606 bp forward orf at  [01:40]

-> Mtbook page 191

Function

unknown

Protein

202 aminoacids, 22,2 kDa

>Rv0525 MPEETQVHVVRHGEVHNPTGILYGRLPGFHLSATGAAQAAAVADALADRDIVAVIASPLQRAQETAAPIAARHDLAVETDPDLIESANFFEGRRVGPGDGAWRDPRVWWQLRNPFTPSWGEPYVDIAARMTTAVDKARVRGAGHEVVCVSHQLPVWTLRLYLTGKRLWHDPRRRDCALASVTSLIYDGDRLVDVVYSQPAAL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0525, Tigr MT0547

648 bp forward orf at  [01:40]

-> Mtbook page 191

Function

unknown

Protein

216 aminoacids, 23,2 kDa

>Rv0526 MQSRATRRSGALTMRRLVIAAAVSALLLTGCSGRDAVAQGGTFEFVSPGGKTDIFYDPPASRGRPGPLSGPELADPARSVSLDDFPGQVVVVNVWGQWCGPCRAEVSQLQRVYDATRGAGVSFLGIDVRDNNRQAPQDFINDRHVTYPSIYDPAMRTLIAFGGKYPTSVIPSTLVLDRQHRVAAVFLRELLAADLQPVVERVAEEEPSGRAPVGAQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0526, Tigr MT0548

777 bp forward orf at  [01:40]

-> Mtbook page 191

ccsA

cytochrome c-type biogenesis protein

Function

Classification I. B.6
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 6. Respiration

Protein

259 aminoacids, 26,5 kDa

>Rv0527 MTGFTEIAAVGPLLVAVGVCLLAGLVSFASPCVVPLVPGYLSYLAAVVGVDEQLPAGVVKPPVAARWRVAGSAALFVAGFTTVFVLGTVAVLGMTTTLITNQLLLQRVGGVLIVVMGLVFVGFIGALQRQARFTPRQLTSVAGAPVLGAVFALGWTPCLGPTLTGVITVASATEGASVARGIVLVIAYCLGLGIPFVLLAFGSAWAVAGLGWLRRHTRAIQIFGGALLIAVGAALVTGVWNDVVSWLRDAFVSDVRLPI*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ccsA, ccsA and M. tuberculosis,
cytochrome c-type biogenesis protein,
Sanger Rv0527, Tigr MT0549

1587 bp forward orf at  [01:40]

-> Mtbook page 191

probable membrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

529 aminoacids, 57,1 kDa

>Rv0528 MWRSLTSMGTALVLLFLLALAAIPGALLPQRGLNAAKVDDYLAAHPLIGPWLDELQAFDVFSSFWFTAIYVLLFVSLVGCLAPRTIEHARSLRATPVAAPRNLARLPKHAHARLAGEPAALAATITGRLRGWRSITRQQGDSVEVSAEKGYLREFGNLVFHFALLGLLVAVAVGKLFGYEGNVIVIADGGPGFCSASPAAFDSFRAGNTVDGTSLHPICVRVNNFQAHYLPSGQATSFAADIDYQADPATADLIANSWRPYRLQVNHPLRVGGDRVYLQGHGYAPTFTVTFPDGQTRTSTVQWRPDNPQTLLSAGVVRIDPPAGSYPNPDERRKHQIAIQGLLAPTEQLDGTLLSSRFPALNAPAVAIDIYRGDTGLDSGRPQSLFTLDHRLIEQGRLVKEKRVNLRAGQQVRIDQGPAAGTVVRFDGAVPFVNLQVSHDPGQSWVLVFAITMMAGLLVSLLVRRRRVWARITPTTAGTVNVELGGLTRTDNSGWGAEFERLTGRLLAGFEARSPDMAEAAAGTGRDVD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable membrane protein,
Sanger Rv0528, Tigr MT0550

972 bp forward orf at  [01:41]

-> Mtbook page 192

ccsB

cytochrome c-type biogenesis protein

Function

Classification I. B.6
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 6. Respiration

