708 bp reverse orf at  [04:19]

-> Mtbook page 491

lprG

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

236 aminoacids, 24,5 kDa

>Rv1411c MRTPRRHCRRIAVLAAVSIAATVVAGCSSGSKPSGGPLPDAKPLVEEATAQTKALKSAHMVLTVNGKIPGLSLKTLSGDLTTNPTAATGNVKLTLGGSDIDADFVVFDGILYATLTPNQWSDFGPAADIYDPAQVLNPDTGLANVLANFADAKAEGRDTINGQNTIRISGKVSAQAVNQIAPPFNATQPVPATVWIQETGDHQLAQAQLDRGSGNSVQMTLSKWGEKVQVTKPPVS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lprG, lprG and M. tuberculosis,
lipoprotein,
Sanger Rv1411c, Tigr MT1455

603 bp forward orf at  [04:19]

-> Mtbook page 491

ribC

riboflavin synthase a chain

Function

Classification I. G.9
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 9. Riboflavin

Protein

201 aminoacids, 21,3 kDa

>Rv1412 MFTGIVEERGEVTGREALVDAARLTIRGPMVTADAGHGDSIAVNGVCLTVVDVLPDGQFTADVMAETLNRSNLGELRPGSRVNLERAAALGSRLGGHIVQGHVDATGEIVARCPSEHWEVVRIEMPASVARYVVEKGSITVDGISLTVSGLGAEQRDWFEVSLIPTTRELTTLGSAAVGTRVNLEVDVVAKYVERLMRSAG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ribC, ribC and M. tuberculosis,
riboflavin synthase a chain,
Sanger Rv1412, Tigr MT1456

513 bp forward orf at  [04:19]

-> Mtbook page 491

Function

unknown

Protein

171 aminoacids, 17,6 kDa

>Rv1413 VATIGEVEVFVDHGADDVFITYPLWIGTRQADRLRQLADRARIAVGAGTAEGASNTGARLADAAGAIDVLIEIDSGHHRSGVRAEQVLEVAHAVGEAGLHLVGVFTFPGHSYAPGKPGEAGEQERRALNDAANALVAVGFPISCRSGGSTPTALLTAADGASETSRRLCAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1413, Tigr MT1457

399 bp forward orf at  [04:19]

-> Mtbook page 491

Function

unknown

Protein

133 aminoacids, 14,3 kDa

>Rv1414 VLGDAQQLELGRCAPADIALTVAATVVSRQDCRSGLRRIVLDCGSKILGSDRPAWATGFGRLIDHADARIAALSEHHATVVWPDDAPLPPVGTRLRVIPNHVCLTTNLVDDVAVVRDATLIDRWKVAARGKNH*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1414

1275 bp forward orf at  [04:19]

-> Mtbook page 491

ribA2

probable GTP cyclohydrolase II

Function

Classification I. G.9
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 9. Riboflavin

Protein

425 aminoacids, 46 kDa

>Rv1415 MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGIGTGISASDRATTMRLLADPTSVADDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAHTDELRVFADEHGLALITIADLIEWRRKHEKHIERVAEARIPTRHGEFRAIGYTSIYEDVEHVALVRGEIAGPNADGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAALAMVAREGRGVVLYMRGHEGRGIGLMHKLQAYQLQDAGADTVDANLKLGLPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKLGHDLAGLDDFHESVHLPGEFGGAL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ribA2, ribA2 and M. tuberculosis,
probable GTP cyclohydrolase II,
Sanger Rv1415, Tigr MT1458

462 bp forward orf at  [04:19]

-> Mtbook page 492

ribH

riboflavin synthase b chain

Function

Classification I. G.9
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 9. Riboflavin

Protein

154 aminoacids, 15,9 kDa

>Rv1416 VPDLPSLDASGVRLAIVASSWHGKICDALLDGARKVAAGCGLDDPTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFDYVCDAVTQGLTRVSLDSSTPIANGVLTTNTEEQALDRAGLPTSAEDKGAQATVAALATALTLRELRAHS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ribH, ribH and M. tuberculosis,
riboflavin synthase b chain,
Sanger Rv1416, Tigr MT1459

