687 bp forward orf at  [03:20]

-> Mtbook page 381

probable esterase pseudogene

Function

Classification II. B.5
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 5. Esterases and lipases

Protein

229 aminoacids, 25,2 kDa

>Rv1104 MVVDSCVAESRYGPVRGADDGRVKVWKGIRYAAPPLGDLRFRTPEPPERWTEVADATTFGPACPQPAIPNMPLDLGASQSEDCWSLNIWAPADTEPGDGKPVMVWLHGGAYILGSGSQPLYNGRRLAASGDVVVVTVNYRLGALGFLDLSSFNTSRRRFDSNIGLRDVLAVLRWVADNIAVFGGDPEKVTLFGESARESSRPCSPPRRPRVCSRRRSPRAHRRHRSTTR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable esterase pseudogene,
Sanger Rv1104, Tigr MT1136

540 bp forward orf at  [03:21]

-> Mtbook page 381

probable esterase pseudogene

Function

Classification II. B.5
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 5. Esterases and lipases

Protein

180 aminoacids, 20,1 kDa

>Rv1105 CRSPRAITSMFTQIAAEQPDLQVPTEEQIGSAYSRWRRKARSLSMATDVGFRMPSVWLAEGHSGVAPVYLYRFDYSTPLLKLLLVRAAHATELPYVWGNLGGSQDPALKLGDAKAAIAVSRRVRTRWINFATRGKPTGPDGEPDWPCYEEAHRACLIIGRRDAVVHDVDAHIRATWGSKW*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable esterase pseudogene ,
Sanger Rv1105, Tigr MT1136

1110 bp reverse orf at  [03:21]

-> Mtbook page 381

probable cholesterol dehydrogenase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

370 aminoacids, 40,7 kDa

>Rv1106c MLRRMGDASLTTELGRVLVTGGAGFVGANLVTTLLDRGHWVRSFDRAPSLLPAHPQLEVLQGDITDADVCAAAVDGIDTIFHTAAIIELMGGASVTDEYRQRSFAVNVGGTENLLHAGQRAGVQRFVYTSSNSVVMGGQNIAGGDETLPYTDRFNDLYTETKVVAERFVLAQNGVDGMLTCAIRPSGIWGNGDQTMFRKLFESVLKGHVKVLVGRKSARLDNSYVHNLIHGFILAAAHLVPDGTAPGQAYFINDAEPINMFEFARPVLEACGQRWPKMRISGPAVRWVMTGWQRLHFRFGFPAPLLEPLAVERLYLDNYFSIAKARRDLGYEPLFTTQQALTECLPYYVSLFEQMKNEARAEKTAATVKP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable cholesterol dehydrogenase,
Sanger Rv1106c, Tigr MT1137

255 bp reverse orf at  [03:21]

-> Mtbook page 381

xseB

exonuclease VII small subunit

Function

Classification II. B.2
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 2. DNA

Protein

85 aminoacids, 9,3 kDa

>Rv1107c MVCDPNGDDTGRTHATVPVSQLGYEACRDELMEVVRLLEQGGLDLDASLRLWERGEQLAKRCEEHLAGARQRVSDVLAGDEAQNG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: xseB, xseB and M. tuberculosis,
exonuclease VII small subunit ,
Sanger Rv1107c, Tigr MT1138

1245 bp reverse orf at  [03:21]

-> Mtbook page 381

xseA

exonuclease VII large subunit

Function

Classification II. B.2
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 2. DNA

