1737 bp forward orf at  [03:47]

-> Mtbook page 431

probable drug efflux protein

Function

Classification III. A.6
Category III. Cell processes
Class A. Transport/binding proteins
Group 6. Efflux proteins

Protein

579 aminoacids, 60,9 kDa

>Rv1250 MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable drug efflux protein,
Sanger Rv1250, Tigr MT1289

3417 bp reverse orf at  [03:47]

-> Mtbook page 431

Function

unknown

Protein

1139 aminoacids, 123,1 kDa

>Rv1251c VFVTGDSIVYSASDLAAAARCQYALLREFDAKLGRGPAVAVDDELMARAAVLGSAHEGRRLDQLRHEFGDAVAIIGRPAYTPAGLAAAADATRRAIANHAPVVYQAAMFDGRFVGFADFLIRDGHRYRVADTKLARSPTVTALLQLAAYADALVHSGVPVAADAELELGDGTIVRYRVGELIPVYRSQRALLQRLLDGHYTAGTAVRWDDERVQACFRCPQCTERLRASDDLLLVGGMRVRQRDKLLEAGITTIAELADHTAPVPGLTTNALGKLTAQAKLQIRQRDTGAPQFEIVDPRPLTLLPEPNPGDLFFDFEGDPLWTADGKQWGLEYLFGVLEAGRAGVFRPLWAHDRTAERQALTDFLAIVARRRRRHPNMHIYHYAPYEKTALLRLVGRYGIGEDDVDDLLRNGVLVDLYPLVRKSIRVGTDSFSLKALEPLYLGTQPRSGDVTTAADSINSYARYCELRAAGRIDEAATVLKEIEGYNHYDCRSTRALRDWLLMRAWEAGVTPIGAQPVPDADPIDDGDSLASVLSKFTGDAAAGERTPEQTAVALLAAARGYHRREDKPFWWAHFDRLNYPVDEWSDSTDVFLASEASVTVDWHMPPRARKPQRRVRLTGELARGDLNGNVFALYEPPAPPGMTDNPDRRAAGPAAVVETDDPTVPTEVVIVERTGSDGNTFQQLPFALAPGPPVPTTALRESIESTAAAVASGSPQLPSTALMDVLLRRPPRTRSGAALPRSSDPVTDIAAAALDLDSSYLAVHGPPGTGKTYTAARVIAELVTEHAWRIGVVAQSHATVENLLEGVISAGLDPGQVAKKPHDHTAGRWQSIDGSQYTEFIRDTAGCVIGGTAWDFANGNRVPKASLDLLVIDEAGQFCLANTIAVAPAATNLLLLGDPQQLPQVSQGTHPEPVDTSALSWLVDGQHTLPDERGYFLDRSYRMHPAVCAAVSALSYEGRLCSHTERTAVRRLDGYPPGVHTRGVHHKGNSIESPEEAEAILAELRQLLGSPWTDEHGTRPLAASDVLVLAPYNAQVALVRRRLASAGLGGADGVRVGTVDKFQGGQAPVVFISMTASSADDVPRGISFLLNRNRLNVAVSRAQYAAVIVRSELLTQYLPATPDGLVDLGAFLGLTSTS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1251c, Tigr MT1290

606 bp reverse orf at  [03:48]

-> Mtbook page 432

lprE

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

202 aminoacids, 20,4 kDa

>Rv1252c VPGVWSPPCPTTPRVGVVAALVAATLTGCGSGDSTVAKTPEATPSLSTAHPAPPSSEPSPPSATAAPPSNHSAAPVDPCAVNLASPTIAKVVSELPRDPRSEQPWNPEPLAGNYNECAQLSAVVIKANTNAGNPTTRAVMFHLGKYIPQGVPDTYGFTGIDTSQCTGDTVALTYASGIGLNNVVKFRWNGGGVELIGNTTGG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lprE, lprE and M. tuberculosis,
lipoprotein,
Sanger Rv1252c, Tigr MT1291

1689 bp forward orf at  [03:48]

-> Mtbook page 433

deaD

ATP-dependent DNA/RNA helicase

Function

Classification II. A.7
Category II. Macromolecule metabolism
Class A. Synthesis and modification of macromolecules
Group 7. RNA synthesis, RNA modification and DNA transcription