462 bp forward orf at  [04:19]

-> Mtbook page 492

Function

unknown

Protein

154 aminoacids, 16,4 kDa

>Rv1417 VTAAPNDWDVVLRPHWTPLFAYAAAFLIAVAHVAGGLLLKVGSSGVVFQTADQVAMGALGLVLAGAVLLFARPRLRVGSAGLSVRNLLGDRIVGWSEVIGVSFPGGSRWARIDLADDEYIPVMAIQAVDKDRAVAAMDTVRSLLARYRPDLCAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1417, Tigr MT1460

684 bp forward orf at  [04:19]

-> Mtbook page 492

lprH

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

228 aminoacids, 24,3 kDa

>Rv1418 MACLGRPGCRGWAGASLVLVVVLALAACTESVAGRAMRATDRSSGLPTSAKPARARDLLLQDGDRAPFGQVTQSRVGDSYFTSAVPPECSAALLFKGSPLRPDGSSDHAEAAYNVTGPLPYAESVDVYTNVLNVHDVVWNGFRDVSHCRGDAVGVSRAGRSTPMRLRYFATLSDGVLVWTMSNPRWTCDYGLAVVPHAVLVLSACGFKPGFPMAEWASKRRAQLDSQV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lprH, lprH and M. tuberculosis,
lipoprotein,
Sanger Rv1418, Tigr MT1461

471 bp forward orf at  [04:20]

-> Mtbook page 492

Function

unknown

Protein

157 aminoacids, 16,9 kDa

>Rv1419 MGELRLVGGVLRVLVVVGAVFDVAVLNAGAASADGPVQLKSRLGDVCLDAPSGSWFSPLVINPCNGTDFQRWNLTDDRQVESVAFPGECVNIGNALWARLQPCVNWISQHWTVQPDGLVKSDLDACLTVLGGPDPGTWVSTRWCDPNAPDQQWDSVP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1419, Tigr MT1462

1938 bp forward orf at  [04:20]

-> Mtbook page 492

uvrC

excinuclease ABC subunit C

Function

Classification II. A.5
Category II. Macromolecule metabolism
Class A. Synthesis and modification of macromolecules
Group 5. DNA replication, repair, recombination and restriction/ modification

Protein

646 aminoacids, 71,6 kDa

>Rv1420 VPDPATYRPAPGSIPVEPGVYRFRDQHGRVIYVGKAKSLRSRLTSYFADVASLAPRTRQLVTTAAKVEWTVVGTEVEALQLEYTWIKEFDPRFNVRYRDDKSYPVLAVTLGEEFPRLMVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSAGVFKRHRQIDRPCLLGYIDKCSAPCIGRVDAAQHRQIVADFCDFLSGKTDRFARALEQQMNAAAEQLDFERAARLRDDLSALKRAMEKQAVVLGDGTDADVVAFADDELEAAVQVFHVRGGRVRGQRGWIVEKPGEPGDSGIQLVEQFLTQFYGDQAALDDAADESANPVPREVLVPCLPSNAEELASWLSGLRGSRVVLRVPRRGDKRALAETVHRNAEDALQQHKLKRASDFNARSAALQSIQDSLGLADAPLRIECVDVSHVQGTDVVGSLVVFEDGLPRKSDYRHFGIREAAGQGRSDDVACIAEVTRRRFLRHLRDQSDPDLLSPERKSRRFAYPPNLYVVDGGAPQVNAASAVIDELGVTDVAVIGLAKRLEEVWVPSEPDPIIMPRNSEGLYLLQRVRDEAHRFAITYHRSKRSTRMTASALDSVPGLGEHRRKALVTHFGSIARLKEATVDEITAVPGIGVATATAVHDALRPDSSGAAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: uvrC, uvrC and M. tuberculosis,
excinuclease ABC subunit C,
Sanger Rv1420, Tigr MT1463

903 bp forward orf at  [04:20]