Protein

415 aminoacids, 44,6 kDa

>Rv1108c VTQNSAENPFPVRAVAIRVAGWIDKLGAVWVEGQLAQITMRPDAKTVFMVLRDPAADMSLTVTCSRDLVLSAPVKLAEGVQVVVCGKPSFYTGRGTFSLRLSEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKRPIPYLPNMIGLITGRASAAERDVTTVASARWPAARFAVRNVAVQGPNAVGQIVEALRELDRDPDVDVIVLARGGGSVEDLLPFSDETLCRAIAACRTPVVSAVGHEPDNPLCDLVVDLRAATPTDAAKKVVPDTAAEQRLIDDLRRRSAQALRNWVSREQRAVAQLRSRPVLADPMTMVSVRAEEVHRARSTLRRNLTLMVAAETERIGHLAARLATLGPAATLARGYAIVQTVAQTGPEGGSEPQVLRSVHDAPEGTKLRVRVADGALAAVSEGQTNGL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: xseA, xseA and M. tuberculosis,
exonuclease VII large subunit,
Sanger Rv1108c, Tigr MT1139

636 bp reverse orf at  [03:21]

-> Mtbook page 382

Function

unknown

Protein

212 aminoacids, 23 kDa

>Rv1109c MATAPYGVRLLVGAATVAVEETMKLPRTILMYPMTLASQAAHVVMRFQQGLAELVIKGDNTLETLFPPKDEKPEWATFDEDLPDALEGTSIPLLGLSDASEAKNDDRRSDGRFALYSVSDTPETTTASRSADRSTNPKTAKHPKSAAKPTVPTPAVAAELDYPALTLAQLRARLHTLDVPELEALLAYEQATKARAPFQTLLANRITRATAK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1109c, Tigr MT1140

1005 bp forward orf at  [03:21]

-> Mtbook page 382

lytB'

very similar to LytB

Function

Classification II. C.3
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 3. Murein sacculus and peptidoglycan

Protein

335 aminoacids, 36,3 kDa

>Rv1110 MVPTVDMGIPGASVSSRSVADRPNRKRVLLAEPRGYCAGVDRAVETVERALQKHGPPVYVRHEIVHNRHVVDTLAKAGAVFVEETEQVPEGAIVVFSAHGVAPTVHVSASERNLQVIDATCPLVTKVHNEARRFARDDYDILLIGHEGHEEVVGTAGEAPDHVQLVDGVDAVDQVTVRDEDKVVWLSQTTLSVDETMEIVGRLRRRFPKLQDPPSDDICYATQNRQVAVKAMAPECELVIVVGSRNSSNSVRLVEVALGAGARAAHLVDWADDIDSAWLDGVTTVGVTSGASVPEVLVRGVLERLAECGYDIVQPVTTANETLVFALPRELRSPR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lytB', lytB' and M. tuberculosis,
very similar to LytB,
Sanger Rv1110, Tigr MT1141

912 bp reverse orf at  [03:21]

-> Mtbook page 382

Function

unknown

Protein

304 aminoacids, 34,5 kDa

>Rv1111c VPWWAAILIAVTATAIGYAIDAGSGHKALTLVFTGCYIAGCVGAVLAVRQSDLFTALVQPPLILFCAVPGAYWLFHGGTIGKFKDLLINCGYSLIERFPLMLGTAAGVLLIGLVRWYLGTALFDSIARKLSSLMTGDSDDDGGRRSAQRPARTRSRHARPPSEDNREPIAERRSRRRPRPQNDPHPRRNAHERPAPRSSRFDSYRSYQPSEPSGPAEPVNRYERRGARYQPYARYEPTYEPQRRRARPSEPTNPTHHPISQVRYRGSATRDARRDNYREEQRFDRRDRSRAPRRPPAESWEYDV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1111c, Tigr MT1142

1071 bp forward orf at  [03:22]

-> Mtbook page 383

Function

unknown

Protein

357 aminoacids, 38,1 kDa

>Rv1112 VSLSLGIVGLPNVGKSTLFNALTRNNVVAANYPFATIEPNEGVVSLPDPRLDKLAELFGSQRVVPAPVTFVDIAGLVKGASEGAGLGNKFLAHIRECDAICQVVRVFVDDDVTHVTGRVDPQSDIEVVETELILADLQTLERATGRLEKEARTNKARKPVYDAALRAQQVLDAGKTLFAAGVDAAALRELNLLTTKPFLYVFNADEAVLTDPARVGELRALVAPADAVFLDAAIESELTELDDESAAELLESIGQSERGLDALARAGFHTLKLQTFLTAGPKEARAWTIHQGDTAPKAAGVIHSDFEKGFIKAEIVSYDDLVAAGSMAAAKAAGKVRIEGKDYVMADGDVVEFRFNV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1112, Tigr MT1143