Protein

563 aminoacids, 61,5 kDa

>Rv1253 MAFPEYSPAASAATFADLQIHPRVLRAIGDVGYESPTAIQAATIPALMAGSDVVGLAQTGTGKTAAFAIPMLSKIDITSKVPQALVLVPTRELALQVAEAFGRYGAYLSQLNVLPIYGGSSYAVQLAGLRRGAQVVVGTPGRMIDHLERATLDLSRVDFLVLDEADEMLTMGFADDVERILSETPEYKQVALFSATMPPAIRKLSAKYLHDPFEVTCKAKTAVAENISQSYIQVARKMDALTRVLEVEPFEAMIVFVRTKQATEEIAEKLRARGFSAAAISGDVPQAQRERTITALRDGDIDILVATDVAARGLDVERISHVLNYDIPHDTESYVHRIGRTGRAGRSGAALIFVSPRELHLLKAIEKATRQTLTEAQLPTVEDVNTQRVAKFADSITNALGGPGIELFRRLVEEYEREHDVPMADIAAALAVQCRGGEAFLMAPDPPLSRRNRDQRRDRPQRPKRRPDLTTYRVAVGKRHKIGPGAIVGAIANEGGLHRSDFGQIRIGPDFSLVELPAKLPRATLKKLAQTRISGVLIDLRPYRPPDAARRHNGGKPRRKHVG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: deaD, deaD and M. tuberculosis,
ATP-dependent DNA/RNA helicase,
Sanger Rv1253, Tigr MT1292

1149 bp forward orf at  [03:48]

-> Mtbook page 433

acyltransferase

Function

Classification IV. H
Category IV. Other
Class H. Miscellaneous transferases (61)

Protein

383 aminoacids, 42,3 kDa

>Rv1254 MTLPKERAAQGGLERIAHVDRVASLTGIRAVAALLVVGTHAAYTTGKYTHGYWGLMSSRMEIGVPIFFVLSGFLLFRPWVKSAATGGPPPSLSRYAWHRVRRIMPAYTVTVLLAYLVYHFRTAGPNPGHTWVGLFRNLTLTQIYTDGYLGAFLHQGLTQMWSLAVEVAFYLALPALAYLLLVLVCRRRWQPRLLLATMAGLTMISPAWLILVHNTHWMPDGARLWLPTYLAWFVGGMMLAVLAAMGVRCYAFVAIPLAVICYFIVSTPIAGAPTTSPTALAEALVKTAFYAVIAVLAVAPLALGDQGWYAQLLASRPMVFLGEISYEIFLIHLVTMEIAMVDVLGYRVYTSSMVNLCLVTLVLTIPLAWLLHRFTRVQGDRPS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

acyltransferase,
Sanger Rv1254, Tigr MT1293

606 bp reverse orf at  [03:48]

-> Mtbook page 433

transcriptional regulator (TetR/AcrR family)

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

202 aminoacids, 22,2 kDa

>Rv1255c MAGTDWLSARRTELAADRILDAAERLFTQRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAEFVVPIVTPASAAARKAGHPGPE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

transcriptional regulator (TetR/AcrR family),
Sanger Rv1255c, Tigr MT1294

1215 bp reverse orf at  [03:49]

-> Mtbook page 434

Probable cytochrome P-450

Function

Classification IV. F
Category IV. Other
Class F. Cytochrome P450 enzymes (22)

Protein

405 aminoacids, 44,6 kDa

>Rv1256c MTSVMSHEFQLATAETWPNPWPMYRALRDHDPVHHVVPPQRPEYDYYVLSRHADVWSAARDHQTFSSAQGLTVNYGELEMIGLHDTPPMVMQDPPVHTEFRKLVSRGFTPRQVETVEPTVRKFVVERLEKLRANGGGDIVTELFKPLPSMVVAHYLGVPEEDWTQFDGWTQAIVAANAVDGATTGALDAVGSMMAYFTGLIERRRTEPADDAISHLVAAGVGADGDTAGTLSILAFTFTMVTGGNDTVTGMLGGSMPLLHRRPDQRRLLLDDPEGIPDAVEELLRLTSPVQGLARTTTRDVTIGDTTIPAGRRVLLLYGSANRDERQYGPDAAELDVTRCPRNILTFSHGAHHCLGAAAARMQCRVALTELLARCPDFEVAESRIVWSGGSYVRRPLSVPFRVTS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Probable cytochrome P-450,
Sanger Rv1256c, Tigr MT1295

1365 bp reverse orf at  [03:49]