-> Mtbook page 493

Function

unknown

Protein

301 aminoacids, 32,9 kDa

>Rv1421 MMNHARGVENRSEGGGIDVVLVTGLSGAGRGTAAKVLEDLGWYVADNLPPQLITRMVDFGLAAGSRITQLAVVMDVRSRGFTGDLDSVRNELATRAITPRVVFMEASDDTLVRRYEQNRRSHPLQGEQTLAEGIAAERRMLAPVRATADLIIDTSTLSVGGLRDSIERAFGGDGGATTSVTVESFGFKYGLPMDADMVMDVRFLPNPHWVDELRPLTGQHPAVRDYVLHRPGAAEFLESYHRLLSLVVDGYRREGKRYMTIAIGCTGGKHRSVAIAEALMGLLRSDQQLSVRALHRDLGRE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1421, Tigr MT1464

1026 bp forward orf at  [04:20]

-> Mtbook page 493

Function

unknown

Protein

342 aminoacids, 35,8 kDa

>Rv1422 MTDGIVALGGGHGLYATLSAARRLTPYVTAVVTVADDGGSSGRLRSELDVVPPGDLRMALAALASDSPHGRLWATILQHRFGGSGALAGHPIGNLMLAGLSEVLADPVAALDELGRILGVKGRVLPMCPVALQIEADVSGLEADPRMFRLIRGQVAIATTPGKVRRVRLLPTDPPATRQAVDAIMAADLVVLGPGSWFTSVIPHVLVPGLAAALRATSARRALVLNLVAEPGETAGFSVERHLHVLAQHAPGFTVHDIIIDAERVPSEREREQLRRTATMLQAEVHFADVARPGTPLHDPGKLAAVLDGVCARDVGASEPPVAATQEIPIDGGRPRGDDAWR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1422, Tigr MT1465

975 bp forward orf at  [04:20]

-> Mtbook page 494

putative transcriptional regulator

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

325 aminoacids, 34,9 kDa

>Rv1423 MTTDVKDELSRLVVKSVSARRAEVTSLLRFAGGLHIVGGRVVVEAELDLGSIARRLRKEIFELYGYTAVVHVLSASGIRKSTRYVLRVANDGEALARQTGLLDMRGRPVRGLPAQVVGGSIDDAEAAWRGAFLAHGSLTEPGRSSALEVSCPGPEAALALVGAARRLGVGAKAREVRGADRVVVRDGEAIGALLTRMGAQDTRLVWEERRLRREVRATANRLANFDDANLRRSARAAVAAAARVERALEILGDTVPEHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLLSMADRKAKVDGIPDTESVVTPDLLEDA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative transcriptional regulator,
Sanger Rv1423, Tigr MT1466

759 bp reverse orf at  [04:20]

-> Mtbook page 494

possible membrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

253 aminoacids, 27,4 kDa

>Rv1424c MTVVPGAPSRPASAVSRPSYRQCVQASAQTSARRYSFPSYRRPPAEKLVFPVLLGILTLLLSACQTASASGYNEPRGYDRATLKLVFSMDLGMCLNRFTYDSKLAPSRPQVVACDSREARIRNDGFHANAPSCMRIDYELITQNHRAYYCLKYLVRVGYCYPAVTTPGKPPSVLLYAPSACDESLPSPRVATALVPGTRSANREFSRFVVTEIKSLGAGGRCDSASVSLQPPEEIEGPAIPPASSQLVCVAPK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible membrane protein,
Sanger Rv1424c, Tigr MT1467

1377 bp forward orf at  [04:21]

-> Mtbook page 494

Function

unknown

Protein

459 aminoacids, 50,1 kDa

>Rv1425 MKRLSSVDAAFWSAETAGWHMHVGALAICDPSDAPEYSFQRLRELIIERLPEIPQLRWRVTGAPLGLDRPWFVEDEELDIDFHIRRIGVPAPGGRRELEELVGRLMSYKLDRSRPLWELWVIEGVEGGRIATLTKMHHAIVDGVSGAGLGEILLDITPEPRPPQQETVGFVGFQIPGLERRAIGALINVGIMTPFRIVRLLEQTVRQQIAALGVAGKPARYFEAPKTRFNAPVSPHRRVTGTRVELARAKAVKDAFGVKLNDVVLALVAGAARQYLQKRDELPAKPLIAQIPVSTRSEETKADVGNQVSSMTASLATHIEDPAKRLAAIHESTLSAKEMAKAPSAHQIMGLTETTPPGLLQLAARAYTASGLSHNLAPINLVVSNVPGPPFPLYMAGARLDSLVPLGPPVMDVALNITCFSYQDYLDFGLVTTPEVANDIDEMADAIEPALAELERAAE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1425, Tigr MT1468

