1620 bp reverse orf at  [02:23]

-> Mtbook page 271

multidrug resistance protein

Function

Classification III. A.6
Category III. Cell processes
Class A. Transport/binding proteins
Group 6. Efflux proteins

Protein

540 aminoacids, 56,6 kDa

>Rv0783c MLGNAMVEACPAEGDAPVPITPAGRPRSGQRSYPDRLDVGLLRTAGVCVLASVMAHVDVTVVSVAQRTFVADFGSTQAVVAWTMTGYMLALATVIPTAGWAADRFGTRRLFMGSVLAFTLGSLLCAVAPNILLLIIFRVVQGFGGGMLTPVSFAILAREAGPKRLGRVMAVVGIPMLLGPVGGPILGGWLIGAYGWRWIFLVNLPVGLSALVLAAIVFPRDRPAASENFDYMGLLLLSPGLATFLFGVSSSPARGTMADRHVLIPAITGLALIAAFVAHSWYRTEHPLIDMRLFQNRAVAQANMTMTVLSLGLFGSFLLLPSYLQQVLHQSPMQSGVHIIPQGLGAMLAMPIAGAMMDRRGPAKIVLVGIMLIAAGLGTFAFGVARQADYLPILPTGLAIMGMGMGCSMMPLSGAAVQTLAPHQIARGSTLISVNQQVGGSIGTALMSVLLTYQFNHSEIIATAKKVALTPESGAGRGAAVDPSSLPRQTNFAAQLLHDLSHAYAVVFVIATALVVSTLIPAAFLPKQQASHRRAPLLSA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

multidrug resistance protein,
Sanger Rv0783c, Tigr MT0807

684 bp forward orf at  [02:23]

-> Mtbook page 272

Function

unknown

Protein

228 aminoacids, 25 kDa

>Rv0784 VSVSGIGESTLADVDAFCAEMDARSVPVSLLVAPRMRDDYRLDRDPRTVDWLTGRRAAGDALVLHGYDEAATKRRRGEFAMLRAHEANLRLMAADRVLEHLGLRTRLFAAPGWLVSPGVRTALPANGFRLLADLHGITDLVRLTTVRARVLGIGEGFLAEPWWCRMVVMSAERIARRGGVVRIAVAARHLRKSGPLQAMLDAVDLAMLQGCTPMVYRWRADAAVLDAA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0784, Tigr MT0808

1698 bp forward orf at  [02:23]

-> Mtbook page 272

putative dehydrogenases

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

566 aminoacids, 61,2 kDa

>Rv0785 VALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLILDQENRANVGGQAFWSFGGLFLVNSPEQRRLGIRDSHELALQDWLGTAAFDRPEDYWPEQWAHAYVDFAAGEKRSWLRARGLKIFPLVGWAERGGYDAQGHGNSVPRFHITWGTGPALVDIFVRQLRDRPTVRFAHRHQVDKLIVEGNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVASGGIGGNHELVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVINPDRMWHYTEGITNYDPIWPRHGIRIIPGPSSLWLDAAGKRLPVPLFPGFDTLGTLEYITKSGHDYTWFVLNAKIIEKEFALSGQEQNPDLTGRRLGQLLRSRAHAGPPGPVQAFIDRGVDCVHANSLRELVAAMNELPDVVPLDYETVAAAVTARDREVVNKYSKDGQITAIRAARRYRGDRFGRVVAPHRLTDPKAGPLIAVKLHILTRKTLGGIETDLDARVLKADGTPLAGLYAAGEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGAAEDIR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative dehydrogenases,
Sanger Rv0785, Tigr MT0809

387 bp reverse orf at  [02:23]

-> Mtbook page 272

Function

unknown

Protein

129 aminoacids, 13,9 kDa

>Rv0786c VHVGDELPLAELTVRAVGGCHAVIHPEIPVIENISYLVGDSKHRARLMHPGDALFVPGEQVDVLATPAAAPWMKISEAVDYLRAVAPARAVPIHQAIVAPDARGIYYGRLTEMTTTDFQVLPEESAVTF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0786c, Tigr MT0810

