1269 bp forward orf at  [05:33]

-> Mtbook page 631

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

423 aminoacids, 41,5 kDa

>Rv1801 MDFGLLPPEINSGRMYTGPGPGPMLAAATAWDGLAVELHATAAGYASELSALTGAWSGPSSTSMASAAAPYVAWMSATAVHAELAGAQARLAIAAYEAAFAATVPPPVIAANRAQLMVLIATNIFGQNTPAIMMTEAQYMEMWAQDAAAMYGYAGSSATASRMTAFTEPPQTTNHGQLGAQSSAVAQTAATAAGGNLQSAFPQLLSAVPRALQGLALPTASQSASATPQWVTDLGNLSTFLGGAVTGPYTFPGVLPPSGVPYLLGIQSVLVTQNGQGVSALLGKIGGKPITGALAPLAEFALHTPILGSEGLGGGSVSAGIGRAGLVGKLSVPQGWTVAAPEIPSPAAALQATRLAAAPIAATDGAGALLGGMALSGLAGRAAAGSTGHPIGSAAAPAVGAAAAAVEDLATEANIFVIPAMDD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv1801, Tigr MT1850

1389 bp forward orf at  [05:33]

-> Mtbook page 631

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

463 aminoacids, 46 kDa

>Rv1802 MDFGVLPPEINSGRMYAGPGSGPMLAAAAAWDGLATELQSTAADYGSVISVLTGVWSGQSSGTMAAAAAPYVAWMSATAALAREAAAQASAAAAAYEAAFAATVPPPVVAANRAELAVLAATNIFGQNTGAIAAAEARYAEMWAQDAAAMYGYAGSSSVATQVTPFAAPPPTTNAAGLATQGVAVAQAVGASAGNARSLVSEVLEFLATAGTNYNKTVASLMNAVTGVPYASSVYNSMLGLGFAESKMVLPANDTVISTIFGMVQFQKFFNPVTPFNPDLIPKSALGAGLGLRSAISSGLGSTAPAISAGASQAGSVGGMSVPPSWAAATPAIRTVAAVFSSTGLQAVPAAAISEGSLLSQMALASVAGGALGGAAARATGGFLGGGRVTAVKKSLKDSDSPDKLRRVVAHMMEKPESVQHWHTDEDGLDDLLAELKKKPGIHAVHMAGGNKAEIAPTISESG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv1802, Tigr MT1851

1917 bp reverse orf at  [05:33]

-> Mtbook page 632

PE_PGRS

Function

Classification IV. C.1.b
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup b

Protein

639 aminoacids, 54,9 kDa

>Rv1803c VWTSQMIVAPAFVDAAAKDLATIGSAISRANAEALVPITALLPAGADDVSAAIAALFATHGQAYQELSAHAVAFHEQFVQLMSAGAAQYASAEAANSSPLQIVGQTALDAINSPVQTLTGRPLIGNGANGVAGTGQNGGDGGWLYGNGGNGGSGGTGQNGGNGGSAGLWGSGGNGGQGGAGANGAAGQPGKAGGSGGNGGAGGWIYGHGGHGGAGGNGGNATAPGGASAGFDGGAGGNGGSGGRGGLLFGNGGNGSVGGMGGQGTNDTAGDSAGSGGLGGNGGNGAQGGWLIGNGGQGGDSGAGGGTDSTQTGVMNGASGGSAGIAGNGGDAGLVGNGGAGGNGGNGAAGSALGTTIFGGSGGVGGSGGDGGNGGWLFGSGASGGNGGQGGDAGTNGFAGFGGSAGGGGWVGAVNFGPISVQGFGLFGHGGDGGNGGDVGAGSLSIQFGASGGDGGQGGVLYGNGGNGGNAGSGGGTGFEGSAGQGGAAILIGNGGAGGNGATGGTGVGNIIQEAGGDGSDGGAGGSGGLLFGSGGAGGIGGAGGVGGSGNDGGNGGDGGQGGASGLGIGNGGPGGSGGTGGAGGTGGSAGTGGAGGDGGNAALLIGTGGDGGDGVPPAPGGQGGKGGLIGLPGQNGQP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE_PGRS, PE_PGRS and M. tuberculosis,
Sanger Rv1803c, Tigr MT1853