1260 bp reverse orf at  [04:21]

-> Mtbook page 495

lipO

probable esterase

Function

Classification II. B.5
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 5. Esterases and lipases

Protein

420 aminoacids, 46,1 kDa

>Rv1426c MRFRRMARPRPLTRAAVELLNAANGLRPLSGSGYSTVLAFWLGWPTSEVPGVYLGASVLDALRRGRRGDFGGLKGKAALALTAAAWVILAVIRYRGATTPGPVLEAGLTEQLGPDYAKELATLPTEPMRSRGRNLPLRTAMARRRYVETTNVVCYGPYGRANLADIWRRRDLPRDAKAPVLVQVPGGAWVLGWRRPQAYPLMSHLAARGWVCVSLNYRVSPRHTWPDHIVDVKRALAWVKENIAAYGGDPNFVAISGGSAGGHLCALAALTPNDPRFQPGFEQVDTSVAAAVPVYGRYDWFTTDAPGRREFVGLLETFVVKRKFSTHRDIFVDASPIHHVRADAPPFFVLHGRHDSLIPVAEAHAFVEELRAVSKSPVAYADLPHAQHAFDVFGSPRAHHTAEAVARFLSWVYATNPPAT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lipO, lipO and M. tuberculosis,
probable esterase,
Sanger Rv1426c, Tigr MT1469

1605 bp reverse orf at  [04:21]

-> Mtbook page 495

fadD12

acyl-CoA synthase

Function

Classification I. A.3
Category I. Small-molecule metabolism
Class A. Degradation
Group 3. Fatty acids

Protein

535 aminoacids, 58,1 kDa

>Rv1427c MRIRQAFGLIATMRRAGLIAPLRPDRYLRIVAAMRREGMGFTAGFAGAARRCPDRPGLIDELGTLTWRQLDERGNALAAALQALPAGPPRVVGIMCRNHRGFVDALLAVNRIGAHILLLNTSFAGPALAEVVTREGVDTVVYDEEFSATVDRALAEKPQATRIVAWTDEDHDLTVEKLVAAHAGRRPEHTGSHGKVILLTSGTTGTPKGARHSGGGIGTLKAILDRTPWRAEEVTVIVAPMFHAWGFSQLVLASSLACTIVTRRRFDPEATLDLIDRHHATGLVVVPVMFDRIMDLPAEIRNRYDGRSLRFAAASGSRMRPDVVIAFMDQFGDVIYNNYNATEAGMIATATPADLRTAPDTAGRPAEGTEIRILDQQFTEVPTGEVGTIYVRNDSQFDGYTSGAAKDFHAGFMSSGDVGYLDENGRLFVVGRDDEMIVSGGENIYPIEVEKTLATHPDVAEAAVIGVDDQQYGQRLAAFVVLKPGVSATPETLKQHVRDNLANYKVPRDIAVLDELPRGITGKILRTELQSRVGS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: fadD12, fadD12 and M. tuberculosis,
acyl-CoA synthase,
Sanger Rv1427c, Tigr MT1470

825 bp reverse orf at  [04:21]

-> Mtbook page 496

Function

unknown

Protein

275 aminoacids, 29,9 kDa

>Rv1428c LSETDSPGNGDDAGIGDIGKFDPGLTQRLISVLRPVLKTYHRSQVHGLDSFPPGGALVVANHSGGMFPMDVPVFSVDFYDKFGYDRPVYTLSHDILFMGLTGDLFRRTGYIRATRENAAKALRSGGVVVVFPGGDYDAYRPTFAENVIDFNGRKGYVSTAVEAGVPIVPAVSIGGQESQLYLSRGTWLARRLGLKRLLRSDILPISFGFPFGFSAAIPPNLPLPAKIVMQVLDPINLTKQFGEDPDVDAVDEHVRSVMQQALNDLAAKRRFPILG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1428c, Tigr MT1471