957 bp forward orf at  [02:23]

-> Mtbook page 273

Function

unknown

Protein

319 aminoacids, 34,2 kDa

>Rv0787 VHRPPWLAQLRRRLRIGVQLGSRVVLEQGRQPRDVYVIGVLVGDQDRGQTGDSLEAVRESTGIEEQAGLTELSEEAGMAEMRELHVYDCALMGAFPMRLILATMLVAGRLLATLMAAPSAQAEPETCPPICDQIPATAWISTHAVPLNSQYRWPAMAGAAVAVTRATPRFGFEQVCATPAFPHDSRDWAVAGRVTVVHPDGQWQLQAQVLHWRGDTARGGQIAASVFGTAVAALRACQLGAPLQSPSVTDDEPTRMAAVISGPVIMYTYLVAHVSSSTISELTLWSSGPPQVPWPTVADSAVLDALTAPLCEAYIGSCP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0787, Tigr MT0811

672 bp forward orf at  [02:24]

-> Mtbook page 273

purQ

phosphoribosylformylglycin-amidine synthase I

Function

Classification I. F.1
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 1. Purine ribonucleotide biosynthesis

Protein

224 aminoacids, 23,6 kDa

>Rv0788 VTARIGVVTFPGTLDDVDAARAARQVGAEVVSLWHADADLKGVDAVVVPGGFSYGDYLRAGAIARFAPVMDEVVAAADRGMPVLGICNGFQVLCEAGLLPGALTRNVGLHFICRDVWLRVASTSTAWTSRFEPDADLLVPLKSGEGRYVAPEKVLDELEGEGRVVFRYHDNVNGSLRDIAGICSANGRVVGLMPHPEHAIEALTGPSDDGLGLFYSALDAVLTG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: purQ, purQ and M. tuberculosis,
phosphoribosylformylglycin-amidine synthase I,
Sanger Rv0788, Tigr MT0813

597 bp reverse orf at  [02:24]

-> Mtbook page 273

Function

unknown

Protein

199 aminoacids, 22,5 kDa

>Rv0789c VSRRAIHSGRAAPRRSGNSHLVLRNRVPSSKDSPRRRPHHEFMTESIGEPLSTNLIERYLRARGRRYFRGHHDAEFFFVANAHLRLHVHLEISPAYRDVFTIRVSPAYFFPATDHTRLAEIVNAWNLQNHEVTAIVHGSSDPHRIGVAAERSLIRDRIRFDDFATFVDNAVSAATELFGQLTAAGLPPTATPPLLRDAG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0789c, Tigr MT0814

726 bp reverse orf at  [02:24]

-> Mtbook page 273

Function

unknown

Protein

242 aminoacids, 26,7 kDa

>Rv0790c MTLANNGTGMDHFLTPTEYLDAGHPLVRTTAATLIRDAVSDTERVRRIYYYVRDVPYDVLASFRYLAQGHHRASDVIGHGVAFCMGKASSFVALCRAAGVPARIAFQTIDAPDKEFLSPQVRALWGGRTGRPFPWHSLGEAYLGRRWVKLDATIDAPTAARLGKPYRQEFDGATPIPTVEGTILRENGSYADYPSAVAQWYERIAQSVLKALQSTEVHALVAADEELWTGPPVELADATHRL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0790c, Tigr MT0815

1041 bp reverse orf at  [02:24]

-> Mtbook page 274

possible monooxygenasemonoxygenase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