Protein

324 aminoacids, 35 kDa

>Rv0529 LNTLHVNVGLARYSDWAFTSAVVALVVALLLLAFEFAQVRGRGLAPLAVPAGSVATDSATPGIVADQRHRPFDERVGRGGLAVAYLGIGLLLACVVLRGLATQRVPWGNMYEFINLTCLSGLIAGAVVLRRARYRPLWVFLLVPVLILLTVSGRWLYANAAPVMPALQSYWLPIHVSVVSLGSGVFLVAGVASILFLVRTSRLGEPTGEGALAGMVRRLPDAQTLDGIAYRTTIFAFPVFGFGVIFGAIWAEEAWGRYWGWDPKETVSFVAWVVYAAYLHARSTAGWRDRKAAWINVAGFVAMVFNLFFVNLVTVGLHSYAGVG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: ccsB, ccsB and M. tuberculosis,
cytochrome c-type biogenesis protein,
Sanger Rv0529, Tigr MT0551

1215 bp forward orf at  [01:41]

-> Mtbook page 192

Function

unknown

Protein

405 aminoacids, 43 kDa

>Rv0530 VLVTEHPRTGVGAPDSGNGGTDHPTVQLPPVPSVGAPPAAAGGETPTRSVAGFRTQRLDPTAYGAYYSGPDEGPASPAERPPYRLEPVPHTPYPELATTTLLRPVKPPPSEGWRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGVGKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLRDADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILERFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGARSAAATLDWLQAHGHDDQVRNSIAVVNAVRPRAGKVDVGKVVEHFSRRCRAVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFPGDPRRCKPSFT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0530, Tigr MT0552

315 bp forward orf at  [01:41]

-> Mtbook page 193

unknown, membrane protein.

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

105 aminoacids, 11,4 kDa

>Rv0531 VSEAPNDKTTRGVVDILVYATARLLLVVAVSAAIFGVARLIGLTEFPVVVATLFGLIIAMPLGIWVFSPLRRRATAALAVAGERRRAERERLRARLRGESLPEEQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

unknown, membrane protein.,
Sanger Rv0531, Tigr MT0554

1782 bp forward orf at  [01:41]

-> Mtbook page 193

PE_PGRS

Function

Classification IV. C.1.b
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup b

Protein

594 aminoacids, 50,8 kDa

>Rv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

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE_PGRS, PE_PGRS and M. tuberculosis,
Sanger Rv0532, Tigr MT0556

1005 bp reverse orf at  [01:41]

-> Mtbook page 193

fabH

b -ketoacyl-ACP synthase III

Function

Classification I. H.1
Category I. Small-molecule metabolism
Class H. Lipid biosynthesis
Group 1. Synthesis of fatty and mycolic acids

Protein

335 aminoacids, 34,9 kDa

>Rv0533c MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDEWIYTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLGAKGILGFDLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLSPTIDMYDRGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVRLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLSYAAQVVRMPKG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: fabH, fabH and M. tuberculosis,
b -ketoacyl-ACP synthase III,
Sanger Rv0533c, Tigr MT0557

876 bp reverse orf at  [01:42]

-> Mtbook page 194

menA

4-dihydroxy-2-naphthoate octaprenyltransferase

Function

Classification I. G.11
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 11. Menaquinone, PQQ, ubiquinone and other terpenoids

Protein

292 aminoacids, 30 kDa

>Rv0534c VASFAQWVSGARPRTLPNAIAPVVAGTGAAAWLHAAVWWKALLALAVAVALVIGVNYANDYSDGIRGTDDDRVGPVRLVGSRLATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVGAICIAGAWLYTGGSKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWVGLAQAVATGALSCSVLVANNLRDIPTDARADKITLAVRLGDARTRMLYQGLLAVAGVLTFVLMLATPWCVVGLVAAPLALRAAGPVRSGRGGRELIPVLRDTGLAMLVWALAVAGALAFGQLS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: menA, menA and M. tuberculosis,
4-dihydroxy-2-naphthoate octaprenyltransferase,
Sanger Rv0534c, Tigr MT0558

792 bp forward orf at  [01:42]

-> Mtbook page 194

pnp

phosphorylase from Pnp/MtaP family 2

Function

Classification I. F.4
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 4. Salvage of nucleosides and nucleotides

