1200 bp reverse orf at  [00:58]

-> Mtbook page 111

Function

unknown

Protein

400 aminoacids, 44 kDa

>Rv0293c MSGTFTADAIGPPVPIPDVPGADAGAEGLPSRSVLSARQRILVESSAIADVALRTAVASVLSATVTPAVVANALRHVNEGSERSNLNFYAELAAAHDPAKSFPAPTELPKVTSRPASPLTEWVARGTVDNIAFASGFRAINPTMRQRWSALTANNIVHAQHWRHRDGPRPTLCVIHGFMGSSYLLNGLFFSLPWYYRSGYDVLLYTLPFHGQRAEKFSPFSGFGYFTSGLSGFAEAMAQAVYDFRSIVDYLRHIGVDRIALTGISLGGYTSALLASVESRLEAVIPNCPVVMPAKLFDEWFPANKLVKLGLRLTNISRDELIAGLAYHGPLNYRPLLPKDRRMIITGLGDRMAPPEHAVTLWKQWDRCALHWFPGSHLLHVSQLDYLRRMTVFLQGLMFD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0293c, Tigr MT0306

783 bp forward orf at  [00:58]

-> Mtbook page 111

Function

unknown

Protein

261 aminoacids, 29,3 kDa

>Rv0294 MWDPDVYLAFSGHRNRPFYELVSRVGLERARRVVDLGCGPGHLTRYLARRWPGAVIEALDSSPEMVAAAAERGIDATTGDLRDWKPKPDTDVVVSNAALHWVPEHSDLLVRWVDELAPGSWIAVQIPGNFETPSHAAVRALARREPYAKLMRDIPFRVGAVVQSPAYYAELLMDTGCKVDVWETTYLHQLTGEHPVLDWITGSALVPVRERLSDESWQQFRQELIPLLNDAYPPRADGSTIFPFRRLFMVAEVGGARRSGG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0294, Tigr MT0307

801 bp reverse orf at  [00:58]

-> Mtbook page 111

Function

unknown

Protein

267 aminoacids, 29,8 kDa

>Rv0295c MSRAVRPYLVLATQRSGSTLLVESLRATGCAGEPQEFFQYLPSTGMAPQPREWFAGVDDDTILQLLDPLDPGTPDTATPVAWREHVRTSGRTPNGVWGGKLMWNQTALLQQRAAQLPDRSGDGLRAAIRDVIGNEPVFVHVHRPDVVSQAVSFWRAVQTQVWRGHPDPKRDSQAVYHAGAIAHIIRNLRDQENGWRAWFAEEGIDPIDIAYPVLWRNLTAIVASVLDAIGQDPKLAPAPMLERQANQRSDEWVDRYRAEAPRLGLPT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0295c, Tigr MT0308

1395 bp reverse orf at  [00:58]

-> Mtbook page 112

atsG

proable arylsulfatase

Function

Classification I. C.5
Category I. Small-molecule metabolism
Class C. Central intermediary metabolism
Group 5. Sulphur metabolism

Protein

465 aminoacids, 51,8 kDa

>Rv0296c VTSERATGQRENLLIVHWHDLGRYLGVYHHPDVYSPRLDRLAAEGILFTRAHATAPLCTPSRGSLFTGRYPQSNGLVGLAHHGWEYRTGVQTLPQLLSESGWYSALFGMQHETSYPKRLGFDEFDVSNSYCEYVVAKAQDWLHNRVPALDGQRFLLTAGFFETHRPYPHERYRPADSAAVELPDYLPDTPEVRQDVAEFYGSIATADEAVGRLLDTLADTGLDASTWVVFVTDHGPAFPRAKSTLYDAGTGIALIIRPPTRRAMAPRVYDELFSGVDLVPTLLDLLRLEVPADVEGVSHAPALLAPDTENAAVRDHVYTAKTYHDSFDPIRAIRTKEYSYIENYAPRPLLDLPWDIQESPAGMAVAPLVKAPRPQRELYDLRADPTETNNLLAGDDSTQGVAAIAADLAVRLHDWRQRTADVIPSDFAGSRIAERYTETYLRIHRKTPTGRSAIAADRGIDEHCS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: atsG, atsG and M. tuberculosis,
proable arylsulfatase,
Sanger Rv0296c, Tigr MT0310