195 bp forward orf at  [03:22]

-> Mtbook page 383

Function

unknown

Protein

65 aminoacids, 7 kDa

>Rv1113 MRTTVTVDDALLAKAAELTGVKEKSTLLREGLQTLVRVESARRLAALGGTDPQATAAPRRRTSPR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1113

372 bp forward orf at  [03:22]

-> Mtbook page 383

Function

unknown

Protein

124 aminoacids, 13,4 kDa

>Rv1114 VILVDTSVWIEHLRAADARLVELLGDDEAGCHPLVIEELALGSIKQRDVVLDLLANLYQFPVVTHDEVLRLVGRRRLWGRGLGAVDANLLGSVALVGGARLWTRDKRLKAACAESGVALAEEVS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1114, Tigr MT1144

696 bp forward orf at  [03:22]

-> Mtbook page 383

Function

unknown

Protein

232 aminoacids, 24,1 kDa

>Rv1115 VISTTRIDFLWILSVAFASMIALATLLTLINQVVGTPYIPGGDSPAGTDCSELASWVSNAATARPVFGDRFNTGNEEAALAARGFQQGTAPNALVIGWNGHHTAVTLPDGTPVSSGEGGGVRVGGGGAYQPKFTHHMYLPMDVDAGEDQPPAPDEPVTAVDDVEPEMPAPCPTQRPPVTPRHNLCNKLRTMPGALSAALAAAAPVWPAPISGCRGFSTSLLAKRNHPVIVGK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1115, Tigr MT1145

183 bp forward orf at  [03:22]

-> Mtbook page 384

Function

unknown

Protein

61 aminoacids, 7,3 kDa

>Rv1116 MCSRMADEPRLEAGAHPFEEGRDKAPELRATQMDHVRFTEGRRERNRDRLERSQQFRQPGR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1116, Tigr MT1146

321 bp forward orf at  [03:22]

-> Mtbook page 384

Function

unknown

Protein

107 aminoacids, 12,1 kDa

>Rv1117 MIFIVVKFETKPEWTERWPDLVASFTAATRAEEGNLWFEWSRSLDDPAEYVLVESFRDGEAGGVHVNSDHFRQAMRELPKALASTPKIISQTIDATGWSAMGEMTVG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1117, Tigr MT1149

858 bp reverse orf at  [03:22]

-> Mtbook page 384

Function

unknown

Protein

286 aminoacids, 32,2 kDa

>Rv1118c VQSGPHLVGRVGTSFPLIARHQGATRDDAGDTGQPDPLPHVAHPDRLYPPMVHGVDPSTLALDRALNETRTGDLWLFRGRSRPDRAIQTLTNAPVNHVGMTVAIDDLPPLIWHAELGDKLLDVWTGTNHRGVQLNDARQVVQQWAGRYRQRCWLRQLTPHANRDQEDKLLRVIARMNGTPFPTTARLTGRWLRGRLPTLNDWLRGIPVLDRKVREQTQRRKQQQRTMGLATAYCAETVAITYEEMGLLVTDKDAHWFDPGKFWSGDSLPLAPGYRLGHEIAVDVGG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1118c, Tigr MT1150

147 bp reverse orf at  [03:22]

-> Mtbook page 384

Function

unknown

Protein

49 aminoacids, 5,1 kDa

>Rv1119c MTARVAGQAVGGQILVGEPVHDAVSDCADIRFGSYRLFSLDAAPGPDLD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1119c, Tigr MT1151

492 bp reverse orf at  [03:22]