Protein

264 aminoacids, 28 kDa

>Rv0535 MHNNGRMLGVIGGSGFYTFFGSDTRTVNSDTPYGQPSAPITIGTIGVHDVAFLPRHGAHHQYSAHAVPYRANMWALRALGVRRVFGPCAVGSLDPELEPGAVVVPDQLVDRTSGRADTYFDFGGVHAAFADPYCPTLRAAVTGLPGVVDGGTMVVIQGPRFSTRAESQWFAAAGCNLVNMTGYPEAVLARELELCYAAIALVTDVDAGVAAGDGVKAADVFAAFGENIELLKRLVRAAIDRVADERTCTHCQHHAGVPLPFELP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pnp, pnp and M. tuberculosis,
phosphorylase from Pnp/MtaP family 2,
Sanger Rv0535, Tigr MT0559

1038 bp forward orf at  [01:42]

-> Mtbook page 194

galE2

UDP-glucose 4-epimerase

Function

Classification I. A.1
Category I. Small-molecule metabolism
Class A. Degradation
Group 1. Carbon compounds

Protein

346 aminoacids, 36,2 kDa

>Rv0536 MRVLLTGAAGFIGSRVDAALRAAGHDVVGVDALLPAAHGPNPVLPPGCQRVDVRDASALAPLLAGVDLVCHQAAMVGAGVNAADAPAYGGHNDFATTVLLAQMFAAGVRRLVLASSMVVYGQGRYDCPQHGPVDPLPRRRADLDNGVFEHRCPGCGEPVIWQLVDEDAPLRPRSLYAASKTAQEHYALAWSEASGGSVVALRYHNVYGPGMPRDTPYSGVAAIFRSAVEKGKPPKVFEDGGQMRDFVHVDDVAAANLAAVHLGEADRDGFTAVNVCSGRPISILQVATAICDARGGSMSPAITGHYRSGDVRHIVADPARAARVLGFRAAVDPGEGLREFAFAPLR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: galE2, galE2 and M. tuberculosis,
UDP-glucose 4-epimerase,
Sanger Rv0536, Tigr MT0560

1431 bp reverse orf at  [01:42]

-> Mtbook page 194

unknown, possible membrane

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

477 aminoacids, 50,2 kDa

>Rv0537c VGLSSDDTRRREVVRDLAAGALLIGALFFPWNLYFGFRIPDSSKTVFGLLLAVTSLSLASLAVTFAGRRSQLRLGLNVPYLLLVLAFVVFDAIQTIRLGGTVHVPGGVGPGGWLGITGALLSAQPALTGATTDEGSHSRWLRATQFLGYASMLGAALSTGFNLSWRVRYALEPAAGASGFGKQNLAVIDTAVVYGVVALAAVLVASRWLLRPTAAEALSTVALGGSTLIAGSIVWSLPIGREIDAFHGIAQNTSTAGVGYEGYLVWAAAAAMCAPLTLFRSPNAPPIDKTVWRAASRNGLLLIAVWCLGSVAMRLTDLVVAVLLNYPFSRYDSMALAAFDLATAVLAIWLRFNMATEALPARLISSLCGLLCTFTVSRVIVGVVLAPRFQASSGGSAHPVYGNDLAQQITSTFDVVLCGLALSILAAAIVIGRLRQLPQPPHTPALSRPAGSPRIFRSAGSTHPVRPKIYRPPDHSS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

unknown, possible membrane,
Sanger Rv0537c, Tigr MT0563

1644 bp forward orf at  [01:42]