1773 bp forward orf at  [00:58]

-> Mtbook page 112

PE_PGRS

Function

Classification IV. C.1.b
Category IV. Other
Class C. PE and PPE families
Group 1. PE family
Subgroup b

Protein

591 aminoacids, 49 kDa

>Rv0297 VSFVIAQPEMIAAAAGELASIRSAINAANAAAAAQTTGVMSAAADEVSTAVAALFSSHAQAYQAASAQAAAFHAQVVRTLTVDAGAYASAEAANAGPNMLAAVNAPAQALLGRPLIGNGANGAPGTGQAGGDGGLLFGNGGNGGSGAPGQAGGAGGAAGFFGNGGNGGDGGAGANGGAGGTAGWFFGFGGNGGAGGIGVAGINGGLGGAGGDGGNAGFFGNGGNGGMGGAGAAGVNAVNPGLATPVTPAANGGNGLNLVGVPGTAGGGADGANGSAIGQAGGAGGDGGNASTSGGIGIAQTGGAGGAGGAGGDGAPGGNGGNGGSVEHTGATGSSASGGNGATGGNGGVGAPGGAGGNGGHVSGGSVNTAGAGGKGGNGGTGGAGGPGGHGGSVLSGPVGDSGNGGAGGDGGAGVSATDIAGTGGRGGNGGHGGLWIGNGGDGGAGGVGGVGGAGAAGAIGGHGGDGGSVNTPIGGSEAGDGGKGGLGGDGGGRGIFGQFGAGGAGGAGGVGGAGGAGGTGGGGGNGGAIFNAGTPGAAGTGGDGGVGGTGAAGGKGGAGGSGGVNGATGADGAKGLDGATGGKGNNGNPG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PE_PGRS, PE_PGRS and M. tuberculosis,
Sanger Rv0297, Tigr MT0311

225 bp forward orf at  [00:59]

-> Mtbook page 113

Function

unknown

Protein

75 aminoacids, 8,1 kDa

>Rv0298 MTKEKISVTVDAAVLAAIDADARAAGLNRSEMIEQALRNEHLRVALRDYTAKTVPALDIDAYAQRVYQANRAAGS*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0298, Tigr MT0312

300 bp forward orf at  [00:59]

-> Mtbook page 113

Function

unknown

Protein

100 aminoacids, 10,4 kDa

>Rv0299 LIAPGDIAPRRDSEHELYVAVLSNALHRAADTGRVITCPFIPGRVPEDLLAMVVAVEQPNGTLLPELVQWLHVAALGAPLGNAGVAALREAASVVTALLC*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0299, Tigr MT0313

219 bp forward orf at  [00:59]

-> Mtbook page 113

Function

unknown

Protein

73 aminoacids, 8,1 kDa

>Rv0300 MSDVLIRDIPDDVLASLDAIAARLGLSRTEYIRRRLAQDAQTARVTVTAADLRRLRGAVAGLGDPELMRQAWR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0300, Tigr MT0314

423 bp forward orf at  [00:59]

-> Mtbook page 113

Function

unknown

Protein

141 aminoacids, 15,7 kDa

>Rv0301 VTDQRWLIDKSALVRLTDSPDMEIWSNRIERGLVHITGVTRLEVGFSAECGEIARREFREPPLSAMPVEYLTPRIEDRALEVQTLLADRGHHRGPSIPDLLIAATAELSGLTVLHVDKDFDAIAALTGQKTERLTHRPPSA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0301

630 bp forward orf at  [00:59]