1266 bp forward orf at  [04:21]

-> Mtbook page 496

Function

unknown

Protein

422 aminoacids, 46,9 kDa

>Rv1429 VAEAGGGPISVIARHMQLIRDDFISELFDKMKAEIRGLDYDARMADLWRASITENFVTAVHYLDRDTPQSLVEAPAAALAYARAAAQRDIPLSGLVRAHRLGHARFLEVAMQYVSLLEPADRVSTIIELVNRSARLVDLVADQLIVAYEHEHDRWLSRRSGLQQQWVSELLADTPVDVPRAERALGYRLDGVHIAAVVWVDSAVPIGDVVAQFDQVRCLLAGELGPELGPVANSLMVPTDEREARLWFSPAPTRAFAPSRIRAAFESAGIRARLACGRVGDGLRGFRASLKQAERVKALALAGGARPGGRVMFYDDVAPVALLADDLEELRRFVTDVLGDLSVDDERNSWLRETLREFLLRNRSYVATADAMILHRNTIQYRVIQAMELCGQNLDDPDAAFRVQMALEVCRWMAPAVLRAKQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1429, Tigr MT1472

1584 bp forward orf at  [04:22]

-> Mtbook page 496

PE

Function

Classification IV. C.1.a
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup a

Protein

528 aminoacids, 54,6 kDa

>Rv1430 MSFVFAVPEMVAATASDLASLGAALSEATAAAAIPTTQVLAAAADEVSAAIAELFGAHGQEFQALSAQASAFHDRFVRALSAAAGWYVDAEAANAALVDTAATGASELGSGGRTALILGSTGTPRPPFDYMQQVYDRYIAPHYLGYAFSGLYTPAQFQPWTGIPSLTYDQSVAEGAGYLHTAIMQQVAAGNDVVVLGFSQGASVATLEMRHLASLPAGVAPSPDQLSFVLLGNPNNPNGGILARFPGLYLQSLGLTFNGATPDTDYATTIYTTQYDGFADFPKYPLNILADVNALLGIYYSHSLYYGLTPEQVASGIVLPVSSPDTNTTYILLPNEDLPLLQPLRGIVPEPLLDLIEPDLRAIIELGYDRTGYADVPTPAALFPVHIDPIAVPPQIGAAIGGPLTALDGLLDTVINDQLNPVVTSGIYQAGAELSVAAAGYGAPAGVTNAIFIGQQVLPILVEGPGALVTADTHYLVDAIQDLAAGDLSGFNQNLQLIPATNIALLVFAAGIPAVAAVAILTGQDFPV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE, PE and M. tuberculosis,
Sanger Rv1430, Tigr MT1474

1767 bp forward orf at  [04:22]

-> Mtbook page 497

possible transporter

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

589 aminoacids, 65,3 kDa

>Rv1431 MGFLKPDLPDVDHDTWLTQPRRTRLQVVTRDWVEHGFGTPYAVYLLYLTKIAVYVAAGAAIISLNPGLGGLSRIGDWWTQPIVYQKVIVFTLLFEVLGFGCGSGPLTGRFWPPIGGFLYWLRPNTIRLPAWPDKVPFTQGDTRTVVDVALYAIVLIGGVWALLSPGSPGPGGTPVTAAGDVGLINPVLVVPTIVALGVLGLRDKTIFLAARGEHYWLKLFVFFFPFTDQIAAFKIIMLCLWWGAATSKLNHHFPYVVAVMTSNNALLRSRVFNPIKHLLYRDHANDLRPSWLPKLMAHGGGTTAEFLVPGILVLVADGHPWRWFLIGFMVLFHLNILSNLPMGVPLEWNVFFIFSLCYLFGHYGAITATDLRSPLLLAIVIAVVAVVIMGNLLPEKISFLPAMRYYAGNWATSIWCFRGDAEATMETSVVKSSALVVNQLAKLYDGATAEIMTDKVAAFRAMHTHGRALNGLLPRALDDEAHYRIREGEIVAGPLVGWNFGEGHLHNEQLVAAVQRRCNFADGDLRVIILEGQPIHVQKQWYRIVDAKTGLFEAGYVTVEDMLSRQPWPEPGDEFPVHVTTQRGTPSKP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible transporter,
Sanger Rv1431, Tigr MT1475