-> Mtbook page 434

similar to many dehydrogenases

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

455 aminoacids, 47,2 kDa

>Rv1257c VNTDVLAGLMAELPEGMVVTDPAVTDGYRQDRAFDPSAGKPLAIIRPRRTEEVQTVLRWASANQVPVVTRGAGSGLSGGATALDGGIVLSTEKMRDITVDPVTRTAVCQPGLYNAEVKEAAAEHGLWYPPDPSSFEICSIGGNIATNAGGLCCVKYGVTGDYVLGMQVVLANGTAVRLGGPRLKDVAGLSLTKLFVGSEGTLGVITEVTLRLLPAQNASSIVVASFGSVQAAVDAVLGVTGRLRPAMLEFMDSVAINAVEDTLRMDLDRDAAAMLVAGSDERGRAATEDAAVMAAVFAENGAIDVFSTDDPDEGEAFIAARRFAIPAVESKGALLLEDVGVPLPALGELVTGIARIAEERNLMISVIAHAGDGNTHPLLVYDPADAAMLERAHLAYGEIMDLAVGLGGTITGEHGVGRLKRPWLAGYLGPDVLALNQRIKQALDPQGILNPGSAI*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

similar to many dehydrogenases,
Sanger Rv1257c, Tigr MT1296

1257 bp reverse orf at  [03:49]

-> Mtbook page 434

probable multidrug resistance pump

Function

Classification III. A.6
Category III. Cell processes
Class A. Transport/binding proteins
Group 6. Efflux proteins

Protein

419 aminoacids, 43,3 kDa

>Rv1258c MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGSAGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLDRINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQADIDRPVGSAQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable multidrug resistance pump,
Sanger Rv1258c, Tigr MT1297

897 bp forward orf at  [03:49]

-> Mtbook page 435

Function

unknown

Protein

299 aminoacids, 31,8 kDa

>Rv1259 MNIAAESSAKPVWGPPNFCAAAARMQDVRVLMHPKTGRAFRSPVEPGSGWPGDPATPQTPVAADAAQVSALAGGAGSICELNALISVCRACPRLVSWREEVAVVKRRAFADQPYWGRPVPGWGSKRPRLLILGLAPAAHGANRTGRMFTGDRSGDQLYAALHRAGLVNSPVSVDAADGLRANRIRITAPVRCAPPGNSPTPAERLTCSPWLNAEWRLVSDHIRAIVALGGFAWQVALRLAGASGTPKPRFGHGVVTELGAGVRLLGCYHPSQQNMFTGRLTPTMLDDIFREAKKLAGIE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1259

1116 bp forward orf at  [03:49]

-> Mtbook page 435

probable oxidoreductase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

372 aminoacids, 41,3 kDa

>Rv1260 VKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAIDVRGPALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTESTPTGGPVNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQDDGDSVRVTFERAAAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHAAIFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRIDYRDTEAQFAELQRRMAEDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSRGRVALVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAGDDYQLGFANYHAEFHGFVERNQWLVSDNIPGGAPIPQEEFERIVHSITIKDY*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable oxidoreductase,
Sanger Rv1260, Tigr MT1298

447 bp reverse orf at  [03:50]

-> Mtbook page 436

Function

unknown

Protein

149 aminoacids, 16,8 kDa

>Rv1261c MDISRWLERHVGVQLLRLHDAIYRGTNGRIGHRIPGAPPSLLLHTTGAKTSQPRTTSLTYARDGDAYLIVASKGGDPRSPGWYHNLKANPDVEINVGPKRFGVTAKPVQPHDPDYARLWQIVNENNANRYTNYQSRTSRPIPVVVLTRR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1261c, Tigr MT1299

432 bp reverse orf at  [03:50]

-> Mtbook page 436

Function

unknown

Protein

144 aminoacids, 15,7 kDa

>Rv1262c MPCVFCAIIAGEAPAIRIYEDGGYLAILDIRPFTRGHTLVLPKRHTVDLTDTPPEALADMVAIGQRIARAARATKLADATHIAINDGRAAFQTVFHVHLHVLPPRNGDKLSVAKGMMLRRDPDREATGRILREALAQQDAAAQD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1262c, Tigr MT1300

1386 bp forward orf at  [03:50]

-> Mtbook page 436

amiB2

putative amidase AMI2_MYCTU Q11056

Function

Classification IV. I
Category IV. Other
Class I. Miscellaneous phosphatases, lyases, and hydrolases (18)