-> Mtbook page 113

transcriptional regulator (TetR/AcrR family)

Function

Classification I. J.1
Category I. Small-molecule metabolism
Class J. Broad regulatory functions
Group 1. Repressors/activators

Protein

210 aminoacids, 23,4 kDa

>Rv0302 VGVPAKKKQQQGERSRESILDATERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFAAIPTWDEAHGPVEQRSERQLTELVSLQSQHPDFLRLFYLLSMERSQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

transcriptional regulator (TetR/AcrR family),
Sanger Rv0302, Tigr MT0315

906 bp forward orf at  [00:59]

-> Mtbook page 113

similar to NADPH dehydrogenase

Function

Classification I. B.7
Category I. Small-molecule metabolism
Class B. Energy metabolism
Group 7. Miscellaneous oxidoreductases and oxygenases 171

Protein

302 aminoacids, 32,7 kDa

>Rv0303 MNTGTAVITGASSGLGLQCARALLRRDASWHVVLAVRDPARGRAAMEELGEPNRCSVLEVDLASVRSVRSFVETVRTTPLPPIRALVCNAGLQVVSGIAFTDDGVEMTFGVNHLGHFALVTGILDWLARPARIVVVSSGTHDPSKHTGMPDPRYTCAADLAHPPTDQNTPAEGRRRYTTSKLCNVLFTYELDRRLDHGEQGVMVNAFDPGLMPGSGLARDYPPILRLAYRLLSPMLRVLPFVHSTRVSGEHLAALAVDPRFAGVTGQYFAGAKAIRSSAESYDRAKALDLWETSERLLAQVT*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

similar to NADPH dehydrogenase,
Sanger Rv0303, Tigr MT0316

6612 bp reverse orf at  [00:59]