347 aminoacids, 37,7 kDa

>Rv0791c MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTAEEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSRSLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQGRLDLGLGAGWFRRESQAYGIPFPPVGDRVSALAESLQVIKAVWTEPNPTYAGRFYTLDGATCDPPPVQRPHPPLWIGGEGDRVQRIAAKHAQGLNVRWWSPQQVTQRRGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEEVRIREEFASIPEPGLIVGTPDRCVERIREYQDRGVGHFLFTIPHVVKSDYLHIIGSDIIPRVKTEVTIP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible monooxygenasemonoxygenase,
Sanger Rv0791c, Tigr MT0816

807 bp reverse orf at  [02:24]

-> Mtbook page 274

transcriptional regulator (GntR family)

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

269 aminoacids, 29 kDa

>Rv0792c MTSVKLDLDAADLRISRGSVPASTQLAEALKAQIIQQRLPRGGRLPSERELIDRSGLSRVTVRAAVGMLQRQGWLVRRQGLGTFVADPVEQELSCGVRTITEVLLSCGVTPQVDVLSHQTGPAPQRISETLGLVEVLCIRRRIRTGDQPLALVTAYLPPGVGPAVEPLLSGSADTETTYAMWERRLGVRIAQATHEIHAAGASPDVADALGLAVGSPVLVVDRTSYTNDGKPLEVVVFHHRPERYQFSVTLPRTLPGSGAGIIEKRDFA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

transcriptional regulator (GntR family),
Sanger Rv0792c

303 bp forward orf at  [02:24]

-> Mtbook page 274

Function

unknown

Protein

101 aminoacids, 11,2 kDa

>Rv0793 MTSPVAVIARFMPRPDARSALRALLDAMITPTRAEDGCRSYDLYESADGGELVLFERYRSRIALDEHRGSPHYLNYRAQVGELLTRPVAVTVLAPLDEASA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0793

1497 bp reverse orf at  [02:24]

-> Mtbook page 274

lpdB

dihydrolipoamide dehydrogenase

Function

Classification I. B.3
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 3. TCA cycle

Protein

499 aminoacids, 52,5 kDa

>Rv0794c MTAAQQDQAPMATPGCREGETYDVVVLGAGPVGQNVADRARAGGLRVAVVERELVGGECSYWACVPSKALLRPVIAISDARRVDGAREAVDGSINTAGVFGRRNRYVAHWDDTGQADWVSGIGATLIRGDGRLDGPRRVVVTKSSGESVALTARHAVVICTGSRPALPDLPGITEARPWTNRQATDNSTVPDRLAIVGAGGVGVEMATAWQGLGASVTLLARGSGLLPRMEPFVGELIGRGLADAGVDVRVGVSVRALGRPNPTGPVVLELDDGTELRVDEVLFATGRAPRTDDIGLETIGLTPGSWLDVDDTCRVRAVDDGWLYAAGDVNHRALLTHQGKYQARIAGTAIGARAAGRPLDTTSWGMHATTADHHAVPQAFFTDPEAAAVGLTADQAAQAGHRIKAIDVEIGDVVMGAKLFADGYTGRARMVVDVDRGHLLGVTMVGPGAAELLHSATVAVAGQVPIDRLWHAVPCFPTISELWLRLLESYRDSFYLLV*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: lpdB, lpdB and M. tuberculosis,
dihydrolipoamide dehydrogenase,
Sanger Rv0794c, Tigr MT0817

324 bp forward orf at  [02:25]

-> Mtbook page 275

IS6110

Function

Classification IV. B.1.a
Category IV. Other
Class B. IS elements, Repeated sequences, and Phage
Group 1. IS elements
Subgroup a

Protein

108 aminoacids, 12 kDa

>Rv0795 MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: IS6110, IS6110 and M. tuberculosis,
Sanger Rv0795

936 bp forward orf at  [02:25]

-> Mtbook page 275

IS6110

Function

Classification IV. B.1.a
Category IV. Other
Class B. IS elements, Repeated sequences, and Phage
Group 1. IS elements
Subgroup a