-> Mtbook page 384

Function

unknown

Protein

164 aminoacids, 18,1 kDa

>Rv1120c MLSGGREAVKTVWQTANLVRKEGFGAAVRSSIEDPADWAEVERPDLARVTPDGRVVILFSDIEESTALDERIGDRTWVKLIGAHDKLVHELVRRWSGHMVTSQGDGFMIAFARAEQAVRCGIDIQDALRNSAKRKRNQGIRVRIGTTWGARCGTVTICSAATSQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1120c, Tigr MT1152

1398 bp forward orf at  [03:22]

-> Mtbook page 384

zwf

glucose-6-phosphate 1-dehydrogenase

Function

Classification I. B.5
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 5. Pentose phosphate pathway

Protein

466 aminoacids, 52,2 kDa

>Rv1121 LVDGGGGASDLLVIFGITGDLARKMTFRALYRLERHQLLDCPILGVASDDMSVGQLVKWARESIGRTEKIDDAVFDRLAGRLSYLHGDVTDSQLYDSLAELIGSACRPLYYLEMPPALFAPIVENLANVRLLERARVAVEKPFGHDLASALELNARLRAVLGEDQILRVDHFLGKQPVVELEYLRFANQALAELWDRNSISEIHITMAEDFGVEDRGKFYDAVGALRDVVQNHLLQVLALVTMEPPVGSSADDLNDKKAEVFRAMAPLDPDRCVRGQYLGYTEVAGVASDSATETYVALRTEIDNWRWAGVPIFVRAGKELPAKVTEVRLFLRRVPALAFLPNRRPAEPNQIVLRIDPDPGMRLQISAHTDDSWRDIHLDSSFAVDLGEPIRPYERLLYAGLVGDHQLFAREDSIEQTWRIVQPLLDNPGEIHRYDRGSWGPEAAQSLLRGHRGWQSPWLPRGTDA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: zwf, zwf and M. tuberculosis,
glucose-6-phosphate 1-dehydrogenase,
Sanger Rv1121, Tigr MT1153

1020 bp forward orf at  [03:23]

-> Mtbook page 385

gnd2

6-phosphogluconate dehydrogenase (Gram +)

Function

Classification I. B.5
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 5. Pentose phosphate pathway

Protein

340 aminoacids, 36,4 kDa

>Rv1122 MQLGMIGLGRMGANIVRRLAKGGHDCVVYDHDPDAVKAMAGEDRTTGVASLRELSQRLSAPRVVWVMVPAGNITTAVIEELANTLEAGDIVIDGGNTYYRDDLRHEKLLFKKGIHLLDCGTSGGVWGRERGYCLMIGGDGDAFARAEPIFATVAPGVAAAPRTPGRDGEVAPSEQGYLHCGPCGSGHFVKMVHNGIEYGMMASLAEGLNILRNADVGTRVQHGDAETAPLPNPECYQYDFDIPEVAEVWRRGSVIGSWLLDLTAIALRESPDLAEFSGRVSDSGEGRWTAIAAIDEGVPAPVLTTALQSRFASRDLDDFANKALSAMRKQFGGHAEKPAN*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: gnd2, gnd2 and M. tuberculosis,
6-phosphogluconate dehydrogenase (Gram +),
Sanger Rv1122, Tigr MT1054

906 bp reverse orf at  [03:23]

-> Mtbook page 385

bpoB

probable non-heme bromoperoxidase

Function

Classification III. F
Category III. Cell processes
Class F. Detoxification

Protein

302 aminoacids, 32,5 kDa

>Rv1123c MTIWRVPSKVTSGPVSAVSSSPQAVAFSGARGITLVADEWNRGAAAADRPTILMLHGGGQNRFSWKNTGQILADEGHHVVALDTRGPGDSDRAPGADYAVETPTTDVLHVVEAIGRRVVVVEASMGGLTGILVAERAGPQTVNGLVLVDVVPRYEKEGNARIRDFMLGNIDGFGSLEEAADAVAEYLPHRDKPRSPEGLKRNLRLRDGRWHWHWDPAMMTAPGHDPQLRTENFERAAMGLTIPVLLIRGKLSDVVSSDGARDFLAKVPNAEFVELSNAGRTAAGDDNDAFTDVVVDFVRRLS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: bpoB, bpoB and M. tuberculosis,
probable non-heme bromoperoxidase,
Sanger Rv1123c, Tigr MT1155