324 bp reverse orf at  [05:34]

-> Mtbook page 632

Function

unknown

Protein

108 aminoacids, 11,2 kDa

>Rv1804c MRVVSTLLSIPLMIGLAVPAHAGPSGDDAVFLASLERAGITYSHPDQAIASGKAVCALVESGESGLQVVNELRTRNPGFSMDGCCKFAAISAHVYCPHQITKTSVSAK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1804c

345 bp reverse orf at  [05:34]

-> Mtbook page 633

Function

unknown

Protein

115 aminoacids, 12,7 kDa

>Rv1805c MTASVVATSRERHSHKAAKQRACEITDFEPEGRFRVRKRRRGRIGTKRSSISDTDYRRDSFRSHLLTAGAHGDADAQHKGMTAQQTTELGTPLVRALAPHGVSGRSSRKPLGLNP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1805c, Tigr MT1854

297 bp forward orf at  [05:34]

-> Mtbook page 633

PE

Function

Classification IV. C.1.a
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup a

Protein

99 aminoacids, 9,8 kDa

>Rv1806 MAFVLVCPDALAIAAGQLRHVGSVIAARNAVAAPATAELAPAAADEVSALTATQFNFHAAMYQAVGAQAIAMNEAFVAMLGASADSYAATEAANIIAVS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE, PE and M. tuberculosis,
Sanger Rv1806, Tigr MT1855

1209 bp forward orf at  [05:34]

-> Mtbook page 633

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

403 aminoacids, 39,2 kDa

>Rv1807 MTAALDFATLPPEINSARMYSGAGSAPMLAAASAWHGLSAELRASALSYSSVLSTLTGEEWHGPASASMTAAAAPYVAWMSVTAVRAEQAGAQAEAAAAAYEAAFAATVPPPVIEANRAQLMALIATNVLGQNAPAIAATEAQYAEMWSQDAMAMYGYAGASAAATQLTPFTEPVQTTNASGLAAQSAAIAHATGASAGAQQTTLSQLIAAIPSVLQGLSSSTAATFASGPSGLLGIVGSGSSWLDKLWALLDPNSNFWNTIASSGLFLPSNTIAPFLGLLGGVAAADAAGDVLGEATSGGLGGALVAPLGSAGGLGGTVAAGLGNAATVGTLSVPPSWTAAAPLASPLGSALGGTPMVAPPPAVAAGMPGMPFGTMGGQGFGRAVPQYGFRPNFVARPPAAG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv1807, Tigr MT1856

1227 bp forward orf at  [05:34]

-> Mtbook page 633

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

409 aminoacids, 39,9 kDa

>Rv1808 LDFGALPPEINSGRMYAGPGSGPLLAAAAAWDALAAELYSAAASYGSTIEGLTVAPWMGPSSITMAAAVAPYVAWISVTAGQAEQAGAQAKIAAGVYETAFAATVPPPVIEANRALLMSLVATNIFGQNTPAIAATEAHYAEMWAQDAAAMYGYAGSSATASQLAPFSEPPQTTNPSATAAQSAVVAQAAGAAASSDITAQLSQLISLLPSTLQSLATTATATSASAGWDTVLQSITTILANLTGPYSIIGLGAIPGGWWLTFGQILGLAQNAPGVAALLGPKAAAGALSPLAPLRGGYIGDITPLGGGATGGIARAIYVGSLSVPQGWAEAAPVMRAVASVLPGTGAAPALAAEAPGALFGEMALSSLAGRALAGTAVRSGAGAARVAGGSVTEDVASTTTIIVIPAD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv1808, Tigr MT1857

1404 bp forward orf at  [05:34]