Protein

462 aminoacids, 49,1 kDa

>Rv1263 VDPTDLAFAGAAAQARMLADGALTAPMLLEVYLQRIERLDSHLRAYRVVQFDRARAEAEAAQQRLDAGERLPLLGVPIAIKDDVDIAGEVTTYGSAGHGPAATSDAEVVRRLRAAGAVIIGKTNVPELMIMPFTESLAFGATRNPWCLNRTPGGSSGGSAAAVAAGLAPVALGSDGGGSIRIPCTWCGLFGLKPQRDRISLEPHDGAWQGLSVNGPIARSVMDAALLLDATTTVPGPEGEFVAAAARQPGRLRIALSTRVPTPLPVRCGKQELAAVHQAGALLRDLGHDVVVRDPDYPASTYANYLPRFFRGISDDADAQAHPDRLEARTRAIARLGSFFSDRRMAALRAAEVVLSSRIQSIFDDVDVVVTPGAATGPSRIGAYQRRGAVSTLLLVVQRVPYFQVWNLTGQPAAVVPWDFDGDGLPMSVQLVGRPYDEATLLALAAQIESARPWAHRRPSVS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: amiB2, amiB2 and M. tuberculosis,
putative amidase AMI2_MYCTU Q11056,
Sanger Rv1263, Tigr MT1301

1191 bp forward orf at  [03:50]

-> Mtbook page 436

similar to adenylate cyclases

Function

Classification IV. J
Category IV. Other
Class J. Cyclases (6)

Protein

397 aminoacids, 42,2 kDa

>Rv1264 VTDHVREADDANIDDLLGDLGGTARAERAKLVEWLLEQGITPDEIRATNPPLLLATRHLVGDDGTYVSAREISENYGVDLELLQRVQRAVGLARVDDPDAVVHMRADGEAAARAQRFVELGLNPDQVVLVVRVLAEGLSHAAEAMRYTALEAIMRPGATELDIAKGSQALVSQIVPLLGPMIQDMLFMQLRHMMETEAVNAGERAAGKPLPGARQVTVAFADLVGFTQLGEVVSAEELGHLAGRLAGLARDLTAPPVWFIKTIGDAVMLVCPDPAPLLDTVLKLVEVVDTDNNFPRLRAGVASGMAVSRAGDWFGSPVNVASRVTGVARPGAVLVADSVREALGDAPEADGFQWSFAGPRRLRGIRGDVRLFRVRRGATRTGSGGAAQDDDLAGSSP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

similar to adenylate cyclases,
Sanger Rv1264, Tigr MT1302

678 bp forward orf at  [03:50]

-> Mtbook page 437

Function

unknown

Protein

226 aminoacids, 25,2 kDa

>Rv1265 MVLARPDAVFAPARNRCHVSLPVNAMSLKMKVCNHVIMRHHHMHGRRYGRPGGWQQAQQPDASGAAEWFAGRLPEDWFDGDPTVIVDREEITVIGKLPGLESPEEESAARASGRVSRFRDETRPERMTIADEAQNRYGRKVSWGVEVGGERILFTHIAVPVMTRLKQPERQVLDTLVDAGVARSRSDALAWSVKLVGEHTEEWLAKLRTAMSAVDDLRAQGPDLPA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1265, Tigr MT1303

1878 bp reverse orf at  [03:50]

-> Mtbook page 437

pknH

serine-threonine protein kinase

Function

Classification I. J.3
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 3. Serine-threonine protein kinases and phosphoprotein phosphatases

Protein

626 aminoacids, 66,8 kDa

>Rv1266c MSDAQDSRVGSMFGPYHLKRLLGRGGMGEVYEAEHTVKEWTVAVKLMTAEFSKDPVFRERMKREARIAGRLQEPHVVPIHDYGEVDGQMFLEMRLVEGTDLDSVLKRFGPLTPPRAVAIITQIASALDAAHADGVMHRDVKPQNILITRDDFAYLVDFGIASATTDEKLTQLGTAVGTWKYMAPERFSNDEVTYRADIYALACVLHECLTGAPPYRADSAGTLVSSHLMGPIPQPSAIRPGIPKAFDAVVARGMAKKPEDRYASAGDLALAAHEALSDPDQDHAADILRRSQESTLPAPPKPVPPPTMPATAMAPRQPPAPPVTPPGVQPAPKPSYTPPAQPGPAGQRPGPTGQPSWAPNSGPMPASGPTPTPQYYQGGGWGAPPSGGPSPWAQTPRKTNPWPLVAGAAAVVLVLVLGAIGIWIAIRPKPVQPPQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYRITNQAGQIAAKIVDKVNKE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pknH, pknH and M. tuberculosis,
serine-threonine protein kinase,
Sanger Rv1266c, Tigr MT1304