948 bp forward orf at  [03:23]

-> Mtbook page 385

ephC

probable epoxide hydrolase

Function

Classification III. F
Category III. Cell processes
Class F. Detoxification

Protein

316 aminoacids, 34,7 kDa

>Rv1124 MRAGRGERESTWRTTMAEPHWIDVKGPNGDLKALTWGPAGAPVALCLHGFPDTAYGWRKVAPRLAESGWHVVAPFMRGYAPSSIPADGSYHVGALMHDALRVRSAAGGTERDVIIGHDWGAIAATGLAAMPDSPFAKAVIMSVPPSAAFRPLGRVPERGRLLRELPHQLLRSWYILYFQLPWLPERSASWVVPLLWRRWSPGYHAEEDLRHVDAAIGTPEGRRAALGPYRATMRNTRAPADYADLNRLWTEAPKLPVLYLHGHDDGCATSAFTHWTARVLPAGSEVAVVEHAGHFLQLEQPDKIAELIVAFIGSPG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ephC, ephC and M. tuberculosis,
probable epoxide hydrolase,
Sanger Rv1124, Tigr MT1156

1242 bp forward orf at  [03:23]

-> Mtbook page 386

Function

unknown

Protein

414 aminoacids, 44,2 kDa

>Rv1125 VAGHRMAAVDAQFYWMSAKVPNDQFLLYAFDGEPTDLERAVAQVYRRARGCPGLGMRVQDRGALAYPQWVPTPVQRDQLVCHDLADRSWQGCLAAVVGLASKQLDMRRMPWRLHVFTPVHDVPGVSGLGTVAVMQFAHALGDGARASAMAAWLFGRPAAVPEIARSRAGFLPWRAAHAARAHLRLVRDTNAGLVAPGVGSRPPLSTNARPEGVRAVRTLLRRRSQLAGPTVTVTVLAAVSTGLLGLLGGDVDTLGAEVPMAKPGVPRSYNHFGNVVVGLYPRLEPDERVRRIATDLANARRRFEHPAMLSADRAFAAVPAALLRWGVSQFDAEVRPVRVAGNTVVSSVYRGAADLSFGDAPVVLTAGYPALSPAMGLTHGVHGIGDTVAISVHAAESAVSDIDAYMRLLDAALQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1125, Tigr MT1157

603 bp reverse orf at  [03:23]

-> Mtbook page 386

Function

unknown

Protein

201 aminoacids, 22,2 kDa

>Rv1126c MSELTVLQAVRLKGRVITTDLAQTLGEDLADVAATVDRLTAAGLLVDATPLRISPSGRMRLDDLLAEERNRADSTVLAAAYRDFRSVNADFKRLVTDWQLKGEKPNTHDDAEYDAAVLSRLDGVHRRVGPIIGTVAMQLPRLSRYPVKLRAALDKVKAGDIAWLTRPLIDSYHTVWFELHEELIQAVGLTRDEAAKSGDAQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1126c, Tigr MT1158

1470 bp reverse orf at  [03:23]

-> Mtbook page 386

ppdK

similar to pyruvate, phosphate dikinase

Function

Classification I. C.1
Category I. Small-molecule metabolism
Class C. Central intermediary metabolism
Group 1. General