-> Mtbook page 195

possible transmembrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

548 aminoacids, 55,1 kDa

>Rv0538 MDVALGVAVTDRVARLALVDSAAPGTVIDQFVLDVAEHPVEVLTETVVGTDRSLAGENHRLVATRLCWPDQAKADELQHALQDSGVHDVAVISEAQAATALVGAAHAGSAVLLVGDETATLSVVGDPDAPPTMVAVAPVAGADATSTVDTLMARLGDQALAPGDVFLVGRSAEHTTVLADQLRAASTMRVQTPDDPTFALARGAAMAAGAATMAHPALVADATTSLPRAEAGQSGSEGEQLAYSQASDYELLPVDEYEEHDEYGAAADRSAPLSRRSLLIGNAVVAFAVIGFASLAVAVAVTIRPTAASKPVEGHQNAQPGKFMPLLPTQQQAPVPPPPPDDPTAGFQGGTIPAVQNVVPRPGTSPGVGGTPASPAPEAPAVPGVVPAPVPIPVPIIIPPFPGWQPGMPTIPTAPPTTPVTTSATTPPTTPPTTPVTTPPTTPPTTPVTTPPTTPPTTPVTTPPTTVAPTTVAPTTVAPTTVAPTTVAPATATPTTVAPQPTQQPTQQPTQQMPTQQQTVAPQTVAPAPQPPSGGRNGSGGGDLFGGF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible transmembrane protein,
Sanger Rv0538, Tigr MT0564

630 bp forward orf at  [01:43]

-> Mtbook page 195

probable glycosyltransferase

Function

Classification IV. H
Category IV. Other
Class H. Miscellaneous transferases (61)

Protein

210 aminoacids, 22,4 kDa

>Rv0539 VLPCLNEEESLPAVLAAIPAGYRALVVDNNSTDDTATVAARHGAQVVVEPRPGYGSAVHAGVLAATTPIVAVIDADGSMDAGDLPKLVAELDKGADLVTGRRRPVAGLHWPWVARVGTVVMSWRLRTRHRLPVHDIAPMRVARREALLDLGVVDRRSGYPLELLVRAAAAGWRVVELDVSYGPRTGGKSKVSGSLRGSIIAILDFWKVIS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable glycosyltransferase,
Sanger Rv0539, Tigr MT0565

660 bp forward orf at  [01:43]

-> Mtbook page 196

Function

unknown

Protein

220 aminoacids, 22,9 kDa

>Rv0540 VSCLPVSVLVVAKAPEPGRVKTRLAAAIGDKVAADIAAAALLDTLDAVAAAPVTARAVALTGDLDSAADSAEIRRRLKSFTVFRQRGDAFADRLANAHVDAADGYPVLQIGMDTPQVTAELLADCARLLLQIPAVLGLAFDGGWWVLGIRTPTAAECLRAVPMSQPDTGELTLKALRDNGIDVTLVQRLGDFDIVDDIALVRDCCAPGSRFAQATRAAGL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0540

1347 bp reverse orf at  [01:43]

-> Mtbook page 196

unknown membrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

449 aminoacids, 47,7 kDa

>Rv0541c VRIGRREGLAVAIGFVLVGAAFVLPRLNLGIKPRSDIGLERFATRAGAAPIFGYWDAHVGWGTAPAVLTAVAVVAWGPVVAHRLPWRVLTLSTWATAAAWAFSLAMIDGWQRGFAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVRVLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHGATRFPALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVLAAADWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQGIAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHRLWLAVNAAGALLLNSIIFTNW*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

unknown membrane protein,
Sanger Rv0541c, Tigr MT0566

1086 bp reverse orf at  [01:43]

-> Mtbook page 196

menE

o-succinylbenzoic acid-CoA ligase

Function

Classification I. G.11
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 11. Menaquinone, PQQ, ubiquinone and other terpenoids

Protein

362 aminoacids, 36,6 kDa

>Rv0542c VLGGSDPALVAVPTQHESLLGALRVGEQIDDDVALVVTTSGTTGPPKGAMLTAAALTASASAAHDRLGGPGSWLLAVPPYHIAGLAVLVRSVIAGSVPVELNVSAGFDVTELPNAIKRLGSGRRYTSLVAAQLAKALTDPAATAALAELDAVLIGGGPAPRPILDAAAAAGITVVRTYGMSETSGGCVYDGVPLDGVRLRVLAGGRIAIGGATLAKGYRNPVSPDPFAEPGWFHTDDLGALESGDSGVLTVLGRADEAISTGGFTVLPQPVEAALGTHPAVRDCAVFGLADDRLGQRVVAAIVVGDGCPPPTLEALRAHVARTLDVTAAPRELHVVNVLPRRGIGKVDRAALVRRFAGEADQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: menE, menE and M. tuberculosis,
o-succinylbenzoic acid-CoA ligase,
Sanger Rv0542c, Tigr MT0567