1164 bp reverse orf at  [03:51]

-> Mtbook page 438

embR

regulator of embABgenes (AfsR/DndI/RedD family)

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

388 aminoacids, 41,9 kDa

>Rv1267c MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAGIDPRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATRIGRLHDNDIVLDSANVSRHHAVIVDTGTNYVINDLRSSNGVHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: embR, embR and M. tuberculosis,
regulator of embABgenes (AfsR/DndI/RedD family),
Sanger Rv1267c, Tigr MT1305

696 bp reverse orf at  [03:51]

-> Mtbook page 438

Function

unknown

Protein

232 aminoacids, 24 kDa

>Rv1268c MTTSKIATAFKTATFALAAGAVALGLASPADAAAGTMYGDPAAAAKYWRQQTYDDCVLMSAADVIGQVTGREPSERAIIKVAQSTPSVVHPGSIYTKPADAEHPNSGMGTSVADIPTLLAHYGVDAVITDEDHATATGVATGMAALEQYLGSGHAVIVSINAEMIWGQPVEETDSAGNPRSDHAVVVTGVDTENGIVHLNDSGTPTGRDEQIPMETFVEAWATSHDFMAVTT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1268c, Tigr MT1306

372 bp reverse orf at  [03:51]

-> Mtbook page 438

Function

unknown

Protein

124 aminoacids, 12,6 kDa

>Rv1269c MTTMITLRRRFAVAVAGVATAAATTVTLAPAPANAADVYGAIAYSGNGSWGRSWDYPTRAAAEATAVKSCGYSDCKVLTSFTACGAVAANDRAYQGGVGPTLAAAMKDALTKLGGGYIDTWACN*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1269c, Tigr MT1307

732 bp reverse orf at  [03:51]

-> Mtbook page 438

lprA

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

244 aminoacids, 24,9 kDa

>Rv1270c MKHPPCSVVAAATAILAVVLAIGGCSTEGDAGKASDTAATASNGDAAMLLKQATDAMRKVTGMHVRLAVTGDVPNLRVTKLEGDISNTPQTVATGSATLLVGNKSEDAKFVYVDGHLYSDLGQPGTYTDFGNGASIYNVSVLLDPNKGLANLLANLKDASVAGSQQADGVATTKITGNSSADDIATLAGSRLTSEDVKTVPTTVWIASDGSSHLVQIQIAPTKDTSVTLTMSDWGKQVTATKPV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lprA, lprA and M. tuberculosis,
lipoprotein,
Sanger Rv1270c, Tigr MT1308

339 bp reverse orf at  [03:51]

-> Mtbook page 439

Function

unknown

Protein

113 aminoacids, 11,6 kDa

>Rv1271c MLSPLSPRIIAAFTTAVGAAAIGLAVATAGTAGANTKDEAFIAQMESIGVTFSSPQVATQQAQLVCKKLASGETGTEIAEEVLSQTNLTTKQAAYFVVDATKAYCPQYASQLT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1271c, Tigr MT1309

1893 bp reverse orf at  [03:51]