1419 bp forward orf at  [04:22]

-> Mtbook page 497

putative dehydrogenase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

473 aminoacids, 50,5 kDa

>Rv1432 MTTAVVVGAGPNGLAAAIHLARHGVDVQVLEARDTIGGGARSGELTVPGVIHDHCSAFHPLGVGSPFWAAIDLQRYGLTWKWPDVDCAHPLDDGTAGVLYRSIEATAAGLGPDGKRWQRAVGDLAAGFDELAEDLLRPVLNMPRHPIRLARFGPRAALPATAMARRFHTERARALFGGAAAHVYTRLDRPLTASLGLMILASGHRHGWPVARGGSGSITKALAAALDAYGGTVATGVTVTSRRDIPDADIVMLDLSPAAVLGIYGDVMPTRINRSYRRYRAGSSAFKVDFAIEGDVGWTNPDCRRAGTVHLGGTFAEIADTERQRAQGTMVQRPFVLVGQQYLADPSRSVGNINPIWAYAHVPFGYTGDATAAVIDQIERFAPGFRDRIVATVSTSTTELQTYNRNFIGGDIIGGANDRLQVIFRPRVAVDPYAIGVPGVYLCSQSAPPGAGIHGLCGYHAAESALRWLRKRR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative dehydrogenase,
Sanger Rv1432, Tigr MT1476

813 bp forward orf at  [04:22]

-> Mtbook page 498

possible membrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

271 aminoacids, 28,7 kDa

>Rv1433 MRAVFGCAIAVVGIAGSVVAGPADIHLVAAKQSYGFAVASVLPTRGQVVGVAHPVVVTFSAPITNPANRHAAERAVEVKSTPAMTGKFEWLDNDVVQWVPDRFWPAHSTVELSVGSLSSDFKTGPAVVGVASISQHTFTVSIDGVEEGPPPPLPAPHHRVHFGEDGVMPASMGRPEYPTPVGSYTVLSKERSVIMDSSSVGIPVDDPDGYRLSVDYAVRITSRGLYVHSAPWALPALGLENVSHGCISLSREDAEWYYNAVDIGDPVIVQE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible membrane protein,
Sanger Rv1433, Tigr MT1477

135 bp forward orf at  [04:23]

-> Mtbook page 498

Function

unknown

Protein

45 aminoacids, 4,6 kDa

>Rv1434 MRASPAERVDGAYAGAGPHTQSVLEEDQRQRAPAGAEAEGPGRTG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1434, Tigr MT1478

606 bp reverse orf at  [04:23]

-> Mtbook page 498

Function

unknown

Protein

202 aminoacids, 18,5 kDa

>Rv1435c LTLMAIVNRFNIKVIAGAGLFAAAIALSPDAAADPLMTGGYACIQGMAGDAPVAAGDPVAAGGPAAAGACSAALTDMAGVPFVAPGPVPAAAPVPIGAPVPIPGAPVPIPGAPVPIPGGPVPIPGAPVPVPAVPAPVIPVGTPLIALGPVLAGAPGDGVVSAPIIGMSGVKDALTDPAPAGGPVPGQPVLPGPSASAPAGAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1435c, Tigr MT1479

1017 bp forward orf at  [04:23]

-> Mtbook page 498

gap

glyceraldehyde 3-phosphate dehydrogenase

Function

Classification I. B.1
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 1. Glycolysis