300 bp reverse orf at  [01:43]

-> Mtbook page 197

Function

unknown

Protein

100 aminoacids, 11,3 kDa

>Rv0543c VNRFLTSIVAWLRAGYPEGIPPTDSFAVLALLCRRLSHDEVKAVANELMRLGDFDQIDIGVVITHFTDELPSPEDVERVRARLAAQGWPLDDVRDREEHA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0543c, Tigr MT0569

276 bp reverse orf at  [01:43]

-> Mtbook page 197

membrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

92 aminoacids, 9,7 kDa

>Rv0544c VSAWFNYTATLKILIFSLLAGALLPGLFAVGVRLQAAGDGADATARRRPLLVAVSWAIFALVLAVVIIGVLYIARDFIAHHTGWAFLGATPK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

membrane protein,
Sanger Rv0544c, Tigr MT0569

1251 bp reverse orf at  [01:43]

-> Mtbook page 197

pitA

low-affinity inorganic phosphate transporter

Function

Classification III. A.4
Category III. Cell processes
Class A. Transport/binding proteins
Group 4. Anions

Protein

417 aminoacids, 42,7 kDa

>Rv0545c VNLQLFLLLIVVVTALAFDFTNGFHDTGNAMATSIASGALAPRVAVALPAVLNLIGAFLSTAVAATIAKGLIDANLVTLELVFAGLVGGIVWNLLTWLLGIPSSSSHALIGGIVGATIAAVGLRGVIWSGVVSKVIVPAVVAALLATLVGAVGTWLVYRTTRGVAEKRTERGFRRGQIGSASLVSLAHGTNDAQKTMGVIFLALMSYGAVSTTASVPPLWVIVSCAVAMAAGTYLGGWRIIRTLGKGLVEIKPPQGMAAESSSAAVILLSAHFGYALSTTQVATGSVLGSGVGKPGAEVRWGVAGRMVVAWLVTLPLAGLVGAFTYGLVHFIGGYPGAILGFALLWLTATAIWLRSRRAPIDHTNVNADWEGNLTAGLEAGAQPLADQRPPVPAPPAPTPPPNHRAPQFGVTTRNAP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pitA, pitA and M. tuberculosis,
low-affinity inorganic phosphate transporter,
Sanger Rv0545c, Tigr MT0570

384 bp reverse orf at  [01:44]

-> Mtbook page 197

Function

unknown

Protein

128 aminoacids, 14,3 kDa

>Rv0546c MEILASRMLLRPADYQRSLSFYRDQIGLAIAREYGAGTVFFAGQSLLELAGYGEPDHSRGPFPGALWLQVRDLEATQTELVSRGVSIAREPRREPWGLHEMHVTDPDGITLIFVEVPEGHPLRTDTRA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0546c, Tigr MT0571

882 bp reverse orf at  [01:44]

-> Mtbook page 197

putative oxidoreductase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

294 aminoacids, 31,8 kDa

>Rv0547c VSKRPLRWLTEQITLAGMRPPISPQLLINRPAMQPVDLTGKRILLTGASSGIGAAATKQFGLHRAVVVAVARRKDLLDAVADRITGDGGTAMSLPCDLSDMEAIDALVEDVEKRIGGIDILINNAGRSIRRPLAESLERWHDVERTMVLNYYAPLRLIRGLAPGMLERGDGHIINVATWGVLSEASPLFSVYNASKAALSAVSRIIETEWGSQGVHSTTLYYPLVATPMIAPTKAYDGLPALTAAEAAEWMVTAARTRPVRIAPRVAVAVNALDSIGPRWVNALMQRRNEQLNP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative oxidoreductase,
Sanger Rv0547c, Tigr MT0572

942 bp reverse orf at  [01:44]

-> Mtbook page 198

menB

naphthoate synthase

Function

Classification I. G.11
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 11. Menaquinone, PQQ, ubiquinone and other terpenoids

Protein

314 aminoacids, 34,7 kDa

>Rv0548c VVAPAGEQGRSSTALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: menB, menB and M. tuberculosis,
naphthoate synthase,
Sanger Rv0548c, Tigr MT0573

411 bp reverse orf at  [01:44]