-> Mtbook page 634

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

468 aminoacids, 47,2 kDa

>Rv1809 MDFGLQPPEITSGEMYLGPGAGPMLAAAVAWDGLAAELQSMAASYASIVEGMASESWLGPSSAGMAAAAAPYVTWMSGTSAQAKAAADQARAAVVAYETAFAAVVPPPQIAANRSQLISLVATNIFGQNTAAIAATEAEYGEMWAQDTMAMFGYASSSATASRLTPFTAPPQTTNPSGLAGQAAATGQATALASGTNAVTTALSSAAAQFPFDIIPTLLQGLATLSTQYTQLMGQLINAIFGPTGATTYQNVFVTAANVTKFSTWANDAMSAPNLGMTEFKVFWQPPPAPEIPKSSLGAGLGLRSGLSAGLAHAASAGLGQANLVGDLSVPPSWASATPAVRLVANTLPATSLAAAPATQIPANLLGQMALGSMTGGALGAAAPAIYTGSGARARANGGTPSAEPVKLEAVIAQLQKQPDAVRHWNVDKADLDGLLDRLSKQPGIHAVHVSNGDKPKVALPDTQLGSH*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv1809, Tigr MT1857

354 bp forward orf at  [05:35]

-> Mtbook page 634

Function

unknown

Protein

118 aminoacids, 12,1 kDa

>Rv1810 MQLQRTMGQCRPMRMLVALLLSAATMIGLAAPGKADPTGDDAAFLAALDQAGITYADPGHAITAAKAMCGLCANGVTGLQLVADLRDYNPGLTMDSAAKFAAIASGAYCPEHLEHHPS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1810, Tigr MT1858

702 bp forward orf at  [05:35]

-> Mtbook page 634

mgtC

probable magnesium transport ATPase protein C

Function

Classification III. A.2
Category III. Cell processes
Class A. Transport/binding proteins
Group 2. Cations

Protein

234 aminoacids, 24,8 kDa

>Rv1811 MQTLTVADFALRLAVGVGCGAIIGLERQWRARMAGLRTNALVATGATLFVLYAVATEDSSPTRVASYVVSGIGFLGGGVILREGFNVRGLNTAATLWCSAAVGVLAASGHLVFTLIGTGTIVAVHLLGRPLGRLVDRDNAVEDEGLQPYQVRVICRPKAETYVRAHIVQRTSSNDITLRGIRTGPAGDDNITLTAHLLMVGHTPAKLERLVAELSLQPGVYAVHWYAGEHAQAE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: mgtC, mgtC and M. tuberculosis,
probable magnesium transport ATPase protein C,
Sanger Rv1811, Tigr MT1859

1200 bp reverse orf at  [05:35]

-> Mtbook page 634

probable dehydrogenase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

400 aminoacids, 41,9 kDa

>Rv1812c LTRVVVIGSGFAGLWAALGAARRLDELAVLAGTVDVMVVSNKPFHDIRVRNYEADLSACRIPLGDVLGPAGVAHVTAEVTAIDADGRRVTTSTGASYSYDRLVLASGSHVVKPALPGLAEFGFDVDTYDGAVRLQQHLQGLAGGPLTSAAATVVVVGAGLTGIETACELPGRLHALFARGDGVTPRVVLIDHNPFVGSDMGLSARPVIEQALLDNGVETRTGVSVAAVSPGGVTLSSGERLAAATVVWCAGMRASRLTEQLPVARDRLGRLQVDDYLRVIGVPAMFAAGDVAAARMDDEHLSVMSCQHGRPMGRYAGCNVINDLFDQPLLALRIPWYVTVLDLGSAGAVYTEGWERKVVSQGAPAKTTKQSINTRRIYPPLNGSRADLLAAAAPRVQPRP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable dehydrogenase,
Sanger Rv1812c, Tigr MT1860

429 bp reverse orf at  [05:35]

-> Mtbook page 635

Function

unknown

Protein

143 aminoacids, 15 kDa

>Rv1813c MITNLRRRTAMAAAGLGAALGLGILLVPTVDAHLANGSMSEVMMSEIAGLPIPPIIHYGAIAYAPSGASGKAWHQRTPARAEQVALEKCGDKTCKVVSRFTRCGAVAYNGSKYQGGTGLTRRAAEDDAVNRLEGGRIVNWACN*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1813c, Tigr MT1861

900 bp forward orf at  [05:35]