Protein

490 aminoacids, 52 kDa

>Rv1127c MTRITRANGCPDGTLENAVVALDGGANYPREILGNKGHGIDMMRRHHLPVPPAFCITTEVGVRYLAAPGSTIAAIWDDVLDRMSWLETETSCTFGRGPNPLLVSVRSGATQSMPGMMDTILDVGMTDAVERVLARPGAADFAHDTRRRFTSMYRRIVGSAGPITDDPYAQLRASIEAVFASWNSPRAVAYRDHHGLDDQGGTAVVVQAMVFGNLTANSGAGVLSSRNPITGANEPFGEWLPGGQGDDVVSGLVAVAPITALRDQQPAVYDQLMAAARSLERMAGDVQEIEFTVEDSQLWLLQTRGAERSAQAAVRLALQLHHEGLIDDTETLRRVTPTHIETLLRPSLQTETRLAAPLLAKGLPACPGVVSGTAYTEVDEALDAADRGEPVILVRDHTRPEDVMGMLAAQGIVTEVGGAASHAAVVSRELGRVAVVGCGPGVAAALAGKEITVDGYEGEVRQGVLALSAWSESDTPELRELADIAQRISS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ppdK, ppdK and M. tuberculosis,
similar to pyruvate, phosphate dikinase ,
Sanger Rv1127c, Tigr MT1159

1353 bp reverse orf at  [03:24]

-> Mtbook page 387

REP

Function

Classification IV. B.2
Category IV. Other
Class B. IS elements, Repeated sequences, and Phage
Group 2.REP13E12 family (10)

Protein

451 aminoacids, 49,3 kDa

>Rv1128c MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCETARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADRLRITRSEAKRRVAEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPSWVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDGDYTDEDRARRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQKAPCVNGAPSKEQARRDTRSCPQRNHDALNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAAGAGLTGGGTILPISDVIRLARHANHYLAIFDRGKALALYHTKRLASPAQRIMLYAKDSGCSAPGCDVPGYYCEVHHVTPYAQCRNTDVNDLTLGCGGHHPLAERGWTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLLADDEGDP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: REP, REP and M. tuberculosis,
Sanger Rv1128c, Tigr MT1160

1458 bp reverse orf at  [03:24]

-> Mtbook page 387

transcriptional regulator (PbsX/Xre family)

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

486 aminoacids, 54,1 kDa

>Rv1129c MTRSNVLPVARTYSRTFSGARLRRLRQERGLTQVALAKALDLSTSYVNQLENDQRPITVPVLLLLTERFDLSAQYFSSDSDARLVADLSDVFTDIGVEHAVSGAQIEEFVARMPEVGHSLVAVHRRLRAATEELEGYRSRATAETELPPARPMPFEEVRDFFYDRNNYIHDLDMAAERMFTESGMRTGGLDIQLAELMRDRFGISVVIDDNLPDTAKRRYHPDTKVLRVAHWLMPGQRAFQIATQLALVGQSDLISSIVATDDQLSTEARGVARIGLANYFAGAFLLPYREFHRAAEQLRYDIDLLGRRFGVGFETVCHRLSTLQRPRQRGIPFIFVRTDKAGNISKRQSATAFHFSRVGGSCPLWVVHDAFAQPERIVRQVAQMPDGRSYFWVAKTTAADGLGYLGPHKNFAVGLGCDLAHAHKLVYSTGVVLDDPSTEVPIGAGCKICNRTSCAQRAFPYLGGRVAVDENAGSSLPYSSTEQSV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

transcriptional regulator (PbsX/Xre family),
Sanger Rv1129c

1578 bp forward orf at  [03:24]