Protein

312 aminoacids, 35,1 kDa

>Rv0796 LITRFIADHQGHREGPDGLRWGVESICTQLTELGVPIAPSTYYDHINREPSRRELRDGELKEHISRVHAANYGVYGARKVWLTLNREGIEVARCTVERLMTKLGLSGTTRGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGFAYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKDVIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKTELIKPGKPWRSIEDVELATARWVDWFNHRRLYQYCGDVPPVELEAAYYAQRQRPAAG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: IS6110, IS6110 and M. tuberculosis,
Sanger Rv0796, Tigr MT0818

1092 bp forward orf at  [02:25]

-> Mtbook page 275

IS1547

Function

Classification IV. B.1.c
Category IV. Other
Class B. IS elements, Repeated sequences, and Phage
Group 1. IS elements
Subgroup c

Protein

364 aminoacids, 40 kDa

>Rv0797 MVVVGTDAHKYSHTFVATDEVGRQLGEKTVKATTAGHATAIMWAREQFGLELIWGIEDCRNMSARLERDLLAAGQQVVRVPTKLMAQTRKSARSRGKSDPIDALAVARAVMRETDLPLATHDETSRELKLLTDRRDVLVAQRTSAINRLRWLVHELDPERAPAARSLDAAKHQQALRTWLDTQPGLVAELARAELTDIIRLTGEINTLAQRISARVHQVAPALLEIPGCAELTAAKIVGEAAGVTRFKSEAAFACHAAVAPIPVWSGNTAGQMRLSRSGNRQLNAALHRIALTQIRMTDSRGQAYYQRLQDAGKTKRAALRCLKRRLARTVFQALRTVHQPSSEHTQPAAACHRSYCSRSCLSG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: IS1547, IS1547 and M. tuberculosis,
Sanger Rv0797, Tigr MT0818

795 bp reverse orf at  [02:25]

-> Mtbook page 276

similar to bacteriocins

Function

Classification IV. E
Category IV. Other
Class E. Bacteriocin-like proteins 3

Protein

265 aminoacids, 28,8 kDa

>Rv0798c MNNLYRDLAPVTEAAWAEIELEAARTFKRHIAGRRVVDVSDPGGPVTAAVSTGRLIDVKAPTNGVIAHLRASKPLVRLRVPFTLSRNEIDDVERGSKDSDWEPVKEAAKKLAFVEDRTIFEGYSAASIEGIRSASSNPALTLPEDPREIPDVISQALSELRLAGVDGPYSVLLSADVYTKVSETSDHGYPIREHLNRLVDGDIIWAPAIDGAFVLTTRGGDFDLQLGTDVAIGYASHDTDTVRLYLQETLTFLCYTAEASVALSH*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

similar to bacteriocins,
Sanger Rv0798c, Tigr MT0819

1005 bp reverse orf at  [02:25]

-> Mtbook page 276

Function

unknown

Protein

335 aminoacids, 36 kDa

>Rv0799c VAVPAVSPQPILAPLTPAAIFLVATIGADGEATVHDALSKISGLVRAIGFRDPTKHLSVVVSIGSDAWDRLFAGPRPTELHPFVELTGPRHTAPATPGDLLFHIRAETMDVCFELAGRILKSMGDAVTVVDEVHGFRFFDNRDLLGFVDGTENPSGPIAIKATTIGDEDRNFAGSCYVHVQKYVHDMASWESLSVTEQERVIGRTKLDDIELDDNAKPANSHVALNVITDDDGTERKIVRHNMPFGEVGKGEYGTYFIGYSRTPTVTEQMLRNMFLGDPAGNTDRVLDFSTAVTGGLFFSPTIDFLDHPPPLPQAATPTLAAGSLSIGSLKGSPR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0799c, Tigr MT0820

1299 bp forward orf at  [02:25]

-> Mtbook page 276

pepC

aminopeptidase I

Function

Classification II. B.3
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 3. Proteins, peptides and glycopeptides