-> Mtbook page 635

possible C-5 sterol desaturase

Function

Classification I. H.3
Category I. Small-molecule metabolism
Class H. Lipid biosynthesis
Group 3. Acyltransferases, mycoloyltransferases and phospholipid synthesis

Protein

300 aminoacids, 34,9 kDa

>Rv1814 MRDPVLFAIPCFLLLLILEWTAARKLESIETAATGQPRPASGAYLTRDSVASISMGLVSIATTAGWKSLALLGYAAIYAYLAPWQLSAHRWYTWVIAIVGVDLLYYSYHRIAHRVRLIWATHQAHHSSEYFNFATALRQKWNNSGEILMWVPLPLMGLPPWMVFCSWSLNLIYQFWVHTERIDRLPRWFEFVFNTPSHHRVHHGMDPVYLDKNYGGILIIWDRLFGSFQPELFRPHYGLTKRVDTFNIWKLQTREYVAIVRDWRSATRLRDRLGYVFGPPGWEPRTIDKSNAAASLVTSR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible C-5 sterol desaturase,
Sanger Rv1814, Tigr MT1862

663 bp forward orf at  [05:35]

-> Mtbook page 636

Function

unknown

Protein

221 aminoacids, 22,8 kDa

>Rv1815 VVRLVPRAFAATVALLAAGFSPATASADPVLVFPGMEIRQDNHVCTLGYVDPALKIAFTAGHCRGGGAVTSRDYKVIGHLRAIRDNTPSGSTVATHELIADYEAIVLADDVTASNILPSGRALESRPGVVLHPGQAVCHFGVSTGETCGTVESVNNGWFTMSHGVLSEKGDSGGPVYLAPDGGPAQIVGIFNSVWGGFPAAVSWRSTSEQVHADLGVTPLA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1815, Tigr MT1863

702 bp forward orf at  [05:35]

-> Mtbook page 636

putative transcriptional regulator

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

234 aminoacids, 25,3 kDa

>Rv1816 LCQTCRVGKRRDAREQIEAKIVELGRRQLLDHGAAGLSLRAIARNLGMVSSAVYRYVSSRDELLTLLLVDAYSDLADTVDRARDDTVADSWSDDVIAIARAVRGWAVTNPARWALLYGSPVPGYHAPPDRTAGVATRVVGAFFDAIAAGIATGDIRLTDDVAPQPMSSDFEKIRQEFGFPGDDRVVTKCFLLWAGVVGAISLEVFGQYGADMLTDPGVVFDAQTRLLVAVLAEH*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative transcriptional regulator,
Sanger Rv1816, Tigr MT1864

1461 bp forward orf at  [05:36]

-> Mtbook page 636

flavoprotein

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

487 aminoacids, 51 kDa

>Rv1817 MSTDIPATVSAETVTSWSDDVDVTVIGFGIAGGCAAVSAAAAGARVLVLERAAAAGGTTALAGGHFYLGGGTTVQLATGHPDSPEEMYKYLVAVSREPDHDKIRAYCDGSVEHFNWLEGLGFQFERSYFPGKAVIQPNTEGLMFTGNEKVWPFLELAVPAPRGHKVPVPGDTGGAAMVIDLLLKRAASLGIQIRYETGATELIVDGTGKVTGVMWKRFSETGAIKAKSVIIAAGGFVMNPDMVAKYTPKLAEKPFVLGNTYDDGLGIRLGVSAGGATQHMDQMFITAPPYPPSILLTGIIVNKLGQRFVAEDSYHSRTAGFIMEQPDSAAYLIVDEAHLEHPKMPLVPLIDGWETVVEMEAALGIPPGNLAATLDRYNAYAARGADPDFHKQPEFLAAQDNGPWGAFDMSLGKAMYAGFTLGGLATSVDGQVLRDDGAVVAGLYAVGACASNIAQDGKGYASGTQLGEGSFFGRRAGAHAAARAQGM*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

flavoprotein,
Sanger Rv1817, Tigr MT1865

1494 bp reverse orf at  [05:36]

-> Mtbook page 637

PE_PGRS

Function

Classification IV. C.1.b
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup b