-> Mtbook page 114

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

2204 aminoacids, 215,7 kDa

>Rv0304c MNLVSTTSGMSGFLNVGALGSGVANVGNTISGIYNVGTSDLSTPAVNSGLANIGTNIAGLLRDGAGTAAINLGLANHGNLNVGFASLGGFNFGGATIGHNNVGIGNTGIFDVGLANLGSYNIGFGNLGDDNLGFGNFGSYNIGFGNVGNDNLGFANAGGGNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSGNIGLFNSGSNNIGFFNSGSGNFGIANSGSFNTGIGNTGNTNTGLFNSGDVNTGAFNPGSFNTGSFNTGSFNTGGFNPGNTNTGYLNIGNYNTGIANTGDVDTGAFITGNYSNGLFLSGDYQGLVGLNLVIDMPLPISLGVNIPIDIPITASAGNITLMGVTIPPTGDIVLSSIAGQRAHFGPITIPNITVVGPTTTVAIGGPNTAITITGGGAIRIPLISIPAAPGFGNSTTNPSSGFFNTGAGGASGFGNFGGANSGFWNLASATSGASGLLNVGALGSGLANVGTTVSGFYNTSTSDLATPAFNSGLANISTSIAGLLRDSTGTMVLNLGLANHGTLNVGIANLGDYNIGFANLGSANFGSANIGGNNIGGANTGIFDIGLANLGSYNIGFGNFGDDNLGFGNLGSYNVGFGNLGNDNLGFANTGSNNIGFANTGSNNIGIGLTGDGQIGFGSLNSGSGNIGLFNSGSGNIGFFNSGNGNVGIGNTGTANFGLGNTGSTNTGFFNSGDVNTGIGNTGSFNTGSFNPGDSNTGDFNPGSYNTGLGNTGDVDTGAFISGSYSNGFLWSGNYQGLIGLHAALAIPEIALTFGVDIPIHIPINIDAGVVTLQGFSIVAAENNIDFTPIIIPTINITLPTAAITVGGPTTSIGITASAGIGSITIPIIDIPATSGFGNSTTSPSSGFFNSGAGSASGFLNVVAGASGISGYLNVGALGSGVTNVGHTVSGFYNASALDLVTPAFASGLMRDGMGTMTLNLGLANLGSNNAGFGNTGIFDVGVANLGNYNIGFGNFGDDNLGFANLGSYNIGVANTGSNNIGFANTGSNNIGIGLTGTGQIGIGALNSGSGNIGLFNSGDGNIGFFNSGTGNFGIGNTGTGNFGIGNSGSTSTGLFNSGDGNTGGFNPGNFNTGNFNTGSFNTGGFNAGNTNTGHFNTGNYNTGIANTGDVSTGAFISGNYSNGILWRGDYQGLIGYSYALTIPEIPAHLDVNIPIDIPITGSFTDLVVDNFTIPIIGFESFAFSFHIHTEPDIGPIIVPSFVLSVPTFAIAVGGPTTAINISATAGLGPITIPIIDIPAAPGIGNSTTSPSSGFFNTGAGTASGFGNVGGNTSGLWNLASAASGVSGLLNVGALGSGVANVGNTISGIYNTSPLDLGTPAFGSGLANIAGLLQGGAGTTILDLAGLGNLNVGLANLGGSNFGIGNTGIFNVGFANVGNHNIGLANLGNYSVGFANSGNYHIGIANTGSANIGFANTGSGNIGIGLTGTGQIGFGSFNSGSHNIGLFNSGDGNVGFFNSGTGNVGIGNTGTANFGIANSGSFNTGLGNTGSTNTGLFNPGNVNTGVGNTGSINTGSINTGSFNTGSTNTGSFNLGDHNTGSFNSGDYNTGYFNAGDYNTGVANTGNVNTGAFISGNYSNGFFWRGDYQGLIGLSTTITIPEIPYRYDLSVPIDIPITGTVVATTPNSFTIPGFQIRVLLGPAAVLVNEMIGPITIDVNQVIAIDSPIQQTISMVGTGGFGPIPIGISIGGTPGFGNSTTGPSSGFFHTGAGHVSGFGNFGAGNMSGSGNFGAGNSGFFNAGGLGNSGLLNFGALQSGLANLGNTISGVYNTSTLDLATPAFGSGIANIGANLAGLFLDNTGNLTLNFGVANQGGLNAGIGNLGSVNIGFVNTGDSNLGIGNLGDLNFGGVNIGGNNIGIANTGIFDIGLANLGSYNIGLANLGDDNLGFGNAGSYNIGFANFGSDNLGFANTGSYNIGFANTGNNNIGVGLTGNGQIGIGSLNSGSNNIGLFNSGSGNIGFFNSGTGNVGIFNTGTGNFGLANSGGFNTGIGNAGSTNTGVFNPGDLNTGSFNPGSFNTGGFNPGSGNTGYLNTGDYNTGVANTGDVDTGAFITGSYSNGFLVSGDYQGLIGLPLLGIPVTPGYFNLTGGPSSGFFNSGAGSVSGFVNSGAGLSGYLNTGALGSGVANVGNTISGWLNASALDLATPGFLSGIGNFGTNLAGFFRG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv0304c, Tigr MT0317

2889 bp reverse orf at  [01:00]

-> Mtbook page 116

PPE

Function

Classification IV. C.2
Category IV. Other
Class C. PE and PPE families
Group 2.PPE family (68)