-> Mtbook page 198

Function

unknown

Protein

137 aminoacids, 14,7 kDa

>Rv0549c VRASPTSPPEQVVVDASAMVDLLARTSDRCSAVRARLARTAMHAPAHFDAEVLSALGRMQRAGALTVAYVDAALEELRQVPVTRHGLSSLLAGAWSRRDTLRLTDALYVELAETAGLVLLTTDERLARAWPSAHAIG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0549c, Tigr MT0574

264 bp reverse orf at  [01:44]

-> Mtbook page 198

Function

unknown

Protein

88 aminoacids, 9,5 kDa

>Rv0550c LLSRRTKTIVVCTLVCMARLNVYVPDELAERARARGLNVSALTQAAISAELENSATDAWLEGLEPRSTGARHDDVLGAIDAARDEFEA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0550c, Tigr MT0575

1713 bp reverse orf at  [01:44]

-> Mtbook page 198

fadD8

acyl-CoA synthase

Function

Classification I. A.3
Category I. Small-molecule metabolism
Class A. Degradation
Group 3. Fatty acids

Protein

571 aminoacids, 61,1 kDa

>Rv0551c MSTAGDDAVGVPPACGGRSDAVGVPQLARESGAMRDQDCSGELLRSPTHNGHLLVGALKRHQNKPVLFLGDTRLTGGQLADRISQYIQAFEALGAGTGVAVGLLSLNRPEVLMIIGAGQARGYRRTALHPLGSLADHAYVLNDAGISSLIIDPNPMFVERALALLEQVDSLQQILTIGPVPDALKHVAVDLSAEAAKYQPQPLVAADLPPDQVIGLTYTGGTTGKPKGVIGTAQSIATMTSIQLAEWEWPANPRFLMCTPLSHAGAAFFTPTVIKGGEMIVLAKFDPAEVLRIIEEQRITATMLVPSMLYALLDHPDSHTRDLSSLETVYYGASAINPVRLAEAIRRFGPIFAQYYGQSEAPMVITYLAKGDHDEKRLTSCGRPTLFARVALLDEHGKPVKQGEVGEICVSGPLLAGGYWNLPDETSRTFKDGWLHTGDLAREDSDGFYYIVDRVKDMIVTGGFNVFPREVEDVVAEHPAVAQVCVVGAPDEKWGEAVTAVVVLRSNAARDEPAIEAMTAEIQAAVKQRKGSVQAPKRVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: fadD8, fadD8 and M. tuberculosis,
acyl-CoA synthase,
Sanger Rv0551c, Tigr MT0577

1602 bp forward orf at  [01:44]

-> Mtbook page 199

putative transcriptional regulator

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

534 aminoacids, 57,3 kDa

>Rv0552 MADADLVMTGTVLTVDDARPTAEAIAVADGRVIAVGDRSEVAGLVGANTRVIDLGAGCVMPGFVEAHGHPLLEAVVLSDRFVDIRPVTMRDADDVVAAIRGEVARRGPAGAYLVGWDPLLQSGLGEPTLTWLDSLAPNGPLVIIHNSGHKAYFNSHAAWLNGLTRDTADPKGAKYGRDGNGELDGTAEEIGAILPLLAGVADPSNFGAMLRAECARLNRAGLTTCSEMAFDPGYRPMVEAVRAELTVRLCTYEISNARMCTDATPGQGDDMLRQVGIKIWVDGSPWVGNIDLTFPYLDTPATRAIGVPPGSRGCANYTREQLAEIVGAYFPRGWQIACHVHGDGGVDTILDVYEEALRRNPRDDHRLRLEHVGAIRPDQLRRAAELGVTCSIFVDQIHYWGDVIVDDLFGAQRGSRWMPAGSAVAAGMRISLHNDPPVTPEEPLRNISVAATRVAPSGRVLAPEERLTVEQAIRAQTIDAAWQLFAEDAIGSLQVGKYADMVVLSADPRTVPPEQIADLAVRATFLAGRQVYRR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

putative transcriptional regulator,
Sanger Rv0552, Tigr MT0578

978 bp forward orf at  [01:45]

-> Mtbook page 199

menC

o-succinylbenzoate-CoA synthase

Function

Classification I. G.11
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 11. Menaquinone, PQQ, ubiquinone and other terpenoids