Protein

498 aminoacids, 40,8 kDa

>Rv1818c MSFVVTIPEALAAVATDLAGIGSTIGTANAAAAVPTTTVLAAAADEVSAAMAALFSGHAQAYQALSAQAALFHEQFVRALTAGAGSYAAAEAASAAPLEGVLDVINAPALALLGRPLIGNGANGAPGTGANGGDGGILIGNGGAGGSGAAGMPGGNGGAAGLFGNGGAGGAGGNVASGTAGFGGAGGAGGLLYGAGGAGGAGGRAGGGVGGIGGAGGAGGNGGLLFGAGGAGGVGGLAADAGDGGAGGDGGLFFGVGGAGGAGGTGTNVTGGAGGAGGNGGLLFGAGGVGGVGGDGVAFLGTAPGGPGGAGGAGGLFGVGGAGGAGGIGLVGNGGAGGSGGSALLWGDGGAGGAGGVGSTTGGAGGAGGNAGLLVGAGGAGGAGALGGGATGVGGAGGNGGTAGLLFGAGGAGGFGFGGAGGAGGLGGKAGLIGDGGDGGAGGNGTGAKGGDGGAGGGAILVGNGGNGGNAGSGTPNGSAGTGGAGGLLGKNGMNGLP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE_PGRS, PE_PGRS and M. tuberculosis,
Sanger Rv1818c, Tigr MT1866

1917 bp reverse orf at  [05:36]

-> Mtbook page 637

probable multidrug resistance pump

Function

Classification III. A.6
Category III. Cell processes
Class A. Transport/binding proteins
Group 6. Efflux proteins

Protein

639 aminoacids, 71,3 kDa

>Rv1819c LGPKLFKPSIDWSRAFPDSVYWVGKAWTISAICVLAILVLLRYLTPWGRQFWRITRAYFVGPNSVRVWLMLGVLLLSVVLAVRLNVLFSYQGNDMYTALQKAFEGIASGDGTVKRSGVRGFWMSIGVFSVMAVLHVTRVMADIYLTQRFIIAWRVWLTHHLTQDWLDGRAYYRDLFIDETIDNPDQRIQQDVDIFTAGAGGTPNAPSNGTASTLLFGAVQSIISVISFTAILWNLSGTLNIFGVSIPRAMFWTVLVYVFVATVISFIIGRPLIWLSFRNEKLNAAFRYALVRLRDAAEAVGFYRGERVEGTQLQRRFTPVIDNYRRYVRRSIAFNGWNLSVSQTIVPLPWVIQAPRLFAGQIDFGDVGQTATSFGNIHDSLSFFRNNYDAFASFRAAIIRLHGLVDANEKGRALPAVLTRPSDDESVELNDIEVRTPAGDRLIDPLDVRLDRGGSLVITGRSGAGKTTLLRSLAELWPYASGTLHRPGGENETMFLSQLPYVPLGTLRDVVCYPNSAAAIPDATLRDTLTKVALAPLCDRLDEERDWAKVLSPGEQQRVAFARILLTKPKAVFLDESTSALDTGLEFALYQLLRSELPDCIVISVSHRPALERLHENQLELLGGGQWRLAPVEAAPAEV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable multidrug resistance pump,
Sanger Rv1819c, Tigr MT1867

1641 bp forward orf at  [05:36]

-> Mtbook page 638

ilvG

acetolactate synthase II

Function

Classification I. D.7
Category I. Small-molecule metabolism
Class D. Amino acid biosynthesis
Group 7. Branched amino acid family