Protein

963 aminoacids, 99 kDa

>Rv0305c MDFVVSAPEVNSLRMYLGAGSGPMLAAAAAWDGLADELAVAASWFGSVTSGLADAAWRGPAAVAMARAVAPYLGWLISATAQAEQAAAQARVAVATFEAARAATVHPAIVAANRAVLVSLVSSNLLGFNAPAIAATEAAYERMWAQDVAAMVGYHAGASAAVSALMPFTQQLKKLAGLSERLTSAAAAAAGPPSAAGFNLGLANVGANNVGNGNVGVFNVGFGNLGSYNLGFANLGSDNLGLANLGGHNIGFANTGSNNVGFGNTGSNNVGIGLTGNGQIGFGSFNSGSHNIGLFNSGSGNVGLFNSGTGNFGIGNSGTGNFGLGNTGSTNTGWFNTGDVNTGGFNPGSYNTGNFNTGNYNTGSFNAGNYNTGYFNTGDYNTGVANTGNVNTGAFIAGNYSNGVLWRGDYQGLIGADIALEIPAIPINAQLFSMPIHQVMVMPGSVMTIPGMRLPFTSIVPFVVYYGPVELPQSTLTLPTVTITVGGPTTTIDGNLTGMVGGVSIPLIKIPAAPGFGNSTTSPSSGFFNAGAGTASGFGNFGGGASGFWNLASATSGLSGFGNVGALGSGVANVGNTISGLYNTSTSNLATPAFNSGLLHHSVGTMTLNFGLANVGGNNVGGANAGIFNVGLANLGDYNIGFGNLGGDNLGFAHAGSYNIGFANTGSNNLGFANTGDNNIGFANIGSNNIGIGLTGSGQIGFGSLNSGSHNIGLFNSGDGNIGLFNSGSGNFGIGNAGTGNWGIGNSGAGNFGIGNAGSTNTGLFNSGDLNTGSLNPGSYNTGSVNTGSVNTGGFNAGNYNTGYFNTGDLQHRHGEHRQYQHRRFHLRQPQQRPSVAGRQPGSDRPRHRRRHSRNPDCERRREYPDSHTDHRQLHGHRIQRARSSTEHSRHCYFFRTRRYRPLHRPSDTDNRSHTCGHGGWTHYRDQYRRHCGRRRHQHPDYPYSSDSRLRQLDRRTVVGLLQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: PPE, PPE and M. tuberculosis,
Sanger Rv0305c, Tigr MT0318

669 bp forward orf at  [01:01]

-> Mtbook page 117

similar to BluB cobalamin synthesis protein R. capsulatus

Function

Classification I. G.13
Category I. Small-molecule metabolism
Class G. Biosynthesis of cofactors, prosthetic groups and carriers
Group 13. Cobalamin

Protein

223 aminoacids, 24,9 kDa

>Rv0306 MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPSVGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALGAREEEFLALKVEGILDCAELLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLAARSEGLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWSYPSALATDHHHGE*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

similar to BluB cobalamin synthesis protein R. capsulatus ,
Sanger Rv0306, Tigr MT0319

480 bp reverse orf at  [01:01]

-> Mtbook page 117

Function

unknown

Protein

160 aminoacids, 17,2 kDa

>Rv0307c MAVIVRKWFGLGRLPADLRCQVEAEGLIYLAEYVAVTRRFTGVIPGLRASHSIASYVGALAFTEQRVLGTLSMVPKLAGRVVDARWDGPQAGAATAEISPTGLQLDLDVADVDPKFSGQLALHFKATIGEDVLSRLPRRSLAFDVPAEYVNLAVGVTYSP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0307c, Tigr MT0320

714 bp forward orf at  [01:01]

-> Mtbook page 117

Function

unknown

Protein

238 aminoacids, 25,6 kDa

>Rv0308 MTRPQALLAVSLAFVATAVYAVMWVGHSQDWGWLHSFDWSLLNAAHDIGIKNPAWVRFWDGVSLILGPVVLRPLGLLAAMVALAKRKIRIALLLLACLPLNAIMTIAAKSVAHRPRPATALVSAHSTSFPSGHALEATASVLALLTVLLPMLHSRFTRHIAITVGALCVLTVGVARVALNVHHPTDVVAGWALGYLYFLVCLCVFRPPSIFGAQRASHALSPPVEVSRQPEPEVDTAR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0308, Tigr MT0321

654 bp forward orf at  [01:01]