-> Mtbook page 439

probable ABC transporter

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

631 aminoacids, 68,3 kDa

>Rv1272c VTAPPGARPRAASPPPNMRSRDFWGSAARLVKRLAPQRRLSIAVITLGIAGTTIGVIVPRILGHATDLLFNGVIGRGLPGGITKAQAVASARARGDNTFADLLSGMNVVPGQGVDFAAVERTLALALALYLAAALMIWAQARLLNLTVQKTMVRLRTDVEDKVHRLPLSYFDGQQRGELLSRVTNDIDNLQSSLSMTISQLVTSILTMVAVLAMMVSISGLLALITLLTVPLSLLVTRAITRRSQPLFVAHWTSTGRLNAHLEETYSGFTVVKTFGHQAAARERFHELNDDVYQAGFGAQFLSGLVQPATAFIGNLGYVAVAVAGGLQVATGQITLGSIQAFIQYIRQFNMPLSQLAGMYNALQSGVASAERVFDVLDEPEESPEPEPELPNLTGRVEFEHVNFAYLPGTPVIRDLSLVAEPGSTVAIVGPTGAGKTTLVNLLMRFYEIGSGRILIDGVDIASVSRQSLRSRIGMVLQDTWLYDGTIAENIAYGRPEATTDEIVEAARAAHVDRFVNTLPAGYQTRVSGDGGSISVGEKQLITIARAFLARPQLLILDEATSSVDTRTELLIQRAMRELRRDRTSFIIAHRLSTIRDADHILVVQTGQIVERGNHAELLARRGVYYQMTRA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable ABC transporter,
Sanger Rv1272c, Tigr MT1310

1746 bp reverse orf at  [03:52]

-> Mtbook page 439

ABC transporter

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

582 aminoacids, 62,1 kDa

>Rv1273c MLLALLRQHIRPYRRLVAMLMMLQLVSTLASLYLPTVNAAIVDDGVAKGDTATIVRLGAVMLGVTGLQVLCAIGAVYLGSRTGAGFGRDLRSAMFEHIITFSERETARFGAPTLLTRSTNDVRQILFLVQMTATVLVTAPIMCVGGIIMAIHQEAALTWLLLVSVPILAVANYWIISHMLPLFRRMQSLIDGINRVMRDQLSGVRVVRAFTREGYERDKFAQANTALSNAALSAGNWQALMLPVTTLTINASSVALIWFGGLRIDSGQMQVGSLIAFLSYFAQILMAVLMATMTLAVLPRASVCAERITEVLSTPAALGNPDNPKFPTDGVTGVVRLAGATFTYPGADCPVLQDISLTARPGTTTAIVGSTGSGKSTLVSLICRLYDVTAGAVLVDGIDVREYHTERLWSAIGLVPQRSYLFSGTVADNLRYGGGPDQVVTEQEMWEALRVAAADGFVQTDGLQTRVAQGGVNFSGGQRQRLAIARAVIRRPAIYVFDDAFSALDVHTDAKVHASLRQVSGDATIIVVTQRISNAAQADQVIVVDNGKIVGTGTHETLLADCPTYAEFAASQSLSATVGGVG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

ABC transporter,
Sanger Rv1273c, Tigr MT1311

555 bp forward orf at  [03:52]

-> Mtbook page 440

lprB

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

185 aminoacids, 19,7 kDa

>Rv1274 VRRKVRRLTLAVSALVALFPAVAGCSDSGDNKPGATIPSTPANAEGRHGPFFPQCGGVSDQTVTELTRVTGLVNTAKNSVGCQWLAGGGILGPHFSFSWYRGSPIGRERKTEELSRASVEDINIDGHSGFIAIGNEPSLGDSLCEVGIQFSDDFIEWSVSFSQKPFPLPCDIAKELTRQSIANSK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lprB, lprB and M. tuberculosis,
lipoprotein,
Sanger Rv1274, Tigr MT1312

540 bp forward orf at  [03:52]

-> Mtbook page 440

lprC

lipoprotein

Function

Classification II. C.1
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 1. Lipoproteins ( lppA-lpr0)65

Protein

180 aminoacids, 18,9 kDa

>Rv1275 MRRVLVGAAALITALLVLTGCTKSISGTAVKAGGAGVPRNNNSQERYPNLLKECEVLTTDILAKTVGADPLDIQSTFVGAICRWQAANPAGLIDITRFWFEQGSLSNERKVAEGLKYQVETRAIQGVDSIVMRTGDPNGACGVASDAAGVVGWWVNPQAPGIDACGQAIKLMELTLATNA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lprC, lprC and M. tuberculosis,
lipoprotein,
Sanger Rv1275

474 bp reverse orf at  [03:52]

-> Mtbook page 440

Function

unknown

Protein

158 aminoacids, 16,5 kDa

>Rv1276c MRHAKSAYPDGIADHDRPLAPRGIREAGLAGGWLRANLPAVDAVLCSTATRARQTLAHTGIDAPARYAERLYGAAPGTVIEEINRVGDNVTTLLVVGHEPTTSALAIVLASISGTDAAVAERISEKFPTSGIAVLRVAGHWADVEPGCAALVGFHVPR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1276c, Tigr MT1313