Protein

547 aminoacids, 57,5 kDa

>Rv1820 MSTDTAPAQTMHAGRLIARRLKASGIDTVFTLSGGHLFSIYDGCREEGIRLIDTRHEQTAAFAAEGWSKVTRVPGVAALTAGPGITNGMSAMAAAQQNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVARFAATAQSAENAGLLVDQALQAAVSAPSGVAFVDFPMDHAFSMSSDNGRPGALTELPAGPTPAGDALDRAAGLLSTAQRPVIMAGTNVWWGHAEAALLRLVEERHIPVLMNGMARGVVPADHRLAFSRARSKALGEADVALIVGVPMDFRLGFGGVFGSTTQLIVADRVEPAREHPRPVAAGLYGDLTATLSALAGSGGTDHQGWIEELATAETMARDLEKAELVDDRIPLHPMRVYAELAALLERDALVVIDAGDFGSYAGRMIDSYLPGCWLDSGPFGCLGSGPGYALAAKLARPQRQVVLLQGDGAFGFSGMEWDTLVRHNVAVVSVIGNNGIWGLEKHPMEALYGYSVVAELRPGTRYDEVVRALGGHGELVSVPAELRPALERAFASGLPAVVNVLTDPSVAYPRRSNLA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ilvG, ilvG and M. tuberculosis,
acetolactate synthase II,
Sanger Rv1820, Tigr MT1868

2424 bp forward orf at  [05:37]

-> Mtbook page 638

secA2

SecA, preprotein translocase subunit

Function

Classification III. D
Category III. Cell processes
Class D. Protein and peptide secretion

Protein

808 aminoacids, 88,9 kDa

>Rv1821 VNVHGCPRIAACRCTDTHPRGRPAFAYRWFVPKTTRAQPGRLSSRFWRLLGASTEKNRSRSLADVTASAEYDKEAADLSDEKLRKAAGLLNLDDLAESADIPQFLAIAREAAERRTGLRPFDVQLLGALRMLAGDVIEMATGEGKTLAGAIAAAGYALAGRHVHVVTINDYLARRDAEWMGPLLDAMGLTVGWITADSTPDERRTAYDRDVTYASVNEIGFDVLRDQLVTDVNDLVSPNPDVALIDEADSVLVDEALVPLVLAGTTHRETPRLEIIRLVAELVGDKDADEYFATDSDNRNVHLTEHGARKVEKALGGIDLYSEEHVGTTLTEVNVALHAHVLLQRDVHYIVRDDAVHLINASRGRIAQLQRWPDGLQAAVEAKEGIETTETGEVLDTITVQALINRYATVCGMTGTALAAGEQLRQFYQLGVSPIPPNKPNIREDEADRVYITTAAKNDGIVEHITEVHQRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGAVTVSTQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSVFFSSWEDDVVAANLDHNKLPMATDENGRIVSPRTGSLLDHAQRVAEGRLLDVHANTWRYNQLIAQQRAIIVERRNTLLRTVTAREELAELAPKRYEELSDKVSEERLETICRQIMLYHLDRGWADHLAYLADIRESIHLRALGRQNPLDEFHRMAVDAFASLAADAIEAAQQTFETANVLDHEPGLDLSKLARPTSTWTYMVNDNPLSDDTLSALSLPGVFR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: secA2, secA2 and M. tuberculosis,
SecA, preprotein translocase subunit,
Sanger Rv1821, Tigr MT1869

627 bp forward orf at  [05:37]

-> Mtbook page 639

pgsA2

CDP-diacylglycerol-glycerol-3- phosphate phosphatidyltransferase

Function

Classification I. H.3
Category I. Small-molecule metabolism
Class H. Lipid biosynthesis
Group 3. Acyltransferases, mycoloyltransferases and phospholipid synthesis

Protein

209 aminoacids, 22,9 kDa

>Rv1822 MEPVLTQNRVLTVPNMLSVIRLALIPAFVYVVLSAHANGWGVAILVFSGVSDWADGKIARLLNQSSRLGALLDPAVDRLYMVTVPIVFGLSGIVPWWFVLTLLTRDALLAGTLPLLWSRGLSALPVTYVGKAATFGFMVGFPTILLGQCDPLWSHVLLACGWAFLIWGMYAYLWAFVLYAVQMTMVVRQMPKLKGRAHRPAAQNAGERG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pgsA2, pgsA2 and M. tuberculosis,
CDP-diacylglycerol-glycerol-3- phosphate phosphatidyltransferase,
Sanger Rv1822, Tigr MT1870

921 bp forward orf at  [05:37]