-> Mtbook page 117

Function

unknown

Protein

218 aminoacids, 22,5 kDa

>Rv0309 MSRLLALLCAAVCTGCVAVVLAPVSLAVVNPWFANSVGNATQVVSVVGTGGSTAKMDVYQRTAAGWQPLKTGITTHIGSAGMAPEAKSGYPATPMGVYSLDSAFGTAPNPGGGLPYTQVGPNHWWSGDDNSPTFNSMQVCQKSQCPFSTADSENLQIPQYKHSVVMGVNKAKVPGKGSAFFFHTTDGGPTAGCVAIDDATLVQIIRWLRPGAVIAIAK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0309, Tigr MT0322

489 bp reverse orf at  [01:01]

-> Mtbook page 117

Function

unknown

Protein

163 aminoacids, 18,2 kDa

>Rv0310c VCCNGVVTPGDPADIAAIKQLKYRYLRALDTKHWDDFTDTLAEDVTGDYGSSVGTELHFTNRADLVDYLRQALGPGVITEHRVTHPEITVTGDTATGIWYLQDRVIVAEFNFMLIGAAFYHDQYRRTTDGWRISATGYDRTYEATMSLAGLNFNIRPGRALAD*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0310c, Tigr MT0323

1227 bp forward orf at  [01:01]

-> Mtbook page 118

Function

unknown

Protein

409 aminoacids, 44,6 kDa

>Rv0311 MSQSRYAGLSRSELAVLLPELLLIGQLIDRSGMAWCIQAFGRQEMLQIAIEEWAGASPIYTKRMQKALNFEGDDVPTIFKGLQLDIGAPPQFMDFRFTLHDRWHGEFHLDHCGALLDVEPMGDDYVVGMCHTIEDPTFDATAIATNPRAQVRPIHRPPRKPADRHPHCAWTVIIDESYPEAEGIPALDAVRETKAATWELDNVDASDDGLVDYSGPLVSDLDFGAFSHSALVRMADEVCLQMHLLNLSFAIAVRKRAKADAQLAISVNTRQLIGVAGLGAERIHRAMALPGGIEGALGVLELHPLLNPAGYVLAETSPDRLVVHNSPAHADGAWISLCTPASVQPLQAIATAVDPHLKVRISGTDTDWTAELIEADAPASELPEVLVAKVSRGSVFQFEPRRSLPLTVK*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0311, Tigr MT0324

1860 bp forward orf at  [01:02]

-> Mtbook page 118

Function

unknown

Protein

620 aminoacids, 64,1 kDa

>Rv0312 MYDPLGLSIGTTNLVAAGNGGPPVTRRAVLTLYPHCAPKIGVPSQNPNLIEPGALMSGFVERIGDAVALVSPDGSVHDPDLLLVEALDAMVLTAGADASSSEIAIAVPAHWKPGAVHALRNGLRTHVGFVRSGMAPRLVSDAIAALTAVNSELGLPHGSVVGLLDFGGSATYVTLVETKSDSRTSDFQPVSATARYQDFSGSQIDQALLLRVIDQFGYGDDVDPASTAAVGQLGQLREQCRAAKERLSTDVATELFAELAGCSSSIEMTREQLEDLIQDPLTGFIYAFDDMLARHNASWADLAAVVTVGGGANIPLVTQRLSFHTRRPVLTASQPGCAAAMGALLLANRGGERDSRTRTSIGLATAAAAGTSVIELPAGDVMVIDHEALTDRELAWSQTDFPSEAPARFEGDSYNEGGPCWSMRLNAVEPPKGPAWRRIRVSQLLIGVSAVVAMTAIGGVALTLTAIERRPSPLPTPIVPGLAPMPPGSVVPSSRAPTPPPPPSTVAPLPSAAPAPTTVAPAPPPPTQVVTTTTAPPVTTTPRPSPTTTTTTAPPSTTTTTEPPVTTTSTIPTIPTTTTTVKMTTEWLHVPFLPVPIPVPIPQNPGAGEPQNPFGSLGSG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0312, Tigr MT0326