Protein

326 aminoacids, 33,9 kDa

>Rv0553 VIPVLPPLEALLDRLYVVALPMRVRFRGITTREVALIEGPAGWGEFGAFVEYQSAQACAWLASAIETAYCAPPPVRRDRVPINATVPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERVNAVRELVPMVRVDANGGWGVAEAVAAAAALTADGPLEYLEQPCATVAELAELRRRVDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGISALLDIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLFEEDVAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSLLVPSFG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: menC, menC and M. tuberculosis,
o-succinylbenzoate-CoA synthase,
Sanger Rv0553, Tigr MT0579

786 bp forward orf at  [01:45]

-> Mtbook page 200

bpoC

probable non-heme bromoperoxidase

Function

Classification III. F
Category III. Cell processes
Class F. Detoxification

Protein

262 aminoacids, 28,4 kDa

>Rv0554 VINLAYDDNGTGDPVVFIAGRGGAGRTWHPHQVPAFLAAGYRCITFDNRGIGATENAEGFTTQTMVADTAALIETLDIAPARVVGVSMGAFIAQELMVVAPELVSSAVLMATRGRLDRARQFFNKAEAELYDSGVQLPPTYDARARLLENFSRKTLNDDVAVGDWIAMFSMWPIKSTPGLRCQLDCAPQTNRLPAYRNIAAPVLVIGFADDVVTPPYLGREVADALPNGRYLQIPDAGHLGFFERPEAVNTAMLKFFASVKA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: bpoC, bpoC and M. tuberculosis,
probable non-heme bromoperoxidase,
Sanger Rv0554, Tigr MT0580

1662 bp forward orf at  [01:45]

-> Mtbook page 200

menD

2-succinyl-6-hydroxy-2,4-cyclo-hexadiene- 1-carboxylate synthase

Function

Classification I. G.11
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 11. Menaquinone, PQQ, ubiquinone and other terpenoids

Protein

554 aminoacids, 57,8 kDa

>Rv0555 VNPSTTQARVVVDELIRGGVRDVVLCPGSRNAPLAFALQDADRSGRIRLHVRIDERTAGYLAIGLAIGAGAPVCVAMTSGTAVANLGPAVVEANYARVPLIVLSANRPYELLGTGANQTMEQLGYFGTQVRASISLGLAEDAPERTSALNATWRSATCRVLAAATGARTANAGPVHFDIPLREPLVPDPEPLGAVTPPGRPAGKPWTYTPPVTFDQPLDIDLSVDTVVISGHGAGVHPNLAALPTVAEPTAPRSGDNPLHPLALPLLRPQQVIMLGRPTLHRPVSVLLADAEVPVFALTTGPRWPDVSGNSQATGTRAVTTGAPRPAWLDRCAAMNRHAIAAVREQLAAHPLTTGLHVAAAVSHALRPGDQLVLGASNPVRDVALAGLDTRGIRVRSNRGVAGIDGTVSTAIGAALAYEGAHERTGSPDSPPRTIALIGDLTFVHDSSGLLIGPTEPIPRSLTIVVSNDNGGGIFELLEQGDPRFSDVSSRIFGTPHDVDVGALCRAYHVESRQIEVDELGPTLDQPGAGMRVLEVKADRSSLRQLHAAIKAAL*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: menD, menD and M. tuberculosis,
2-succinyl-6-hydroxy-2,4-cyclo-hexadiene- 1-carboxylate synthase,
Sanger Rv0555, Tigr MT0581

513 bp forward orf at  [01:45]

-> Mtbook page 200

possible membrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

171 aminoacids, 18,7 kDa

>Rv0556 VISPKPLLHILIHGLSDELPDTRGRIVLRWLRIAVLIVTGLVTLQSVLLVAGAWRNDIAIQRNMGVAQAEVLSAGPRRSTIEFVTPDRITYRPQLGVLYPSELSTGMRIYVEYNKRDPNLVRVQHRNAGLAIIPAGSIAVVAWLIAAAALVVLAVLDKRLERRENSASATG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

possible membrane protein,
Sanger Rv0556, Tigr MT0582