-> Mtbook page 639

Function

unknown

Protein

307 aminoacids, 31,9 kDa

>Rv1823 VAESDRLLGGYDPNAGYSAHAGAQPQRIPVPSLLRALLSEHLDAGYAAVAAERERAAAPRCWQARAVSWMWQALAATLVAAVFAAAVAQARSVAPGVRAAQQLLVASVRSTQAAATTLAQRRSTLSAKVDDVRRIVLADDAEGQRLLARLDVLSLAAASAPVVGPGLTVTVTDPGASPNLSDVSKQRVSGSQQIILDRDLQLVVNSLWESGAEAISIDGVRIGPNVTIRQAGGAILVDNNPTSSPYTILAVGPPHAMQDVFDRSAGLYRLRLLETSYGVGVSVNVGDGLALPAGATRDVKFAKQIGP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1823, Tigr MT1871

363 bp forward orf at  [05:37]

-> Mtbook page 640

small basic protein similar SBP_BACSU

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

121 aminoacids, 12,8 kDa

>Rv1824 MGSDTAWSPARMIGIAALAVGIVLGLVFHPGVPEVIQPYLPIAVVAALDAVFGGLRAYLERIFDPKVFVVSFVFNVLVAALIVYVGDQLGVGTQLSTAIIVVLGIRIFGNTAALRRRLFGA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

small basic protein similar SBP_BACSU,
Sanger Rv1824, Tigr MT1872

876 bp forward orf at  [05:38]

-> Mtbook page 640

Function

unknown

Protein

292 aminoacids, 30,6 kDa

>Rv1825 VSENRPEPVAAETSAATTARHSQADAGAHDAVRRGRHELPADHPRSKVGPLRRTRLTEILRGGRSRLVFGTLAILLCLVLGVAIVTQVRQTDSGDSLETARPADLLVLLDSLRQREATLNAEVIDLQNTLNALQASGNTDQAALESAQARLAALSILVGAVGATGPGVMITIDDPGPGVAPEVMIDVINELRAAGAEAIQINDAHRSVRVGVDTWVVGVPGSLTVDTKVLSPPYSILAIGDPPTLAAAMNIPGGAQDGVKRVGGRMVVQQADRVDVTALRQPKQHQYAQPVK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1825, Tigr MT1873

402 bp forward orf at  [05:38]

-> Mtbook page 640

gcvH

glycine cleavage system H protein

Function

Classification I. C.1
Category I. Small-molecule metabolism
Class C. Central intermediary metabolism
Group 1. General

Protein

134 aminoacids, 14,2 kDa

>Rv1826 VSDIPSDLHYTAEHEWIRRSGDDTVRVGITDYAQSALGDVVFVQLPVIGTAVTAGETFGEVESTKSVSDLYAPISGKVSEVNSDLDGTPQLVNSDPYGAGWLLDIQVDSSDVAALESALTTLLDAEAYRGTLTE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: gcvH, gcvH and M. tuberculosis,
glycine cleavage system H protein,
Sanger Rv1826, Tigr MT1874

486 bp forward orf at  [05:38]

-> Mtbook page 640

Function

unknown

Protein

162 aminoacids, 17,2 kDa

>Rv1827 VTDMNPDIEKDQTSDEVTVETTSVFRADFLSELDAPAQAGTESAVSGVEGLPPGSALLVVKRGPNAGSRFLLDQAITSAGRHPDSDIFLDDVTVSRRHAEFRLENNEFNVVDVGSLNGTYVNREPVDSAVLANGDEVQIGKFRLVFLTGPKQGEDDGSTGGP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1827, Tigr MT1875

741 bp forward orf at  [05:38]

-> Mtbook page 640

Function

unknown

Protein

247 aminoacids, 26,4 kDa

>Rv1828 VSAPDSPALAGMSIGAVLDLLRPDFPDVTISKIRFLEAEGLVTPRRASSGYRRFTAYDCARLRFILTAQRDHYLPLKVIRAQLDAQPDGELPPFGSPYVLPRLVPVAGDSAGGVGSDTASVSLTGIRLSREDLLERSEVADELLTALLKAGVITTGPGGFFDEHAVVILQCARALAEYGVEPRHLRAFRSAADRQSDLIAQIAGPLVKAGKAGARDRADDLAREVAALAITLHTSLIKSAVRDVLHR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1828, Tigr MT1876