384 bp forward orf at  [01:02]

-> Mtbook page 119

Function

unknown

Protein

128 aminoacids, 13,9 kDa

>Rv0313 VGDYGPFGFDPDEFDRVIREGSEGLRDAFERIGRFLSSSGAGTGWSAIFEDLSRRSRPAPETAGEAGDGVWAIYTVDADGGARVEQVYATELDALRANKDNTDPKRKVRFLPYGIAVSVLDDPVDEAQ*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0313, Tigr MT0327

660 bp reverse orf at  [01:02]

-> Mtbook page 119

unknown hydrophobic protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

220 aminoacids, 22,5 kDa

>Rv0314c MIVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSGGYTYPPGPPPPPYSYGGPFGGPSPRSSSGNRAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVPTPTAQPATTLPPAGASLSVSGVNVNRTIACNDSIVSVSGMSNTVVITGHCTSLTVSGMRNSVTVDSVDTIEAAGFNNEVTYHSGSPKISNAGGSNSVQQG*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

unknown hydrophobic protein,
Sanger Rv0314c, Tigr MT0328

882 bp forward orf at  [01:02]

-> Mtbook page 119

probable b -1,3-glucanase

Function

Classification II. B.4
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 4. Polysaccharides, lipopolysaccharides and phospholipids

Protein

294 aminoacids, 32,2 kDa

>Rv0315 MLMPEMDRRRMMMMAGFGALAAALPAPTAWADPSRPAAPAGPTPAPAAPAAATGGLLFHDEFDGPAGSVPDPSKWQVSNHRTPIKNPVGFDRPQFFGQYRDSRQNVFLDGNSNLVLRATREGNRYFGGLVHGLWRGGIGTTWEARIKFNCLAPGMWPAWWLSNDDPGRSGEIDLIEWYGNGTWPSGTTVHANPDGTAFETCPIGVDGGWHNWRVTWNPSGMYFWLDYADGIEPYFSVPATGIEDLNEPIREWPFNDPGYKVFPVLNLAVGGSGGGDPATGSYPQEMLVDWVRVF*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable b -1,3-glucanase,
Sanger Rv0315, Tigr MT0329

612 bp forward orf at  [01:02]

-> Mtbook page 119

probable muconolactone isomerase

Function

Classification II. B.6
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 6. Aromatic hydrocarbons

Protein

204 aminoacids, 22,3 kDa

>Rv0316 MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFAADDNGELEQLLASMPPRSWRTDDVTPLGAHPNDPVGQGITIAPGKGPEFLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQRTLGLWRARDPGELMAILESLPLAGWMTIETTPLSPHPDDPIRMP*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

probable muconolactone isomerase,
Sanger Rv0316, Tigr MT0330

768 bp reverse orf at  [01:02]

-> Mtbook page 119

glpQ2

glycerophosphoryl diester phosphodiesterase

Function

Classification I. C.1
Category I. Small-molecule metabolism
Class C. Central intermediary metabolism
Group 1. General

Protein

256 aminoacids, 28,3 kDa

>Rv0317c VEFLRHGGRIAMAHRGFTSFRLPMNSMGAFQEAAKLGFRYIETDVRATRDGVAVILHDRRLAPGVGLSGAVDRLDWRDVRKAQLGAGQSIPTLEDLLTALPDMRVNIDIKAASAIEPTVNVIERCNAHNRVLIGSFSERRRRRALRLLTKRVASSAGTGALLAWLTARPLGSRAYAWRMMRDIDCVQLPSRLGGVPVITPARVRGFHAAGRQVHAWTVDEPDVMHTLLDMDVDGIITDRADLLRDVLIARGEWDGA*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: glpQ2, glpQ2 and M. tuberculosis,
glycerophosphoryl diester phosphodiesterase,
Sanger Rv0317c, Tigr MT0332

