990c MGVNVLASTVSGAIERLGLTYEEVGDIVDASPRSVARWTAGQVVPQRLNKQRLIELAYVADALAEVLPRDQANVWMFSPNRLLEHRKPADLVRDGEYQRVLALIDAMAEGVFV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative transcriptional regulator,
Sanger Rv1990c, Tigr MT2044

342 bp reverse orf at  [06:04]

-> Mtbook page 690

Function

unknown

Protein

114 aminoacids, 12,2 kDa

>Rv1991c VVISRAEIYWADLGPPSGSQPAKRRPVLVIQSDPYNASRLATVIAAVITSNTALAAMPGNVFLPATTTRLPRDSVVNVTAIVTLNKTDLTDRVGEVPASLMHEVDRGLRRVLDL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1991c, Tigr MT2046

2313 bp reverse orf at  [06:04]

-> Mtbook page 690

ctpG

probable cation transport ATPase

Function

Classification III. A.2
Category III. Cell processes
Class A. Transport/binding proteins
Group 2. Cations

Protein

771 aminoacids, 79,3 kDa

>Rv1992c VTTVVDAEVQLTVVSDAAGRMRVQATGFQFDAGRAVAIEDTVGKVAGVQAVHAYPRTASIVIWYSRAICDTAAILSAIIDAETVPAAAVPAYASRSASNRKAGVVQKIIDWSTRTLSGVRRDVAAQPSGETSDACCDGEDNEDREPEQLWQVAKLRRAAFSGVLLTASLVAAWAYPLWPVVLGLKALALAVGASTFVPSSLKRLAEGRVGVGTLMTIAALGAVALGELGEAATLAFLFSISEGLEEYATARTRRGLRALLSLVPDQATVLREGTETIVASTELHVGDQMIVKPGERLATDGIIRAGRTALDVSAITGESVPVEVGPGDEVFAGSINGLGVLQVGVTATAANNSLARIVHIVEAEQVRKGASQRLADCIARPLVPSIMIAAALIAGTGSVLGNPLVWIERALVVLVAAAPCALAIAVPVTVVASIGAASRLGVLIKGGAALETLGTIRAVALDKTGTLTANRPVVIDVATTNGATREEVLAVAAALEARSEHPLAVAVLAATQATTAASDVQAVPGAGLIGRLDGRVVRLGRPGWLDAAELADHVACMQQAGATAVLVERDQQLLGAIAVRDELRPEAAEVVAGLRTGGYQVTMLTGDNHATAAALAAQAGIEQVHAELRPEDKAHLVAQLRARQPTAMVGDGVNDAPALAAADLGIAMGAMGTDVAIETADVALMGQDLRHLPQALDHARRSRQIMVQNVGLSLSIITVLMPLALFGILGLAAVVLVHEFTEVIVIANGVRAGRIKPLAGPPKTPDRTIPG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ctpG, ctpG and M. tuberculosis,
probable cation transport ATPase,
Sanger Rv1992c, Tigr MT2048