Protein

433 aminoacids, 46 kDa

>Rv0800 MAATAHGLCEFIDASPSPFHVCATVAGRLLGAGYRELREADRWPDKPGRYFTVRAGSLVAWNAEQSGHTQVPFRIVGAHTDSPNLRVKQHPDRLVAGWHVVALQPYGGVWLHSWLDRDLGISGRLSVRDGTGVSHRLVLIDDPILRVPQLAIHLAEDRKSLTLDPQRHINAVWGVGERVESFVGYVAQRAGVAAADVLAADLMTHDLTPSALIGASVNGTASLLSAPRLDNQASCYAGMEALLAVDVDSASSGFVPVLAIFDHEEVGSASGHGAQSDLLSSVLERIVLAAGGTREDFLRRLTTSMLASADMAHATHPNYPDRHEPSHPIEVNAGPVLKVHPNLRYATDGRTAAAFALACQRAGVPMQRYEHRADLPCGSTIGPLAAARTGIPTVDVGAAQLAMHSARELMGAHDVAAYSAALQAFLSAELSEA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pepC, pepC and M. tuberculosis,
aminopeptidase I,
Sanger Rv0800, Tigr MT0821

345 bp forward orf at  [02:26]

-> Mtbook page 277

Function

unknown

Protein

115 aminoacids, 12,5 kDa

>Rv0801 MALKVEMVTFDCSDPAKLAGWWAEQFDGTTRELLPGEFVVVARTDGPRLGFQKVPDPAPGKNRVHLDFTTKDLDAEVLRLVAAGASEVGRHQVGESFRWVVLADPEGNAFCVAGQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0801

654 bp reverse orf at  [02:26]

-> Mtbook page 277

acetyltransferase

Function

Classification IV. D
Category IV. Other
Class D. Antibiotic production and resistance

Protein

218 aminoacids, 25 kDa

>Rv0802c MSRHWPLFDLRITTPRLQLQLPTEELCDQLIDTILEGVHDPDRMPFSVPWTRASREDLPFNTLSHLWQQLAGFKRDDWSLPLAVLVDGRAVGVQALSSKDFPITRQVDSGSWLGLRYQGHGYGTEMRAAVLYFAFAELEAQVATSRSFVDNPASIAVSRRNGYRDNGLDRVAREGAMAEALLFRLTRDDWQRHRTVEVRVDGFDRCRPLFGPLEPPRY*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

acetyltransferase,
Sanger Rv0802c, Tigr MT0822

2262 bp forward orf at  [02:26]

-> Mtbook page 277

purL

phosphoribosylformylglycin-amidine synthase II

Function

Classification I. F.1
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 1. Purine ribonucleotide biosynthesis

Protein

754 aminoacids, 79,5 kDa

>Rv0803 VLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFDAEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDGGMTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKWEVLATVIGEVTDGDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADRSAKLSRPVTGDELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGMLRIDESTGRGIAVSTDASGRYTLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCADLGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGETLMLLGDTRDEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIVESALAGETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMCEARGLPAVRIGVVDQGSDAVEVQGLFAVSLAELRATSEAVLPRYFG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: purL, purL and M. tuberculosis,
phosphoribosylformylglycin-amidine synthase II,
Sanger Rv0803, Tigr MT0823

627 bp forward orf at  [02:26]

-> Mtbook page 278

Function

unknown

Protein

209 aminoacids, 21,6 kDa

>Rv0804 MSRLRALSLAAGLVGWSLVSPRLPAPWRIPLQAGLGSVLVLVTRATMGLWPPRLWAGLRLGWAAGAAAATAIAATTPVPMVRLSMSARELPASVPVWLVWHIPGGTVWAEEAAFRGALATIGARAFGRSGGRILQAGAFGLSHIADARATGEPLVLTVLATGIAGWMFGWLADRSGSLAAPLLTHLAINEAGAVAAVLVQRRSGISTRL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0804, Tigr MT0824