-> Mtbook page 388

Function

unknown

Protein

526 aminoacids, 57,8 kDa

>Rv1130 VPDQDTKVRFFRVFCWCPVLRMVRIMLMHAVRAWRSADDFPCTEHMAYKIAQVAADPVDVDPEVADMVCNRIIDNAAVSAASMVRRPVTVARHQALAHPVRHGAKVFGVEGSYSADWAAWANGVAARELDFHDTFLAADYSHPADNIPPLVAVAQQLGVCGAELIRGLVTAYEIHIDLTRGICLHEHKIDHVAHLGPAVAAGIGTMLRLDQETIYHAIGQALHLTTSTRQSRKGAISSWKAFAPAHAGKVGIEAVDRAMRGEGSPAPIWEGEDGVIAWLLAGPEHTYRVPLPAPGEPKRAILDSYTKQHSAEYQSQAPIDLACRLRERIGDLDQIASIVLHTSHHTHVVIGTGSGDPQKFDPDASRETLDHSLPYIFAVALQDGCWHHERSYAPERARRSDTVALWHKISTVEDPEWTRRYHCADPAKKAFGARAEVTLHSGEVIVDELAVADAHPLGTRPFERKQYVEKFTELADGVVEPVEQQRFLAVVESLADLESGAVGGLNVLVDPRVLDKAPVIPPGIFR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1130, Tigr MT1162

1179 bp forward orf at  [03:25]

-> Mtbook page 388

gltA1

citrate synthase 3

Function

Classification I. B.3
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 3. TCA cycle

Protein

393 aminoacids, 43 kDa

>Rv1131 MTGPLAAARSVAATKSMTAPTVDERPDIKKGLAGVVVDTTAISKVVPQTNSLTYRGYPVQDLAARCSFEQVAFLLWRGELPTDAELALFSQRERASRRVDRSMLSLLAKLPDNCHPMDVVRTAISYLGAEDPDEDDAAANRAKAMRMMAVLPTIVAIDMRRRRGLPPIAPHSGLGYAQNFLHMCFGEVPETAVVSAFEQSMILYAEHGFNASTFAARVVTSTQSDIYSAVTGAIGALKGRLHGGANEAVMHDMIEIGDPANAREWLRAKLARKEKIMGFGHRVYRHGDSRVPTMKRALERVGTVRDGQRWLDIYQVLAAEMASATGILPNLDFPTGPAYYLMGFDIASFTPIFVMSRITGWTAHIMEQATANALIRPLSAYCGHEQRVLPGTF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: gltA1, gltA1 and M. tuberculosis,
citrate synthase 3,
Sanger Rv1131, Tigr MT1163

1728 bp forward orf at  [03:25]

-> Mtbook page 389

possible transporter

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

576 aminoacids, 64 kDa

>Rv1132 MGFLQPRLPDIDLAEWSQGSRSQKIRPMAQHWAEVGFGTPVLLHLFYVAKILLYVLVGWLIVLTTKGIDGFTDAAAWYAEPIVFEKVVLYTMLFEVIGLGCGFGPLNNRFFPPMGSILYWMRFGTIRLPPWPDRVPWTRGTKRKPVDVALYALLVMMLLSALFTDGAGPIPELGTTVGLLPAWQIVLILLLLGVLGLRDKVIFLAARGEVYATLTVTFLFGRLNGIDMIVAAKLVFLVIWIGAATSKLNRHFPFVISTMMSNNPLFRPRFIKRMFFKKFPGDLRPGLLSRIVAHVSTVIEMCVPVVLFVAHGGWPTVVAATIMVCFHLGILTAIPMGVPLEWNVFMIFGVLSLFVGHACLGLADVKNPVPLAILIAVVAGIVIAGNVFPRKISFLAAMRYYAGNWDTTLWCIKPSAEDKINRGIVAIASMPAAQLERFYGKDRAQIPMYLGYAFRAMNSHGRALFTLAHRAMAGHDEDDYVITDGERVCSTAVGWNFGDGHLHNEQLIAAMQQRCGFQPGEVRVVLLDAQPIHRQTQEYRLVDAATGEFERGYVRVADMVNRQPWDDDVPVHVLPG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible transporter,
Sanger Rv1132, Tigr MT1164

2277 bp reverse orf at  [03:25]

-> Mtbook page 389

metE

5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase

Function

Classification I. D.2
Category I. Small-molecule metabolism
Class D. Amino acid biosynthesis
Group 2. Aspartate family