792 bp reverse orf at  [01:03]

-> Mtbook page 120

unknown transmembrane protein

Function

Classification II. C.5
Category II. Macromolecule metabolism
Class C. Cell envelope
Group 5. Other membrane proteins 211

Protein

264 aminoacids, 27,2 kDa

>Rv0318c LSLAVTMFKRARAEIFDRNREVGISNVTTAASLVTFPVLAGILGGVVPSVRTPSAAMVSGVQHFAAGIVMAAVAGEVLPDLRSRGPLWLIVVGFSAGVAVLVALRRFDGHGEHQDGDDVGELPVGFLTVVAVDLFIDGLLVATGATVSSRTAIIITIALTVEVLFLGLAVALRLAGSGMPRIRAAATTSALSLVIAVGGVSGAVALGRAGNTVLTLVLAFAAGALLWLVVEELLVEAHETPERPWMAVMFFAGFLILYGLGVME*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

unknown transmembrane protein,
Sanger Rv0318c, Tigr MT0333

666 bp forward orf at  [01:03]

-> Mtbook page 120

pcp

pyrrolidone-carboxylate peptidase

Function

Classification II. B.3
Category II. Macromolecule metabolism
Class B. Degradation of macromolecules
Group 3. Proteins, peptides and glycopeptides

Protein

222 aminoacids, 23,2 kDa

>Rv0319 MSKVLVTGFGPYGVTPVNPAQLTAEELDGRTIAGATVISRIVPNTFFESIAAAQQAIAEIEPALVIMLGEYPGRSMITVERLAQNVNDCGRYGLADCAGRVLVGEPTDPAGPVAYHATVPVRAMVLAMRKAGVPADVSDAAGTFVCNHLMYGVLHHLAQKGLPVRAGWIHLPCLPSVAALDHNLGVPSMSVQTAVAGVTAGIEAAIRQSADIREPIPSRLQI*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: pcp, pcp and M. tuberculosis,
pyrrolidone-carboxylate peptidase,
Sanger Rv0319, Tigr MT0334

660 bp forward orf at  [01:03]

-> Mtbook page 120

Function

unknown

Protein

220 aminoacids, 23,1 kDa

>Rv0320 VGRHELARDRRKSSAVLAAVLAPAAVFFATGGDVSTLAARADANPVLGDDAPCCVQIVPVAPLAFSSQISGGEIGTGLAASQFASASRWRIVSRYLPVGVAPEQGLQVKTVLTARSISAAFPEIREIGGVRPDALRWHPNGLALDVMVPNPGTAEGIALGNEIVAFVLKNATRFGMQDVIWRGAYYTPNGARTTGAGHYDHIHITTVGGGYPTGEELYIR*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

Sanger Rv0320, Tigr MT0335

570 bp forward orf at  [01:03]

-> Mtbook page 120

dcd

deoxycytidine triphosphate deaminase

Function

Classification I. F.3
Category I. Small-molecule metabolism
Class F. Purines, pyrimidines, nucleosides and nucleotides
Group 3. 2'-deoxyribonucleotide metabolism

Protein

190 aminoacids, 20,8 kDa

>Rv0321 VLLSDRDLRAEISSGRLGIDPFDDTLVQPSSIDVRLDCLFRVFNNTRYTHIDPAKQQDELTSLVQPVDGEPFVLHPGEFVLGSTLELFTLPDNLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHITLELSNVANLPITLWPGMKIGQLCMLRLTSPSEHPYGSSRAGSKYQGQRGPTPSRSYQNFIRST*

Pedant links: Pedant report, prosite patterns,
intragenome comparison,
blastp homologues

Lookup

PubMed: dcd, dcd and M. tuberculosis,
deoxycytidine triphosphate deaminase,
Sanger Rv0321, Tigr MT0336