Protein

339 aminoacids, 35,9 kDa

>Rv1436 VTVRVGINGFGRIGRNFYRALLAQQEQGTADVEVVAANDITDNSTLAHLLKFDSILGRLPCDVGLEGDDTIVVGRAKIKALAVREGPAALPWGDLGVDVVVESTGLFTNAAKAKGHLDAGAKKVIISAPATDEDITIVLGVNDDKYDGSQNIISNASCTTNCLAPLAKVLDDEFGIVKGLMTTIHAYTQDQNLQDGPHKDLRRARAAALNIVPTSTGAAKAIGLVMPQLKGKLDGYALRVPIPTGSVTDLTVDLSTRASVDEINAAFKAAAEGRLKGILKYYDAPIVSSDIVTDPHSSIFDSGLTKVIDDQAKVVSWYDNEWGYSNRLVDLVTLVGKSL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: gap, gap and M. tuberculosis,
glyceraldehyde 3-phosphate dehydrogenase,
Sanger Rv1436, Tigr MT1480

1236 bp forward orf at  [04:23]

-> Mtbook page 499

pgk

phosphoglycerate kinase

Function

Classification I. B.1
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 1. Glycolysis

Protein

412 aminoacids, 42,5 kDa

>Rv1437 MSVANLKDLLAEGVSGRGVLVRSDLNVPLDEDGTITDAGRIIASAPTLKALLDADAKVVVAAHLGRPKDGPDPTLSLAPVAVALGEQLGRHVQLAGDVVGADALARAEGLTGGDILLLENIRFDKRETSKNDDDRRALAKQLVELVGTGGVFVSDGFGVVHRKQASVYDIATLLPHYAGTLVADEMRVLEQLTSSTQRPYAVVLGGSKVSDKLGVIESLATKADSIVIGGGMCFTFLAAQGFSVGTSLLEDDMIEVCRGLLETYHDVLRLPVDLVVTEKFAADSPPQTVDVGAVPNGLMGLDIGPGSIKRFSTLLSNAGTIFWNGPMGVFEFPAYAAGTRGVAEAIVAATGKGAFSVVGGGDSAAAVRAMNIPEGAFSHISTGGGASLEYLEGKTLPGIEVLSREQPTGGVL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pgk, pgk and M. tuberculosis,
phosphoglycerate kinase,
Sanger Rv1437, Tigr MT1481

783 bp forward orf at  [04:23]

-> Mtbook page 499

tpi

triosephosphate isomerase

Function

Classification I. B.1
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 1. Glycolysis

Protein

261 aminoacids, 27,4 kDa

>Rv1438 VSRKPLIAGNWKMNLNHYEAIALVQKIAFSLPDKYYDRVDVAVIPPFTDLRSVQTLVDGDKLRLTYGAQDLSPHDSGAYTGDVSGAFLAKLGCSYVVVGHSERRTYHNEDDALVAAKAATALKHGLTPIVCIGEHLDVREAGNHVAHNIEQLRGSLAGLLAEQIGSVVIAYEPVWAIGTGRVASAADAQEVCAAIRKELASLASPRIADTVRVLYGGSVNAKNVGDIVAQDDVDGGLVGGASLDGEHFATLAAIAAGGPLP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: tpi, tpi and M. tuberculosis,
triosephosphate isomerase,
Sanger Rv1438, Tigr MT1483

423 bp reverse orf at  [04:23]

-> Mtbook page 500

Function

unknown

Protein

141 aminoacids, 16 kDa

>Rv1439c MQMSASNAFVEGFADFWKAPSPDRLTDHLHPDVVLVRPLSPPRHGLGAAQREFTRILGLLPDLHGEVDRWSQAGDVVFIEFRLIARLGSEVVEWPVVDRFLLRGDKAVERVSYFDSLPLLIKVVKHPSAWRGWLTTMRSRA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1439c, Tigr MT1484

351 bp forward orf at  [04:24]

-> Mtbook page 500

secG

protein-export membrane protein SecG

Function

Classification III. D
Category III. Cell processes
Class D. Protein and peptide secretion