954 bp forward orf at  [02:26]

-> Mtbook page 278

Function

unknown

Protein

318 aminoacids, 34,2 kDa

>Rv0805 VHRLRAAEHPRPDYVLLHISDTHLIGGDRRLYGAVDADDRLGELLEQLNQSGLRPDAIVFTGDLADKGEPAAYRKLRGLVEPFAAQLGAELVWVMGNHDDRAELRKFLLDEAPSMAPLDRVCMIDGLRIIVLDTSVPGHHHGEIRASQLGWLAEELATPAPDGTILALHHPPIPSVLDMAVTVELRDQAALGRVLRGTDVRAILAGHLHYSTNATFVGIPVSVASATCYTQDLTVAAGGTRGRDGAQGCNLVHVYPDTVVHSVIPLGGGETVGTFVSPGQARRKIAESGIFIEPSRRDSLFKHPPMVLTSSAPRSPVD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0805, Tigr MT0825

1596 bp reverse orf at  [02:26]

-> Mtbook page 278

cpsY

probable UDP-glucose-4- epimerase

Function

Classification II. C.2
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 2. Surface polysaccharides, lipopolysaccharides, proteins and antigens

Protein

532 aminoacids, 60,3 kDa

>Rv0806c MPKISSRDGGRPAQRTVNPIIVTRRGKIARLESGLTPQEAQIEDLVFLRKVLNRADIPYLLIRNHKNRPVLAINIELRAGLERALAAACATEPMYAKTIDEPGLSPVLVATDGLSQLVDPRVVRLYRRRIAPGGFRYGPAFGVELQFWVYEETVIRCPVENSLSRKVLPRNEITPTNVKLYGYKWPTLDGMFAPHASDVVFDIDMVFSWVDGSDPEFRARRMAQMSQYVVGEGDDAEARIRQIDELKYALRSVNMFAPWIRRIFIATDSTPPPWLAEHPKITIVRAEDHFSDRSALPTYNSHAVESQLHHIPGLSEHFLYSNDDMFFGRPLKASMFFSPGGVTRFIEAKTRIGLGANNPARSGFENAARVNRQLLFDRFGQVITRHLEHTAVPLRKSVLIEMEREFPEEFARTAASPFRSDTDISVTNSFYHYYALMTGRAVPQEKAKVLYVDTTSYAGLRLLPKLRKHRGYDFFCLNDGSFPEVPAAQRAERVVSFLERYFPIPAPWEKIAADVSRRDFAVPRTSAPSEGA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: cpsY, cpsY and M. tuberculosis,
probable UDP-glucose-4- epimerase,
Sanger Rv0806c, Tigr MT0826

387 bp forward orf at  [02:27]

-> Mtbook page 279

Function

unknown

Protein

129 aminoacids, 13,5 kDa

>Rv0807 MSARDRVDPAKTRQVVLALADWLRDETLPAPDTDVLAAAVRLTARTLAALAPGASVEVRIPPFAAVQCISGPRHTRGTPPNVVQTDPRTWLLVATGLSGVAQARGSGALQLSGSRAGEIEAWLPLVDLG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0807, Tigr MT0828

1581 bp forward orf at  [02:27]

-> Mtbook page 279

purF

amidophosphoribosyltransferase

Function

Classification I. F.1
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 1. Purine ribonucleotide biosynthesis

Protein

527 aminoacids, 56,1 kDa

>Rv0808 VAVDSDYVTDRAAGSRQTVTGQQPEQDLNSPREECGVFGVWAPGEDVAKLTYYGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDEQTLAAMQGHVAIGHCRYSTTGDTTWENAQPVFRNTAAGTGVALGHNGNLVNAAALAARARDAGLIATRCPAPATTDSDILGALLAHGAADSTLEQAALDLLPTVRGAFCLTFMDENTLYACRDPYGVRPLSLGRLDRGWVVASETAALDIVGASFVRDIEPGELLAIDADGVRSTRFANPTPKGCVFEYVYLARPDSTIAGRSVHAARVEIGRRLARECPVEADLVIGVPESGTPAAVGYAQESGVPYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSIVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANAVENEDEMLEAVRHAIGADTLGYISLRGMVAASEQPTSRLCTACFDGKYPIELPRETALGKNVIEHMLANAARGAALGELAADDEVPVGR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: purF, purF and M. tuberculosis,
amidophosphoribosyltransferase,
Sanger Rv0808, Tigr MT0829