Protein

759 aminoacids, 81,6 kDa

>Rv1133c VTQPVRRQPFTATITGSPRIGPRRELKRATEGYWAGRTSRSELEAVAATLRRDTWSALAAAGLDSVPVNTFSYYDQMLDTAVLLGALPPRVSPVSDGLDRYFAAARGTDQIAPLEMTKWFDTNYHYLVPEIGPSTTFTLHPGKVLAELKEALGQGIPARPVIIGPITFLLLSKAVDGAGAPIERLEELVPVYSELLSLLADGGAQWVQFDEPALVTDLSPDAPALAEAVYTALCSVSNRPAIYVATYFGDPGAALPALARTPVEAIGVDLVAGADTSVAGVPELAGKTLVAGVVDGRNVWRTDLEAALGTLATLLGSAATVAVSTSCSTLHVPYSLEPETDLDDALRSWLAFGAEKVREVVVLARALRDGHDAVADEIASSRAAIASRKRDPRLHNGQIRARIEAIVASGAHRGNAAQRRASQDARLHLPPLPTTTIGSYPQTSAIRVARAALRAGEIDEAEYVRRMRQEITEVIALQERLGLDVLVHGEPERNDMVQYFAEQLAGFFATQNGWVQSYGSRCVRPPILYGDVSRPRAMTVEWITYAQSLTDKPVKGMLTGPVTILAWSFVRDDQPLADTANQVALAIRDETVDLQSAGIAVIQVDEPALRELLPLRRADQAEYLRWAVGAFRLATSGVSDATQIHTHLCYSEFGEVIGAIADLDADVTSIEAARSHMEVLDDLNAIGFANGVGPGVYDIHSPRVPSAEEMADSLRAALRAVPAERLWVNPDCGLKTRNVDEVTASLHNMVAAAREVRAG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: metE, metE and M. tuberculosis,
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase,
Sanger Rv1133c, Tigr MT1165

234 bp forward orf at  [03:25]

-> Mtbook page 390

Function

unknown

Protein

78 aminoacids, 8,2 kDa

>Rv1134 MAAYQKFGQEHAAAIRGGAVLHPTATATTVRVTGARGGDVVTGDGPYEAADLDEQGPFPMETVYLWEDGPNGTTRMTL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv1134, Tigr MT1167

1854 bp reverse orf at  [03:26]

-> Mtbook page 390

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

618 aminoacids, 60,2 kDa

>Rv1135c MSFLVLPPEVNSALMFAGAGSGPTLAAAAAWDGLAAELGQAANSFSSATAALADTAWQGPAATAMAAAAAPYASWLSTAATRALSAAAQAKAAAAVYEAARAATVDPLLVAANRHQLVSLVLSNLFGQNAPAIAATEAAYEQLWAADVAAMVSYHSGASAVAAQLAPWAQAVRALPNPTAPALASGPAALAIPALGIGNTGIGNIFSIGNIGDYNLGNGNTGNANLGSGNTGQANLGSGNTGFFNFGSGNTANTNFGSGNLGNLNLGSGNDGNGNFGLGNIGDGNRGSGNVGSFNFGTANAGSFNVGSANHGSPNVGFANLGNNNLGIANLGNNNLGIANLGNNNIGIGLTGDNMIGIGALNSGIGNLGFGNSGNNNIGLFNSGNNNIGFFNSGDSNFGFFNSGDTNTGFGNAGFTNTGFGNAGSGNFGFGNAGNNNFGFGNSGFENMGVGNSGAYNTGSFNSGTLNTGDLNSGDFNTGWANSGDINTGGFHSGDLNTGFGSPVDQPVMNSGFGNIGTGNSGFNNSGDANSGFQNTNTGAFFIGHSGLLNSGGGQHVGISNSGTGFNTGLFNTGFNNTGIGNSATNAAFTTTSGVANSGDNSSGGFNAGNDQSGFFDG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv1135c, Tigr MT1168