Protein

117 aminoacids, 12,1 kDa

>Rv1440 VAGVTAAVSARLKADEARRPGFYAAGSGPLPQVRGSTLPVMELALQITLIVTSVLVVLLVLLHRAKGGGLSTLFGGGVQSSLSGSTVVEKNLDRLTLFVTGIWLVSIIGVALLIKYR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: secG, secG and M. tuberculosis,
protein-export membrane protein SecG,
Sanger Rv1440, Tigr MT1485

1473 bp reverse orf at  [04:24]

-> Mtbook page 500

PE_PGRS

Function

Classification IV. C.1.b
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup b

Protein

491 aminoacids, 40,8 kDa

>Rv1441c MSNVMVVPGMLSAAAADVASIGAALSAANGAAAPTTAGVLAAGADEVSAAIASLFSGYARDYQALSAQMARFHQQFVQALTASVGSYAAAEAANASPLQALEQQVLAAINAPTQTLLGRPLIGNGADGLPGQNGGAGGLLWGNGGNGGAGDAAHPNGGNGGDAGMFGNGGAGGAGYSPAAGTGAAGGAGGAGGAGGWLSGNGGAGGNGGTGASGADGGGGLPPVPASPGGNGGGGDAGGAAGMFGTGGAGGTGGDGGAGGAGDSPNSGANGARGGDGGNGAAGGAGGRLFGNGGAGGNGGTAGQGGDGGTALGAGGIGGDGGTGGAGGTGGTAGIGGSSAGAGGAGGDGGAGGTGGGSSMIGGKGGTGGNGGVGGTGGASALTIGNGSSAGAGGAGGAGGTGGTGGYIESLDGKGQAGNGGNGGNGAAGGAGGGGTGAGGNGGAGGNGGDGGPSQGGGNPGFGGDGGTGGPGGVGVPDGIGGANGAQGKHG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE_PGRS, PE_PGRS and M. tuberculosis,
Sanger Rv1441c, Tigr MT1486

2298 bp forward orf at  [04:24]

-> Mtbook page 500

bisC

biotin sulfoxide reductase

Function

Classification I. G.1
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 1. Biotin

Protein

766 aminoacids, 83,4 kDa

>Rv1442 MQVYTSATHWGVFTARVHGGDIAAVAALASDTNPAPQLQNLPGAVRHRSRIANPAVRRGWLQHGPGPSSARGAEEFVEVSWDELIELLASELRRTVDRYGNEAIYGSSYGWASAGRFHHAQSQVHRFLNMLGGYTASRHSYSAGASEVIFPHIVGAALFEALAETTTWDVIVDHTALLVAFGGLPVKNTAVMPGGTTAHPDRDYVGRYRARGGRLVSVSPLRDDIAAIAGPLDDRCRWLAPVPGTDVAIMLGLAYVLATESLADRAFLGRYCTGYERFERYLLGLDDGIPKTPEWAAALSGLAAGDLRDLARRMAEHRTLITTSLSLQRIEHGEQTVWMAATLAAMLGQIGLPGGGFGHGYSSNGVGNPPLACGLPALPQGNNPVSTFIPVAAISELLQRPGQRLAYNGRLLELPDIKCVYWAGGNPFHHHQNLPRLRRALSRVDTIVVHEQYWTAMAKHADIVVPTTTSFERDDFAASKTNPTLIAMPAMVPPYANARDDYHTFSALAHRLGFGKQFTEGRSAREWLEHMYDKWSAELDFPVPSFAEFWRTGRLELPTRTGLTWLADFRADPAAHPLGTPSGRIEIFSDTVDAFALPDCAGHPTWYEPSEWLGGPRAARYPLHLIANQPRTRLHSQLDHGGASMASKIRGREPIRIHPDDAAARELTDGDIVRVFNDRGACLAGVVIDDGLRPKVVQLSTGAWFDPADPRDPDSMCVHGNPNALSNDSGTSSLAHGSTGQHVLVQIERFTGELPPVRAHEPPRLA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: bisC, bisC and M. tuberculosis,
biotin sulfoxide reductase,
Sanger Rv1442, Tigr MT1487