1092 bp forward orf at  [02:27]

-> Mtbook page 279

purM

5'-phosphoribosyl-5-aminoimidazole synthase

Function

Classification I. F.1
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 1. Purine ribonucleotide biosynthesis

Protein

364 aminoacids, 38,4 kDa

>Rv0809 MTDLAKGPGKDPGSRGITYASAGVDIEAGDRAIDLFKPLASKATRPEVRGGLGGFAGLFTLRGDYREPVLAASSDGVGTKLAIAQAMDKHDTVGLDLVAMVVDDLVVCGAEPLFLLDYIAVGRIVPERLSAIVAGIADGCMRAGCALLGGETAEHPGLIEPDHYDISATGVGVVEADNVLGPDRVKPGDVIIAMGSSGLHSNGYSLVRKVLLEIDRMNLAGHVEEFGRTLGEELLEPTRIYAKDCLALAAETRVRTFCHVTGGGLAGNLQRVIPHGLIAEVDRGTWTPAPVFTMIAQRGRVRRTEMEKTFNMGVGMIAVVAPEDTTRALAVLTARHLDCWVLGTVCKGGKQGPRAKLVGQHPRF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: purM, purM and M. tuberculosis,
5'-phosphoribosyl-5-aminoimidazole synthase,
Sanger Rv0809, Tigr MT0830

180 bp reverse orf at  [02:27]

-> Mtbook page 280

Function

unknown

Protein

60 aminoacids, 6,9 kDa

>Rv0810c MGRGRAKAKQTKVARELKYSSPQTDFQRLQRELSGTGTDRLDGDGPSDDDSWNDEDDWRR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0810c, Tigr MT0831

1104 bp reverse orf at  [02:27]

-> Mtbook page 280

Function

unknown

Protein

368 aminoacids, 39,4 kDa

>Rv0811c VAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTLDGGDRQTWLHSISTQHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTTYLDTEPWRGEPLLAYLRKMVFWSMVTPRAADMAVLSLLGPRLAEERVLDALGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIELDVVVKRGDRADWQRRLTQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGWIGGPGAGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQRPSTGDAVLAGGRTVGRLGTVVEHVELGPVALALLKRGLPGDTALVTGPEAEVAAVIDVDSLPPADDVGAGRRAVERLRGGIR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0811c, Tigr MT0832

867 bp forward orf at  [02:27]

-> Mtbook page 280

pabC

aminodeoxychorismate lyase

Function

Classification I. G.2
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 2. Folic acid

Protein

289 aminoacids, 31,1 kDa

>Rv0812 VVVTLDGEILQPGMPLLHADDLAAVRGDGVFETLLVRDGRACLVEAHLQRLTQSARLMDLPEPDLPRWRRAVEVATQRWVASTADEGALRLIYSRGREGGSAPTAYVMVSPVPARVIGARRDGVSAITLDRGLPADGGDAMPWLIASAKTLSYAVNMAVLRHAARQGAGDVIFVSTDGYVLEGPRSTVVIATDGDQGGGNPCLLTPPPWYPILRGTTQQALFEVARAKGYDCDYRALRVADLFDSQGIWLVSSMTLAARVHTLDGRRLPRTPIAEVFAELVDAAIVSDR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pabC, pabC and M. tuberculosis,
aminodeoxychorismate lyase ,
Sanger Rv0812, Tigr MT0833